Circulating serum trefoil factors increase dramatically during pregnancy

Mie Hessellund Samson; E M Vestergaard; N Milman; Steen Seier Poulsen; E Nexo

doi:10.1080/00365510701767862

Circulating serum trefoil factors increase dramatically during pregnancy

Mie Hessellund Samson, E M Vestergaard, N Milman, Steen Seier Poulsen, E Nexo

Endocrinology and Metabolism

20 Citations (Scopus)

Abstract

Trefoil factors (TFF1-3) are 7-12 kDa peptides secreted by mucosal surfaces, with changing levels of expression reflected in serum concentrations. The genes for the peptides are located on chromosome 21, the chromosome duplicated in trisomy 21. We studied the levels of circulating TFFs in pregnant women carrying trisomy 21 foetuses and in women with normal pregnancies, throughout pregnancy and postpartum.

Original language	English
Journal	Scandinavian Journal of Clinical & Laboratory Investigation
Volume	68
Issue number	5
Pages (from-to)	369-374
Number of pages	6
ISSN	0036-5513
DOIs	https://doi.org/10.1080/00365510701767862
Publication status	Published - 2008

Keywords

Adenosine Triphosphatases
Chromatography, Gel
DNA-Binding Proteins
Female
Humans
Peptides
Pregnancy
Transcription Factors
Trisomy

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10.1080/00365510701767862

Cite this

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abstract = "Trefoil factors (TFF1-3) are 7-12 kDa peptides secreted by mucosal surfaces, with changing levels of expression reflected in serum concentrations. The genes for the peptides are located on chromosome 21, the chromosome duplicated in trisomy 21. We studied the levels of circulating TFFs in pregnant women carrying trisomy 21 foetuses and in women with normal pregnancies, throughout pregnancy and postpartum.",

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AU - Samson, Mie Hessellund

AU - Vestergaard, E M

AU - Milman, N

AU - Poulsen, Steen Seier

AU - Nexo, E

PY - 2008

Y1 - 2008

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AB - Trefoil factors (TFF1-3) are 7-12 kDa peptides secreted by mucosal surfaces, with changing levels of expression reflected in serum concentrations. The genes for the peptides are located on chromosome 21, the chromosome duplicated in trisomy 21. We studied the levels of circulating TFFs in pregnant women carrying trisomy 21 foetuses and in women with normal pregnancies, throughout pregnancy and postpartum.

KW - Adenosine Triphosphatases

KW - Chromatography, Gel

KW - DNA-Binding Proteins

KW - Female

KW - Humans

KW - Peptides

KW - Pregnancy

KW - Transcription Factors

KW - Trisomy

U2 - 10.1080/00365510701767862

DO - 10.1080/00365510701767862

M3 - Journal article

C2 - 19172695

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JO - Scandinavian Journal of Clinical & Laboratory Investigation

JF - Scandinavian Journal of Clinical & Laboratory Investigation

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ER -

Circulating serum trefoil factors increase dramatically during pregnancy

Abstract

Keywords

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