Circulating serum trefoil factors increase dramatically during pregnancy

Mie Hessellund Samson; E M Vestergaard; N Milman; Steen Seier Poulsen; E Nexo

doi:10.1080/00365510701767862

Circulating serum trefoil factors increase dramatically during pregnancy

Mie Hessellund Samson, E M Vestergaard, N Milman, Steen Seier Poulsen, E Nexo

Endocrinology and Metabolism

20 Citationer (Scopus)

Abstract

Trefoil factors (TFF1-3) are 7-12 kDa peptides secreted by mucosal surfaces, with changing levels of expression reflected in serum concentrations. The genes for the peptides are located on chromosome 21, the chromosome duplicated in trisomy 21. We studied the levels of circulating TFFs in pregnant women carrying trisomy 21 foetuses and in women with normal pregnancies, throughout pregnancy and postpartum.

Originalsprog	Engelsk
Tidsskrift	Scandinavian Journal of Clinical & Laboratory Investigation
Vol/bind	68
Udgave nummer	5
Sider (fra-til)	369-374
Antal sider	6
ISSN	0036-5513
DOI	https://doi.org/10.1080/00365510701767862
Status	Udgivet - 2008

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10.1080/00365510701767862

Citationsformater

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abstract = "Trefoil factors (TFF1-3) are 7-12 kDa peptides secreted by mucosal surfaces, with changing levels of expression reflected in serum concentrations. The genes for the peptides are located on chromosome 21, the chromosome duplicated in trisomy 21. We studied the levels of circulating TFFs in pregnant women carrying trisomy 21 foetuses and in women with normal pregnancies, throughout pregnancy and postpartum.",

keywords = "Adenosine Triphosphatases, Chromatography, Gel, DNA-Binding Proteins, Female, Humans, Peptides, Pregnancy, Transcription Factors, Trisomy",

author = "Samson, {Mie Hessellund} and Vestergaard, {E M} and N Milman and Poulsen, {Steen Seier} and E Nexo",

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AU - Samson, Mie Hessellund

AU - Vestergaard, E M

AU - Milman, N

AU - Poulsen, Steen Seier

AU - Nexo, E

PY - 2008

Y1 - 2008

N2 - Trefoil factors (TFF1-3) are 7-12 kDa peptides secreted by mucosal surfaces, with changing levels of expression reflected in serum concentrations. The genes for the peptides are located on chromosome 21, the chromosome duplicated in trisomy 21. We studied the levels of circulating TFFs in pregnant women carrying trisomy 21 foetuses and in women with normal pregnancies, throughout pregnancy and postpartum.

AB - Trefoil factors (TFF1-3) are 7-12 kDa peptides secreted by mucosal surfaces, with changing levels of expression reflected in serum concentrations. The genes for the peptides are located on chromosome 21, the chromosome duplicated in trisomy 21. We studied the levels of circulating TFFs in pregnant women carrying trisomy 21 foetuses and in women with normal pregnancies, throughout pregnancy and postpartum.

KW - Adenosine Triphosphatases

KW - Chromatography, Gel

KW - DNA-Binding Proteins

KW - Female

KW - Humans

KW - Peptides

KW - Pregnancy

KW - Transcription Factors

KW - Trisomy

U2 - 10.1080/00365510701767862

DO - 10.1080/00365510701767862

M3 - Journal article

C2 - 19172695

SN - 0036-5513

VL - 68

SP - 369

EP - 374

JO - Scandinavian Journal of Clinical & Laboratory Investigation

JF - Scandinavian Journal of Clinical & Laboratory Investigation

IS - 5

ER -

Circulating serum trefoil factors increase dramatically during pregnancy

Abstract

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