Effect of vitamins E+C and taurine on the oxidative state of DNA in the liver of growing pigs

TY - JOUR

T1 - Effect of vitamins E+C and taurine on the oxidative state of DNA in the liver of growing pigs

AU - Sawosz, E.

AU - Strawa, A.

AU - Chwalibog, Andrzej

AU - Niemiec, T.

AU - Kosieradzka, I.

AU - Dudkowska, I.

PY - 2004

Y1 - 2004

N2 - Growing pigs (n=21)at an initial liveweight of 30 kg were divided into three groups of 7 animals each and housed in individual cages for 100 days. The pigs were fed with similar diets (13.5 MJ ME and 178 g crude protein/kg) but with different additions of vitamins C+E and taurine. The antioxidative vitamins E and C supplied to diets with high energy concentrations (containing lard) can act as pro-oxidants on liver DNA in growing pigs. Taurine decreased the concentration of products from nucleotide oxidation, but in the presence of vitamin E and C, promoted hepatocyte lesions.

AB - Growing pigs (n=21)at an initial liveweight of 30 kg were divided into three groups of 7 animals each and housed in individual cages for 100 days. The pigs were fed with similar diets (13.5 MJ ME and 178 g crude protein/kg) but with different additions of vitamins C+E and taurine. The antioxidative vitamins E and C supplied to diets with high energy concentrations (containing lard) can act as pro-oxidants on liver DNA in growing pigs. Taurine decreased the concentration of products from nucleotide oxidation, but in the presence of vitamin E and C, promoted hepatocyte lesions.

KW - Former LIFE faculty

KW - pigs, vitamin E, vitamin C, taurine, DNA oxidation

M3 - Journal article

SN - 1230-1388

VL - 13

SP - 51

EP - 54

JO - Journal of Animal and Feed Sciences

JF - Journal of Animal and Feed Sciences

IS - Suppl. 2

ER -