Biosynthesis of Tcr-alpha, beta and Tcr-gamma, delta/CD3 complexes

TY - JOUR

T1 - Biosynthesis of Tcr-alpha, beta and Tcr-gamma, delta/CD3 complexes

AU - Bauguil-Caspar, S

AU - Arnaud, J

AU - Kuhlmann, J

AU - Geisler, C

AU - Rubin, B

N1 - Keywords: Amino Acid Sequence; Animals; Antigens, CD3; Clone Cells; Conserved Sequence; DNA, Complementary; Humans; Molecular Sequence Data; Point Mutation; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta; Sequence Homology, Amino Acid; Transfection

PY - 1993

Y1 - 1993

N2 - Jurkat J76 clone, LYON L12.37 clone and L12.37 cells transfected with J76-alpha cDNA or J76 Tcr-alpha mutated cDNA (J79) were analysed for membrane expression of Tcr/CD3 complex using WT31 mAb (Tcr-alpha, beta) or Tcr-delta 1 mAb (Tcr-gamma, delta): LYON cells express V beta 9 bearing Tcr-beta chains. J76 Tcr-alpha cDNA transfected LYON cells have intracellular Tcr-gamma, delta chains and J79 Tcr-alpha cDNA transfected LYON cells have intracellular Tcr-alpha (M), beta chains.

AB - Jurkat J76 clone, LYON L12.37 clone and L12.37 cells transfected with J76-alpha cDNA or J76 Tcr-alpha mutated cDNA (J79) were analysed for membrane expression of Tcr/CD3 complex using WT31 mAb (Tcr-alpha, beta) or Tcr-delta 1 mAb (Tcr-gamma, delta): LYON cells express V beta 9 bearing Tcr-beta chains. J76 Tcr-alpha cDNA transfected LYON cells have intracellular Tcr-gamma, delta chains and J79 Tcr-alpha cDNA transfected LYON cells have intracellular Tcr-alpha (M), beta chains.

M3 - Journal article

C2 - 8167683

SN - 1067-795X

VL - 4

SP - 113

EP - 116

JO - Immunodeficiency

JF - Immunodeficiency

IS - 1-4

ER -