Chronic obstructive pulmonary disease and genetics

T. Ingebrigtsen; S.F. Thomsen; J. Vestbo; V. Backer

Chronic obstructive pulmonary disease and genetics

T. Ingebrigtsen, S.F. Thomsen, J. Vestbo, V. Backer

Abstract

Chronic obstructive pulmonary disease (COPD) is characterised by airflow limitation and is associated with an inflammatory response of the lungs primarily caused by cigarette smoking. Cigarette smoking is by far the most important environmental risk factor for COPD, but less than half of all heavy smokers develop COPD. This indicates a genetic contribution to the individual disease susceptibility. Although many genes have been examined, the puzzle of COPD genetics seems still largely unsolved. It is therefore important to measure phenotypes and to perform genome-wide scans of COPD patients in order to unravel the contribution of the COPD susceptibility genes
Udgivelsesdato: 2008/9/15

Original language	Danish
Journal	Ugeskrift for læger
Volume	170
Issue number	38
Pages (from-to)	2971-2973
Number of pages	2
ISSN	0041-5782
Publication status	Published - 2008

Cite this

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title = "Chronic obstructive pulmonary disease and genetics",

abstract = "Chronic obstructive pulmonary disease (COPD) is characterised by airflow limitation and is associated with an inflammatory response of the lungs primarily caused by cigarette smoking. Cigarette smoking is by far the most important environmental risk factor for COPD, but less than half of all heavy smokers develop COPD. This indicates a genetic contribution to the individual disease susceptibility. Although many genes have been examined, the puzzle of COPD genetics seems still largely unsolved. It is therefore important to measure phenotypes and to perform genome-wide scans of COPD patients in order to unravel the contribution of the COPD susceptibility genes Udgivelsesdato: 2008/9/15",

author = "T. Ingebrigtsen and S.F. Thomsen and J. Vestbo and V. Backer",

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T1 - Chronic obstructive pulmonary disease and genetics

AU - Ingebrigtsen, T.

AU - Thomsen, S.F.

AU - Vestbo, J.

AU - Backer, V.

PY - 2008

Y1 - 2008

N2 - Chronic obstructive pulmonary disease (COPD) is characterised by airflow limitation and is associated with an inflammatory response of the lungs primarily caused by cigarette smoking. Cigarette smoking is by far the most important environmental risk factor for COPD, but less than half of all heavy smokers develop COPD. This indicates a genetic contribution to the individual disease susceptibility. Although many genes have been examined, the puzzle of COPD genetics seems still largely unsolved. It is therefore important to measure phenotypes and to perform genome-wide scans of COPD patients in order to unravel the contribution of the COPD susceptibility genes Udgivelsesdato: 2008/9/15

AB - Chronic obstructive pulmonary disease (COPD) is characterised by airflow limitation and is associated with an inflammatory response of the lungs primarily caused by cigarette smoking. Cigarette smoking is by far the most important environmental risk factor for COPD, but less than half of all heavy smokers develop COPD. This indicates a genetic contribution to the individual disease susceptibility. Although many genes have been examined, the puzzle of COPD genetics seems still largely unsolved. It is therefore important to measure phenotypes and to perform genome-wide scans of COPD patients in order to unravel the contribution of the COPD susceptibility genes Udgivelsesdato: 2008/9/15

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 170

SP - 2971

EP - 2973

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 38

ER -