Biosynthesis of glucosinolates - gene discovery and beyond

TY - JOUR

T1 - Biosynthesis of glucosinolates - gene discovery and beyond

AU - Sønderby, Ida Elken

AU - Geu Flores, Fernando

AU - Halkier, Barbara Ann

PY - 2010/5

Y1 - 2010/5

N2 - Glucosinolates are sulfur-rich secondary metabolites characteristic of the Brassicales order with important biological and economic roles in plant defense and human nutrition. Application of systems biology tools continues to identify genes involved in the biosynthesis of glucosinolates. Recent progress includes genes in all three phases of the pathway, i.e. side-chain elongation of precursor amino acids, formation of the core glucosinolate structure and side-chain decoration. Major breakthroughs include the ability to produce glucosinolates in Nicotiana benthamiana, the finding that specific glucosinolates play a key role in Arabidopsis innate immune response, and a better understanding of the link between primary sulfur metabolism and glucosinolate biosynthesis.

AB - Glucosinolates are sulfur-rich secondary metabolites characteristic of the Brassicales order with important biological and economic roles in plant defense and human nutrition. Application of systems biology tools continues to identify genes involved in the biosynthesis of glucosinolates. Recent progress includes genes in all three phases of the pathway, i.e. side-chain elongation of precursor amino acids, formation of the core glucosinolate structure and side-chain decoration. Major breakthroughs include the ability to produce glucosinolates in Nicotiana benthamiana, the finding that specific glucosinolates play a key role in Arabidopsis innate immune response, and a better understanding of the link between primary sulfur metabolism and glucosinolate biosynthesis.

U2 - 10.1016/j.tplants.2010.02.005

DO - 10.1016/j.tplants.2010.02.005

M3 - Journal article

SN - 1360-1385

VL - 15

SP - 283

EP - 290

JO - Trends in Plant Science

JF - Trends in Plant Science

IS - 5

ER -