Changes in the insulin-like growth factor-system may contribute to in vitro age-related impaired osteoblast functions.

Medicine & Life Sciences

• Somatomedins 100%
• Osteoblasts 89%
• Insulin-Like Growth Factor Binding Protein 4 48%
• In Vitro Techniques 41%
• Insulin-Like Growth Factor Binding Proteins 30%
• Insulin-Like Growth Factor Binding Protein 5 24%
• Insulin-Like Growth Factor Binding Protein 3 19%
• Peptide Hydrolases 19%
• Insulin-Like Growth Factor II 19%
• Messenger RNA 17%
• Insulin-Like Growth Factor I 15%
• Proteins 11%
• Ligands 11%
• Western Blotting 10%
• Diploidy 8%
• Cancellous Bone 8%
• Conditioned Culture Medium 8%
• Reverse Transcriptase Polymerase Chain Reaction 7%
• Protein Binding 7%
• Northern Blotting 7%
• Osteoporosis 6%
• Osteogenesis 6%
• Gene Expression 4%
• Cell Line 4%

Chemical Compounds

• Insulin-Like Growth Factor II 51%
• Insulin-Like Growth Factor I 48%
• Protein 38%
• Conditioned Culture Medium 23%
• Ligand 13%