Abstract
In order to deduce the primary structure of bovine preprogastrin we therefore sequenced a gastrin DNA clone isolated from a bovine liver cosmid library. Bovine preprogastrin comprises 104 amino acids and consists of a signal peptide, a 37 amino acid spacer-sequence, the gastrin-34 sequence followed by an amidation-site (Gly-Arg-Arg), and a C-terminal nonapeptide. Comparison with human, porcine, and rat cDNA sequences revealed extensive homology in the coding region as well as in short noncoding structures.
| Original language | English |
|---|---|
| Journal | Molecular Endocrinology |
| Volume | 3 |
| Issue number | 10 |
| Pages (from-to) | 1585-8 |
| Number of pages | 3 |
| ISSN | 0888-8809 |
| Publication status | Published - 1989 |