Differential effects of low-intensity motor cortical stimulation on the inspiratory activity in scalene muscles during voluntary and involuntary breathing

Nicolas Caesar Petersen; Janet L Taylor; Nicholas P S Murray; Simon C Gandevia; Jane E Butler

doi:10.1016/j.resp.2010.11.014

Differential effects of low-intensity motor cortical stimulation on the inspiratory activity in scalene muscles during voluntary and involuntary breathing

Nicolas Caesar Petersen, Janet L Taylor, Nicholas P S Murray, Simon C Gandevia, Jane E Butler

14 Citationer (Scopus)

Abstract

To assess the cortical contribution to breathing, low-intensity transcranial magnetic stimulation (TMS) was delivered over the motor cortex in 10 subjects during: (i) voluntary static inspiratory efforts, (ii) hypocapnic voluntary ventilation (end-tidal CO(2), 2.7±0.4% mean±SD), and (iii) hypercapnic involuntary ventilation (end-tidal CO(2), 6.0±0.7%). Electromyographic activity (EMG) was recorded from the scalene muscles (obligatory inspiratory muscles) and was significantly suppressed by TMS at short latency (17.2±1.7ms). The scalene EMG was reduced to 76±8% and 76±7% in voluntary breathing and the static inspiratory effort, respectively, but only to 91±10% during the involuntary ventilation, significantly less than during the two voluntary tasks (p

Originalsprog	Engelsk
Tidsskrift	Respiratory Physiology & Neurobiology
Vol/bind	175
Udgave nummer	2
Sider (fra-til)	265-271
Antal sider	7
ISSN	1569-9048
DOI	https://doi.org/10.1016/j.resp.2010.11.014
Status	Udgivet - 15 feb. 2011

Adgang til dokumentet

10.1016/j.resp.2010.11.014

Citationsformater

Differential effects of low-intensity motor cortical stimulation on the inspiratory activity in scalene muscles during voluntary and involuntary breathing. / Petersen, Nicolas Caesar; Taylor, Janet L; Murray, Nicholas P S et al.
I: Respiratory Physiology & Neurobiology, Bind 175, Nr. 2, 15.02.2011, s. 265-271.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

@article{f4600b0f3edc40a19a15688e3ae37464,

title = "Differential effects of low-intensity motor cortical stimulation on the inspiratory activity in scalene muscles during voluntary and involuntary breathing",

abstract = "To assess the cortical contribution to breathing, low-intensity transcranial magnetic stimulation (TMS) was delivered over the motor cortex in 10 subjects during: (i) voluntary static inspiratory efforts, (ii) hypocapnic voluntary ventilation (end-tidal CO(2), 2.7±0.4% mean±SD), and (iii) hypercapnic involuntary ventilation (end-tidal CO(2), 6.0±0.7%). Electromyographic activity (EMG) was recorded from the scalene muscles (obligatory inspiratory muscles) and was significantly suppressed by TMS at short latency (17.2±1.7ms). The scalene EMG was reduced to 76±8% and 76±7% in voluntary breathing and the static inspiratory effort, respectively, but only to 91±10% during the involuntary ventilation, significantly less than during the two voluntary tasks (p",

author = "Petersen, {Nicolas Caesar} and Taylor, {Janet L} and Murray, {Nicholas P S} and Gandevia, {Simon C} and Butler, {Jane E}",

note = "CURIS 2011 5200 030",

year = "2011",

month = feb,

day = "15",

doi = "10.1016/j.resp.2010.11.014",

language = "English",

volume = "175",

pages = "265--271",

journal = "Respiratory Physiology & Neurobiology",

issn = "1569-9048",

publisher = "Elsevier",

number = "2",

}

TY - JOUR

T1 - Differential effects of low-intensity motor cortical stimulation on the inspiratory activity in scalene muscles during voluntary and involuntary breathing

AU - Petersen, Nicolas Caesar

AU - Taylor, Janet L

AU - Murray, Nicholas P S

AU - Gandevia, Simon C

AU - Butler, Jane E

N1 - CURIS 2011 5200 030

PY - 2011/2/15

Y1 - 2011/2/15

N2 - To assess the cortical contribution to breathing, low-intensity transcranial magnetic stimulation (TMS) was delivered over the motor cortex in 10 subjects during: (i) voluntary static inspiratory efforts, (ii) hypocapnic voluntary ventilation (end-tidal CO(2), 2.7±0.4% mean±SD), and (iii) hypercapnic involuntary ventilation (end-tidal CO(2), 6.0±0.7%). Electromyographic activity (EMG) was recorded from the scalene muscles (obligatory inspiratory muscles) and was significantly suppressed by TMS at short latency (17.2±1.7ms). The scalene EMG was reduced to 76±8% and 76±7% in voluntary breathing and the static inspiratory effort, respectively, but only to 91±10% during the involuntary ventilation, significantly less than during the two voluntary tasks (p

AB - To assess the cortical contribution to breathing, low-intensity transcranial magnetic stimulation (TMS) was delivered over the motor cortex in 10 subjects during: (i) voluntary static inspiratory efforts, (ii) hypocapnic voluntary ventilation (end-tidal CO(2), 2.7±0.4% mean±SD), and (iii) hypercapnic involuntary ventilation (end-tidal CO(2), 6.0±0.7%). Electromyographic activity (EMG) was recorded from the scalene muscles (obligatory inspiratory muscles) and was significantly suppressed by TMS at short latency (17.2±1.7ms). The scalene EMG was reduced to 76±8% and 76±7% in voluntary breathing and the static inspiratory effort, respectively, but only to 91±10% during the involuntary ventilation, significantly less than during the two voluntary tasks (p

U2 - 10.1016/j.resp.2010.11.014

DO - 10.1016/j.resp.2010.11.014

M3 - Journal article

C2 - 21138775

SN - 1569-9048

VL - 175

SP - 265

EP - 271

JO - Respiratory Physiology & Neurobiology

JF - Respiratory Physiology & Neurobiology

IS - 2

ER -

Differential effects of low-intensity motor cortical stimulation on the inspiratory activity in scalene muscles during voluntary and involuntary breathing

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater