Drugs and drug leads based on natural products for treatment and prophylaxis of malaria

    2 Citations (Scopus)

    Abstract

    In the first part important natural products registered as or transformed into registered antimalarial drugs are reviewed together with their mechanisms of action. The mentioned compounds are quinine alkaloids, artemisinin and its derivatives, fosmidomycins, tetracyclines, lincosamide, and naphthoquinones. The latter part is a review of traditional medicines marketed as antimalarial drugs such as Agemone mexicana, Artemisia annua, Artobotrys uncinatus, Cinchona bark, Cryptolepis sanguinolenta, Curcuma longa, and Nauclea probeguinii. Clinical evidence for the effect of the herbal drugs is given.

    Original languageEnglish
    Title of host publicationEvidence-based validation of herbal medicine : Elsevier
    Place of PublicationAmsterdam
    Publication date19 Feb 2015
    Pages307-319
    Chapter14
    ISBN (Electronic)978-0-12-800874-4, Mukherje, P. K.
    Publication statusPublished - 19 Feb 2015

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