TY - JOUR
T1 - Effects of breed, gender, exercise and white-coat effect on markers of endothelial function in dogs
AU - Moesgaard, Sophia Gry
AU - Holte, A.V.
AU - Mogensen, T.
AU - Mølbak, J.
AU - Kristensen, Annemarie Thuri
AU - Jensen, Asger Lundorff
AU - Teerlink, T.
AU - Reynolds, A.J.
AU - Olsen, Lisbeth Høier
PY - 2007
Y1 - 2007
N2 - This study examines how systemic biomarkers of endothelial function and nitric oxide metabolism are affected by exercise in dogs. Furthermore, breed variation and white-coat effect have been tested by sampling three different dog breeds both in their home and in a clinical setting. Short-term exercise increased plasma nitrate and nitrite (NOx) and von Willebrand factor (vWf). There was significant difference between Pointers and the small dog breeds Cairn Terriers and Cavalier King Charles Spaniels in the general plasma levels of vWf and asymmetric dimethylarginine (ADMA9. NOx and vWf were significantly higher when the sample was taken in the laboratory cf. at home, whereas ADMA and L-arginine were significantly lower. In conclusion, both short-term exercise and white-coat effect influence several plasma markers of endothelial function depending also on the breed and gender of the dogs. These findings should be considered in future studies concerning endothelial function in dogs.
AB - This study examines how systemic biomarkers of endothelial function and nitric oxide metabolism are affected by exercise in dogs. Furthermore, breed variation and white-coat effect have been tested by sampling three different dog breeds both in their home and in a clinical setting. Short-term exercise increased plasma nitrate and nitrite (NOx) and von Willebrand factor (vWf). There was significant difference between Pointers and the small dog breeds Cairn Terriers and Cavalier King Charles Spaniels in the general plasma levels of vWf and asymmetric dimethylarginine (ADMA9. NOx and vWf were significantly higher when the sample was taken in the laboratory cf. at home, whereas ADMA and L-arginine were significantly lower. In conclusion, both short-term exercise and white-coat effect influence several plasma markers of endothelial function depending also on the breed and gender of the dogs. These findings should be considered in future studies concerning endothelial function in dogs.
KW - Former LIFE faculty
KW - ADMA
KW - SDMA
KW - L-arginine
KW - NOx
KW - vWf
U2 - 10.1016/j.rvsc.2006.09.003
DO - 10.1016/j.rvsc.2006.09.003
M3 - Journal article
C2 - 17092526
SN - 0034-5288
VL - 82
SP - 409
EP - 415
JO - Research in Veterinary Science
JF - Research in Veterinary Science
IS - 3
ER -