Effect of vitamins E+C and taurine on the oxidative state of DNA in the liver of growing pigs

E. Sawosz; A. Strawa; Andrzej Chwalibog; T. Niemiec; I. Kosieradzka; I. Dudkowska

Effect of vitamins E+C and taurine on the oxidative state of DNA in the liver of growing pigs

E. Sawosz, A. Strawa, Andrzej Chwalibog, T. Niemiec, I. Kosieradzka, I. Dudkowska

Abstract

Growing pigs (n=21)at an initial liveweight of 30 kg were divided into three groups of 7 animals each and housed in individual cages for 100 days. The pigs were fed with similar diets (13.5 MJ ME and 178 g crude protein/kg) but with different additions of vitamins C+E and taurine. The antioxidative vitamins E and C supplied to diets with high energy concentrations (containing lard) can act as pro-oxidants on liver DNA in growing pigs. Taurine decreased the concentration of products from nucleotide oxidation, but in the presence of vitamin E and C, promoted hepatocyte lesions.

Original language	English
Journal	Journal of Animal and Feed Sciences
Volume	13
Issue number	Suppl. 2
Pages (from-to)	51-54
Number of pages	4
ISSN	1230-1388
Publication status	Published - 2004

Keywords

Former LIFE faculty
pigs, vitamin E, vitamin C, taurine, DNA oxidation

Cite this

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title = "Effect of vitamins E+C and taurine on the oxidative state of DNA in the liver of growing pigs",

abstract = "Growing pigs (n=21)at an initial liveweight of 30 kg were divided into three groups of 7 animals each and housed in individual cages for 100 days. The pigs were fed with similar diets (13.5 MJ ME and 178 g crude protein/kg) but with different additions of vitamins C+E and taurine. The antioxidative vitamins E and C supplied to diets with high energy concentrations (containing lard) can act as pro-oxidants on liver DNA in growing pigs. Taurine decreased the concentration of products from nucleotide oxidation, but in the presence of vitamin E and C, promoted hepatocyte lesions.",

keywords = "Former LIFE faculty, pigs, vitamin E, vitamin C, taurine, DNA oxidation",

author = "E. Sawosz and A. Strawa and Andrzej Chwalibog and T. Niemiec and I. Kosieradzka and I. Dudkowska",

year = "2004",

language = "English",

volume = "13",

pages = "51--54",

journal = "Journal of Animal and Feed Sciences",

issn = "1230-1388",

publisher = "Polska Akademia Nauk Instytut Fizjologii i Zywienia Zwierzat im. Jana Kielanowskiego",

number = "Suppl. 2",

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TY - JOUR

T1 - Effect of vitamins E+C and taurine on the oxidative state of DNA in the liver of growing pigs

AU - Sawosz, E.

AU - Strawa, A.

AU - Chwalibog, Andrzej

AU - Niemiec, T.

AU - Kosieradzka, I.

AU - Dudkowska, I.

PY - 2004

Y1 - 2004

N2 - Growing pigs (n=21)at an initial liveweight of 30 kg were divided into three groups of 7 animals each and housed in individual cages for 100 days. The pigs were fed with similar diets (13.5 MJ ME and 178 g crude protein/kg) but with different additions of vitamins C+E and taurine. The antioxidative vitamins E and C supplied to diets with high energy concentrations (containing lard) can act as pro-oxidants on liver DNA in growing pigs. Taurine decreased the concentration of products from nucleotide oxidation, but in the presence of vitamin E and C, promoted hepatocyte lesions.

AB - Growing pigs (n=21)at an initial liveweight of 30 kg were divided into three groups of 7 animals each and housed in individual cages for 100 days. The pigs were fed with similar diets (13.5 MJ ME and 178 g crude protein/kg) but with different additions of vitamins C+E and taurine. The antioxidative vitamins E and C supplied to diets with high energy concentrations (containing lard) can act as pro-oxidants on liver DNA in growing pigs. Taurine decreased the concentration of products from nucleotide oxidation, but in the presence of vitamin E and C, promoted hepatocyte lesions.

KW - Former LIFE faculty

KW - pigs, vitamin E, vitamin C, taurine, DNA oxidation

M3 - Journal article

SN - 1230-1388

VL - 13

SP - 51

EP - 54

JO - Journal of Animal and Feed Sciences

JF - Journal of Animal and Feed Sciences

IS - Suppl. 2

ER -

Effect of vitamins E+C and taurine on the oxidative state of DNA in the liver of growing pigs

Abstract

Keywords

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