Cross-species ChIP-seq studies provide insights into regulatory strategies of PPAR¿ in adipocytes

Søren Fisker Schmidt; Mette Jørgensen; Albin Gustav Sandelin; Susanne Mandrup

doi:10.4161/trns.3.1.19302

Cross-species ChIP-seq studies provide insights into regulatory strategies of PPAR¿ in adipocytes

Søren Fisker Schmidt, Mette Jørgensen, Albin Gustav Sandelin, Susanne Mandrup

Bioinformatik og RNA Biologi

5 Citationer (Scopus)

Abstract

Three recent studies have investigated interspecies retention of binding sites of peroxisome proliferator-activated receptor γ (PPARγ), the master regulator of adipocyte differention, between mouse and human adipocytes. Here we discuss the major findings and demonstrate that retention of binding events is highly context-dependent.

Originalsprog	Engelsk
Bogserie	Transcription
Vol/bind	3
Udgave nummer	1
Sider (fra-til)	19-24
Antal sider	6
ISSN	1613-8414
DOI	https://doi.org/10.4161/trns.3.1.19302
Status	Udgivet - 2012

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10.4161/trns.3.1.19302

Citationsformater

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DO - 10.4161/trns.3.1.19302

M3 - Journal article

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SN - 1613-8414

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JO - Transcription

JF - Transcription

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Cross-species ChIP-seq studies provide insights into regulatory strategies of PPAR¿ in adipocytes

Abstract

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