Defective monocyte function in Legionnaires' disease complicating hairy cell leukaemia

H Nielsen, Jette Marie Bangsborg, C Rechnitzer, N Jacobsen, Hans Busk

12 Citations (Scopus)

Abstract

We describe a case of Legionnaires' disease in a 64-year-old man, in which hairy cell leukaemia was diagnosed after the onset of the infection. Immunological studies revealed a complete suppression of blood monocyte chemotactic and oxidative burst activities. We suggest that in hairy cell leukaemia both monocytopenia and defective functions of monocytes underlie the increased susceptibility to intracellular infections including Legionnaires' disease.
Original languageEnglish
JournalACTA MEDICA SCANDINAVICA
Volume220
Issue number4
Pages (from-to)381-3
Number of pages3
ISSN0001-6101
Publication statusPublished - 1986

Keywords

  • Diabetes Mellitus, Type 2
  • Humans
  • Legionnaires' Disease
  • Leukemia, Hairy Cell
  • Male
  • Middle Aged
  • Monocytes

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