Effects of breed, gender, exercise and white-coat effect on markers of endothelial function in dogs

Sophia Gry Moesgaard; A.V. Holte; T. Mogensen; J. Mølbak; Annemarie Thuri Kristensen; Asger Lundorff Jensen; T. Teerlink; A.J. Reynolds; Lisbeth Høier Olsen

doi:10.1016/j.rvsc.2006.09.003

Effects of breed, gender, exercise and white-coat effect on markers of endothelial function in dogs

Sophia Gry Moesgaard, A.V. Holte, T. Mogensen, J. Mølbak, Annemarie Thuri Kristensen, Asger Lundorff Jensen, T. Teerlink, A.J. Reynolds, Lisbeth Høier Olsen

28 Citations (Scopus)

Abstract

This study examines how systemic biomarkers of endothelial function and nitric oxide metabolism are affected by exercise in dogs. Furthermore, breed variation and white-coat effect have been tested by sampling three different dog breeds both in their home and in a clinical setting. Short-term exercise increased plasma nitrate and nitrite (NOx) and von Willebrand factor (vWf). There was significant difference between Pointers and the small dog breeds Cairn Terriers and Cavalier King Charles Spaniels in the general plasma levels of vWf and asymmetric dimethylarginine (ADMA9. NOx and vWf were significantly higher when the sample was taken in the laboratory cf. at home, whereas ADMA and L-arginine were significantly lower. In conclusion, both short-term exercise and white-coat effect influence several plasma markers of endothelial function depending also on the breed and gender of the dogs. These findings should be considered in future studies concerning endothelial function in dogs.

Original language	English
Journal	Research in Veterinary Science
Volume	82
Issue number	3
Pages (from-to)	409-415
Number of pages	7
ISSN	0034-5288
DOIs	https://doi.org/10.1016/j.rvsc.2006.09.003
Publication status	Published - 2007

Keywords

Former LIFE faculty
ADMA
SDMA
L-arginine
NOx
vWf

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10.1016/j.rvsc.2006.09.003

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@article{3a550280a1c211ddb6ae000ea68e967b,

title = "Effects of breed, gender, exercise and white-coat effect on markers of endothelial function in dogs",

abstract = "This study examines how systemic biomarkers of endothelial function and nitric oxide metabolism are affected by exercise in dogs. Furthermore, breed variation and white-coat effect have been tested by sampling three different dog breeds both in their home and in a clinical setting. Short-term exercise increased plasma nitrate and nitrite (NOx) and von Willebrand factor (vWf). There was significant difference between Pointers and the small dog breeds Cairn Terriers and Cavalier King Charles Spaniels in the general plasma levels of vWf and asymmetric dimethylarginine (ADMA9. NOx and vWf were significantly higher when the sample was taken in the laboratory cf. at home, whereas ADMA and L-arginine were significantly lower. In conclusion, both short-term exercise and white-coat effect influence several plasma markers of endothelial function depending also on the breed and gender of the dogs. These findings should be considered in future studies concerning endothelial function in dogs.",

keywords = "Former LIFE faculty, ADMA, SDMA, L-arginine, NOx, vWf",

author = "Moesgaard, {Sophia Gry} and A.V. Holte and T. Mogensen and J. M{\o}lbak and Kristensen, {Annemarie Thuri} and Jensen, {Asger Lundorff} and T. Teerlink and A.J. Reynolds and Olsen, {Lisbeth H{\o}ier}",

year = "2007",

doi = "10.1016/j.rvsc.2006.09.003",

language = "English",

volume = "82",

pages = "409--415",

journal = "Research in Veterinary Science",

issn = "0034-5288",

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TY - JOUR

T1 - Effects of breed, gender, exercise and white-coat effect on markers of endothelial function in dogs

AU - Moesgaard, Sophia Gry

AU - Holte, A.V.

AU - Mogensen, T.

AU - Mølbak, J.

AU - Kristensen, Annemarie Thuri

AU - Jensen, Asger Lundorff

AU - Teerlink, T.

AU - Reynolds, A.J.

AU - Olsen, Lisbeth Høier

PY - 2007

Y1 - 2007

N2 - This study examines how systemic biomarkers of endothelial function and nitric oxide metabolism are affected by exercise in dogs. Furthermore, breed variation and white-coat effect have been tested by sampling three different dog breeds both in their home and in a clinical setting. Short-term exercise increased plasma nitrate and nitrite (NOx) and von Willebrand factor (vWf). There was significant difference between Pointers and the small dog breeds Cairn Terriers and Cavalier King Charles Spaniels in the general plasma levels of vWf and asymmetric dimethylarginine (ADMA9. NOx and vWf were significantly higher when the sample was taken in the laboratory cf. at home, whereas ADMA and L-arginine were significantly lower. In conclusion, both short-term exercise and white-coat effect influence several plasma markers of endothelial function depending also on the breed and gender of the dogs. These findings should be considered in future studies concerning endothelial function in dogs.

AB - This study examines how systemic biomarkers of endothelial function and nitric oxide metabolism are affected by exercise in dogs. Furthermore, breed variation and white-coat effect have been tested by sampling three different dog breeds both in their home and in a clinical setting. Short-term exercise increased plasma nitrate and nitrite (NOx) and von Willebrand factor (vWf). There was significant difference between Pointers and the small dog breeds Cairn Terriers and Cavalier King Charles Spaniels in the general plasma levels of vWf and asymmetric dimethylarginine (ADMA9. NOx and vWf were significantly higher when the sample was taken in the laboratory cf. at home, whereas ADMA and L-arginine were significantly lower. In conclusion, both short-term exercise and white-coat effect influence several plasma markers of endothelial function depending also on the breed and gender of the dogs. These findings should be considered in future studies concerning endothelial function in dogs.

KW - Former LIFE faculty

KW - ADMA

KW - SDMA

KW - L-arginine

KW - NOx

KW - vWf

U2 - 10.1016/j.rvsc.2006.09.003

DO - 10.1016/j.rvsc.2006.09.003

M3 - Journal article

C2 - 17092526

SN - 0034-5288

VL - 82

SP - 409

EP - 415

JO - Research in Veterinary Science

JF - Research in Veterinary Science

IS - 3

ER -

Effects of breed, gender, exercise and white-coat effect on markers of endothelial function in dogs

Abstract

Keywords

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