BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity

Rikke D. Rasmussen; Madhavsai K. Gajjar; Lucie Tuckova; Kamilla E Jensen; Apolinar Maya-Mendoza; Camilla B. Holst; Kjeld Mollgaard; Jane S. Rasmussen; Jannick Brennum; Jiri, Jr. Bartek; Martin Syrucek; Eva Sedlakova; Klaus K. Andersen; Marie H. Frederiksen; Jiri Bartek; Petra Hamerlik

doi:10.1038/ncomms13398

BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity

Rikke D. Rasmussen, Madhavsai K. Gajjar, Lucie Tuckova, Kamilla E Jensen, Apolinar Maya-Mendoza, Camilla B. Holst, Kjeld Mollgaard, Jane S. Rasmussen, Jannick Brennum, Jiri, Jr. Bartek, Martin Syrucek, Eva Sedlakova, Klaus K. Andersen, Marie H. Frederiksen, Jiri Bartek, Petra Hamerlik

Morphogenesis and Differentiation Program

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Original language	English
Article number	13398
Journal	Nature Communications
Volume	7
ISSN	2041-1723
DOIs	https://doi.org/10.1038/ncomms13398
Publication status	Published - 15 Nov 2016

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BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicityLicence: CC BY

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Rasmussen, R. D., Gajjar, M. K., Tuckova, L., Jensen, K. E., Maya-Mendoza, A., Holst, C. B., Mollgaard, K., Rasmussen, J. S., Brennum, J., Bartek, J. J., Syrucek, M., Sedlakova, E., Andersen, K. K., Frederiksen, M. H., Bartek, J., & Hamerlik, P. (2016). BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity. Nature Communications, 7, Article 13398. https://doi.org/10.1038/ncomms13398

Rasmussen, RD, Gajjar, MK, Tuckova, L, Jensen, KE, Maya-Mendoza, A, Holst, CB , Mollgaard, K, Rasmussen, JS, Brennum, J, Bartek, JJ, Syrucek, M, Sedlakova, E, Andersen, KK, Frederiksen, MH, Bartek, J & Hamerlik, P 2016, 'BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity', Nature Communications, vol. 7, 13398. https://doi.org/10.1038/ncomms13398

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title = "BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity",

author = "Rasmussen, {Rikke D.} and Gajjar, {Madhavsai K.} and Lucie Tuckova and Jensen, {Kamilla E} and Apolinar Maya-Mendoza and Holst, {Camilla B.} and Kjeld Mollgaard and Rasmussen, {Jane S.} and Jannick Brennum and Bartek, {Jiri, Jr.} and Martin Syrucek and Eva Sedlakova and Andersen, {Klaus K.} and Frederiksen, {Marie H.} and Jiri Bartek and Petra Hamerlik",

year = "2016",

month = nov,

day = "15",

doi = "10.1038/ncomms13398",

language = "English",

volume = "7",

journal = "Nature Communications",

issn = "2041-1723",

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T1 - BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity

AU - Rasmussen, Rikke D.

AU - Gajjar, Madhavsai K.

AU - Tuckova, Lucie

AU - Jensen, Kamilla E

AU - Maya-Mendoza, Apolinar

AU - Holst, Camilla B.

AU - Mollgaard, Kjeld

AU - Rasmussen, Jane S.

AU - Brennum, Jannick

AU - Bartek, Jiri, Jr.

AU - Syrucek, Martin

AU - Sedlakova, Eva

AU - Andersen, Klaus K.

AU - Frederiksen, Marie H.

AU - Bartek, Jiri

AU - Hamerlik, Petra

PY - 2016/11/15

Y1 - 2016/11/15

UR - https://www.nature.com/articles/s41467-018-07892-6

U2 - 10.1038/ncomms13398

DO - 10.1038/ncomms13398

M3 - Journal article

C2 - 27845331

SN - 2041-1723

VL - 7

JO - Nature Communications

JF - Nature Communications

M1 - 13398

ER -

BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity

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