Differential effects of low-intensity motor cortical stimulation on the inspiratory activity in scalene muscles during voluntary and involuntary breathing

Nicolas Caesar Petersen; Janet L Taylor; Nicholas P S Murray; Simon C Gandevia; Jane E Butler

doi:10.1016/j.resp.2010.11.014

Differential effects of low-intensity motor cortical stimulation on the inspiratory activity in scalene muscles during voluntary and involuntary breathing

Nicolas Caesar Petersen, Janet L Taylor, Nicholas P S Murray, Simon C Gandevia, Jane E Butler

14 Citations (Scopus)

Abstract

To assess the cortical contribution to breathing, low-intensity transcranial magnetic stimulation (TMS) was delivered over the motor cortex in 10 subjects during: (i) voluntary static inspiratory efforts, (ii) hypocapnic voluntary ventilation (end-tidal CO(2), 2.7±0.4% mean±SD), and (iii) hypercapnic involuntary ventilation (end-tidal CO(2), 6.0±0.7%). Electromyographic activity (EMG) was recorded from the scalene muscles (obligatory inspiratory muscles) and was significantly suppressed by TMS at short latency (17.2±1.7ms). The scalene EMG was reduced to 76±8% and 76±7% in voluntary breathing and the static inspiratory effort, respectively, but only to 91±10% during the involuntary ventilation, significantly less than during the two voluntary tasks (p

Original language	English
Journal	Respiratory Physiology & Neurobiology
Volume	175
Issue number	2
Pages (from-to)	265-271
Number of pages	7
ISSN	1569-9048
DOIs	https://doi.org/10.1016/j.resp.2010.11.014
Publication status	Published - 15 Feb 2011

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Differential effects of low-intensity motor cortical stimulation on the inspiratory activity in scalene muscles during voluntary and involuntary breathing. / Petersen, Nicolas Caesar; Taylor, Janet L; Murray, Nicholas P S et al.
In: Respiratory Physiology & Neurobiology, Vol. 175, No. 2, 15.02.2011, p. 265-271.

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AU - Taylor, Janet L

AU - Murray, Nicholas P S

AU - Gandevia, Simon C

AU - Butler, Jane E

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Differential effects of low-intensity motor cortical stimulation on the inspiratory activity in scalene muscles during voluntary and involuntary breathing

Abstract

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