Chronic obstructive pulmonary disease and genetics

T. Ingebrigtsen, S.F. Thomsen, J. Vestbo, V. Backer

    Abstract

    Chronic obstructive pulmonary disease (COPD) is characterised by airflow limitation and is associated with an inflammatory response of the lungs primarily caused by cigarette smoking. Cigarette smoking is by far the most important environmental risk factor for COPD, but less than half of all heavy smokers develop COPD. This indicates a genetic contribution to the individual disease susceptibility. Although many genes have been examined, the puzzle of COPD genetics seems still largely unsolved. It is therefore important to measure phenotypes and to perform genome-wide scans of COPD patients in order to unravel the contribution of the COPD susceptibility genes
    Udgivelsesdato: 2008/9/15
    OriginalsprogDansk
    TidsskriftUgeskrift for læger
    Vol/bind170
    Udgave nummer38
    Sider (fra-til)2971-2973
    Antal sider2
    ISSN0041-5782
    StatusUdgivet - 2008

    Citationsformater