Direct crosslinking of the antitumor antibiotic sparsomycin, and its derivatives, to A2602 in the peptidyl transferase center of 23S-like rRNA within ribosome-tRNA complexes.

B T Porse, S V Kirillov, M J Awayez, H C Ottenheijm, R A Garrett

    47 Citations (Scopus)

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    Keyphrases

    Pharmacology, Toxicology and Pharmaceutical Science

    Biochemistry, Genetics and Molecular Biology