Diastereomeric ratio determination by high sensitivity band-selective pure shift NMR spectroscopy

Ralph W. Adams; Liam Byrne; Peter Kiraly; Mohammadali Foroozandeh; Liladhar Paudel; Lars Mathias Nilsson; Jonathan Clayden; Gareth A. Morris

doi:10.1039/c3cc49659g

Diastereomeric ratio determination by high sensitivity band-selective pure shift NMR spectroscopy

Ralph W. Adams, Liam Byrne, Peter Kiraly, Mohammadali Foroozandeh, Liladhar Paudel, Lars Mathias Nilsson, Jonathan Clayden, Gareth A. Morris

Food Analytics and Biotechnology

57 Citations (Scopus)

Abstract

An NMR method is reported that allows diastereomeric ratios to be determined even in crowded spectra or where chemical shift differences are small compared to multiplet widths. Band-selective pure shift NMR collapses multiplets to singlets, greatly improving spectral resolution while largely retaining, or even enhancing, signal-to-noise ratio.

Original language	English
Journal	Chemical Communications
Volume	50
Issue number	19
Pages (from-to)	2512-2514
Number of pages	3
ISSN	1359-7345
DOIs	https://doi.org/10.1039/c3cc49659g
Publication status	Published - 7 Feb 2014

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title = "Diastereomeric ratio determination by high sensitivity band-selective pure shift NMR spectroscopy",

abstract = "An NMR method is reported that allows diastereomeric ratios to be determined even in crowded spectra or where chemical shift differences are small compared to multiplet widths. Band-selective pure shift NMR collapses multiplets to singlets, greatly improving spectral resolution while largely retaining, or even enhancing, signal-to-noise ratio.",

author = "Adams, {Ralph W.} and Liam Byrne and Peter Kiraly and Mohammadali Foroozandeh and Liladhar Paudel and Nilsson, {Lars Mathias} and Jonathan Clayden and Morris, {Gareth A.}",

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AU - Adams, Ralph W.

AU - Byrne, Liam

AU - Kiraly, Peter

AU - Foroozandeh, Mohammadali

AU - Paudel, Liladhar

AU - Nilsson, Lars Mathias

AU - Clayden, Jonathan

AU - Morris, Gareth A.

PY - 2014/2/7

Y1 - 2014/2/7

N2 - An NMR method is reported that allows diastereomeric ratios to be determined even in crowded spectra or where chemical shift differences are small compared to multiplet widths. Band-selective pure shift NMR collapses multiplets to singlets, greatly improving spectral resolution while largely retaining, or even enhancing, signal-to-noise ratio.

AB - An NMR method is reported that allows diastereomeric ratios to be determined even in crowded spectra or where chemical shift differences are small compared to multiplet widths. Band-selective pure shift NMR collapses multiplets to singlets, greatly improving spectral resolution while largely retaining, or even enhancing, signal-to-noise ratio.

U2 - 10.1039/c3cc49659g

DO - 10.1039/c3cc49659g

M3 - Journal article

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SN - 1359-7345

VL - 50

SP - 2512

EP - 2514

JO - Chemical Communications

JF - Chemical Communications

IS - 19

ER -

Diastereomeric ratio determination by high sensitivity band-selective pure shift NMR spectroscopy

Abstract

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