Abstract
In the first part important natural products registered as or transformed into registered antimalarial drugs are reviewed together with their mechanisms of action. The mentioned compounds are quinine alkaloids, artemisinin and its derivatives, fosmidomycins, tetracyclines, lincosamide, and naphthoquinones. The latter part is a review of traditional medicines marketed as antimalarial drugs such as Agemone mexicana, Artemisia annua, Artobotrys uncinatus, Cinchona bark, Cryptolepis sanguinolenta, Curcuma longa, and Nauclea probeguinii. Clinical evidence for the effect of the herbal drugs is given.
Original language | English |
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Title of host publication | Evidence-based validation of herbal medicine : Elsevier |
Place of Publication | Amsterdam |
Publication date | 19 Feb 2015 |
Pages | 307-319 |
Chapter | 14 |
ISBN (Electronic) | 978-0-12-800874-4, Mukherje, P. K. |
Publication status | Published - 19 Feb 2015 |