Drugs and drug leads based on natural products for treatment and prophylaxis of malaria

Søren Brøgger Christensen

Drugs and drug leads based on natural products for treatment and prophylaxis of malaria

2 Citationer (Scopus)

Abstract

In the first part important natural products registered as or transformed into registered antimalarial drugs are reviewed together with their mechanisms of action. The mentioned compounds are quinine alkaloids, artemisinin and its derivatives, fosmidomycins, tetracyclines, lincosamide, and naphthoquinones. The latter part is a review of traditional medicines marketed as antimalarial drugs such as Agemone mexicana, Artemisia annua, Artobotrys uncinatus, Cinchona bark, Cryptolepis sanguinolenta, Curcuma longa, and Nauclea probeguinii. Clinical evidence for the effect of the herbal drugs is given.

Originalsprog	Engelsk
Titel	Evidence-based validation of herbal medicine : Elsevier
Udgivelsessted	Amsterdam
Publikationsdato	19 feb. 2015
Sider	307-319
Kapitel	14
ISBN (Elektronisk)	978-0-12-800874-4, Mukherje, P. K.
Status	Udgivet - 19 feb. 2015

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abstract = "In the first part important natural products registered as or transformed into registered antimalarial drugs are reviewed together with their mechanisms of action. The mentioned compounds are quinine alkaloids, artemisinin and its derivatives, fosmidomycins, tetracyclines, lincosamide, and naphthoquinones. The latter part is a review of traditional medicines marketed as antimalarial drugs such as Agemone mexicana, Artemisia annua, Artobotrys uncinatus, Cinchona bark, Cryptolepis sanguinolenta, Curcuma longa, and Nauclea probeguinii. Clinical evidence for the effect of the herbal drugs is given.",

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AB - In the first part important natural products registered as or transformed into registered antimalarial drugs are reviewed together with their mechanisms of action. The mentioned compounds are quinine alkaloids, artemisinin and its derivatives, fosmidomycins, tetracyclines, lincosamide, and naphthoquinones. The latter part is a review of traditional medicines marketed as antimalarial drugs such as Agemone mexicana, Artemisia annua, Artobotrys uncinatus, Cinchona bark, Cryptolepis sanguinolenta, Curcuma longa, and Nauclea probeguinii. Clinical evidence for the effect of the herbal drugs is given.

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Drugs and drug leads based on natural products for treatment and prophylaxis of malaria

Abstract

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