Changes in the repertoire of natural antibodies caused by immunization with bacterial antigens

N V Shilova; M J Navakouski; M Huflejt; A Kuehn; R Grunow; Klas Ola Blixt; N V Bovin

doi:10.1134/s0006297911070170

Changes in the repertoire of natural antibodies caused by immunization with bacterial antigens

N V Shilova, M J Navakouski, M Huflejt, A Kuehn, R Grunow, Klas Ola Blixt, N V Bovin

Glycomics Program

5 Citations (Scopus)

Abstract

The repertoire of natural anti-glycan antibodies in naive chickens and in chickens immunized with bacteria Burkholderia mallei, Burkholderia pseudomallei, and Francisella tularensis as well as with peptides from an outer membrane protein of B. pseudomallei was studied. A relatively restricted pattern of natural antibodies (first of all IgY against bacterial cell wall peptidoglycan fragments, L-Rha, and core N-acetyllactosamine) shrank and, moreover, the level of detectable antibodies decreased as a result of immunization.

Original language	English
Journal	Biochemistry. Biokhimii¿a
Volume	76
Issue number	7
Pages (from-to)	862-6
Number of pages	5
DOIs	https://doi.org/10.1134/s0006297911070170
Publication status	Published - Jul 2011

Keywords

Animals
Antigens, Bacterial
Bacterial Outer Membrane Proteins
Burkholderia mallei
Burkholderia pseudomallei
Carbohydrate Sequence
Chickens
Francisella tularensis
Immunity, Innate
Immunization
Immunoglobulins
Molecular Sequence Data

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title = "Changes in the repertoire of natural antibodies caused by immunization with bacterial antigens",

abstract = "The repertoire of natural anti-glycan antibodies in naive chickens and in chickens immunized with bacteria Burkholderia mallei, Burkholderia pseudomallei, and Francisella tularensis as well as with peptides from an outer membrane protein of B. pseudomallei was studied. A relatively restricted pattern of natural antibodies (first of all IgY against bacterial cell wall peptidoglycan fragments, L-Rha, and core N-acetyllactosamine) shrank and, moreover, the level of detectable antibodies decreased as a result of immunization.",

keywords = "Animals, Antigens, Bacterial, Bacterial Outer Membrane Proteins, Burkholderia mallei, Burkholderia pseudomallei, Carbohydrate Sequence, Chickens, Francisella tularensis, Immunity, Innate, Immunization, Immunoglobulins, Molecular Sequence Data",

author = "Shilova, {N V} and Navakouski, {M J} and M Huflejt and A Kuehn and R Grunow and Blixt, {Klas Ola} and Bovin, {N V}",

year = "2011",

month = jul,

doi = "10.1134/s0006297911070170",

language = "English",

volume = "76",

pages = "862--6",

journal = "Biochemistry (Moscow)",

issn = "0006-2979",

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T1 - Changes in the repertoire of natural antibodies caused by immunization with bacterial antigens

AU - Shilova, N V

AU - Navakouski, M J

AU - Huflejt, M

AU - Kuehn, A

AU - Grunow, R

AU - Blixt, Klas Ola

AU - Bovin, N V

PY - 2011/7

Y1 - 2011/7

N2 - The repertoire of natural anti-glycan antibodies in naive chickens and in chickens immunized with bacteria Burkholderia mallei, Burkholderia pseudomallei, and Francisella tularensis as well as with peptides from an outer membrane protein of B. pseudomallei was studied. A relatively restricted pattern of natural antibodies (first of all IgY against bacterial cell wall peptidoglycan fragments, L-Rha, and core N-acetyllactosamine) shrank and, moreover, the level of detectable antibodies decreased as a result of immunization.

AB - The repertoire of natural anti-glycan antibodies in naive chickens and in chickens immunized with bacteria Burkholderia mallei, Burkholderia pseudomallei, and Francisella tularensis as well as with peptides from an outer membrane protein of B. pseudomallei was studied. A relatively restricted pattern of natural antibodies (first of all IgY against bacterial cell wall peptidoglycan fragments, L-Rha, and core N-acetyllactosamine) shrank and, moreover, the level of detectable antibodies decreased as a result of immunization.

KW - Animals

KW - Antigens, Bacterial

KW - Bacterial Outer Membrane Proteins

KW - Burkholderia mallei

KW - Burkholderia pseudomallei

KW - Carbohydrate Sequence

KW - Chickens

KW - Francisella tularensis

KW - Immunity, Innate

KW - Immunization

KW - Immunoglobulins

KW - Molecular Sequence Data

U2 - 10.1134/s0006297911070170

DO - 10.1134/s0006297911070170

M3 - Journal article

C2 - 21999548

SN - 0006-2979

VL - 76

SP - 862

EP - 866

JO - Biochemistry (Moscow)

JF - Biochemistry (Moscow)

IS - 7

ER -

Changes in the repertoire of natural antibodies caused by immunization with bacterial antigens

Abstract

Keywords

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