Cross-species ChIP-seq studies provide insights into regulatory strategies of PPAR¿ in adipocytes

Søren Fisker Schmidt; Mette Jørgensen; Albin Gustav Sandelin; Susanne Mandrup

doi:10.4161/trns.3.1.19302

Cross-species ChIP-seq studies provide insights into regulatory strategies of PPAR¿ in adipocytes

Søren Fisker Schmidt, Mette Jørgensen, Albin Gustav Sandelin, Susanne Mandrup

Computational and RNA Biology

5 Citations (Scopus)

Abstract

Three recent studies have investigated interspecies retention of binding sites of peroxisome proliferator-activated receptor γ (PPARγ), the master regulator of adipocyte differention, between mouse and human adipocytes. Here we discuss the major findings and demonstrate that retention of binding events is highly context-dependent.

Original language	English
Book series	Transcription
Volume	3
Issue number	1
Pages (from-to)	19-24
Number of pages	6
ISSN	1613-8414
DOIs	https://doi.org/10.4161/trns.3.1.19302
Publication status	Published - 2012

Access to Document

10.4161/trns.3.1.19302

Cite this

@article{0f3efbba4e96495ba2df27b98cb6d868,

title = "Cross-species ChIP-seq studies provide insights into regulatory strategies of PPAR¿ in adipocytes",

abstract = "Three recent studies have investigated interspecies retention of binding sites of peroxisome proliferator-activated receptor γ (PPARγ), the master regulator of adipocyte differention, between mouse and human adipocytes. Here we discuss the major findings and demonstrate that retention of binding events is highly context-dependent.",

author = "Schmidt, {S{\o}ren Fisker} and Mette J{\o}rgensen and Sandelin, {Albin Gustav} and Susanne Mandrup",

year = "2012",

doi = "10.4161/trns.3.1.19302",

language = "English",

volume = "3",

pages = "19--24",

journal = "Transcription",

issn = "1613-8414",

publisher = "PeterLang GmbH",

number = "1",

}

TY - JOUR

T1 - Cross-species ChIP-seq studies provide insights into regulatory strategies of PPAR¿ in adipocytes

AU - Schmidt, Søren Fisker

AU - Jørgensen, Mette

AU - Sandelin, Albin Gustav

AU - Mandrup, Susanne

PY - 2012

Y1 - 2012

N2 - Three recent studies have investigated interspecies retention of binding sites of peroxisome proliferator-activated receptor γ (PPARγ), the master regulator of adipocyte differention, between mouse and human adipocytes. Here we discuss the major findings and demonstrate that retention of binding events is highly context-dependent.

AB - Three recent studies have investigated interspecies retention of binding sites of peroxisome proliferator-activated receptor γ (PPARγ), the master regulator of adipocyte differention, between mouse and human adipocytes. Here we discuss the major findings and demonstrate that retention of binding events is highly context-dependent.

U2 - 10.4161/trns.3.1.19302

DO - 10.4161/trns.3.1.19302

M3 - Journal article

C2 - 22456316

SN - 1613-8414

VL - 3

SP - 19

EP - 24

JO - Transcription

JF - Transcription

IS - 1

ER -

Cross-species ChIP-seq studies provide insights into regulatory strategies of PPAR¿ in adipocytes

Abstract

Access to Document

Fingerprint

Cite this