Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells

P T Schmidt; B Hartmann; S Bregenholt; Jens Juul Holst; Mogens Helweg Claesson

Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells

P T Schmidt, B Hartmann, S Bregenholt, Jens Juul Holst, Mogens Helweg Claesson

25 Citations (Scopus)

Abstract

Glucagon-like peptide 2 (GLP-2) is produced in endocrine L-cells of the intestinal mucosa. Recently, GLP-2 was found to stimulate intestinal mucosal growth. Our objective was to study the content of GLP-2 in the large intestine in a murine model of T-cell-induced inflammatory bowel disease.

Original language	English
Journal	Scandinavian Journal of Gastroenterology
Volume	35
Issue number	5
Pages (from-to)	522-7
Number of pages	6
ISSN	0036-5521
Publication status	Published - 1 May 2000

Keywords

Animals
CD4-Positive T-Lymphocytes
Colon
Disease Models, Animal
Glucagon
Glucagon-Like Peptide 2
Glucagon-Like Peptides
Growth Substances
Inflammatory Bowel Diseases
Mice
Mice, SCID
Peptide Fragments

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Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells. / Schmidt, P T; Hartmann, B; Bregenholt, S et al.

In: Scandinavian Journal of Gastroenterology, Vol. 35, No. 5, 01.05.2000, p. 522-7.

Research output: Contribution to journal › Journal article › Research › peer-review

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AU - Holst, Jens Juul

AU - Claesson, Mogens Helweg

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KW - CD4-Positive T-Lymphocytes

KW - Colon

KW - Disease Models, Animal

KW - Glucagon

KW - Glucagon-Like Peptide 2

KW - Glucagon-Like Peptides

KW - Growth Substances

KW - Inflammatory Bowel Diseases

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KW - Peptide Fragments

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JO - Scandinavian Journal of Gastroenterology

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ER -

Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells

Abstract

Keywords

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