TY - JOUR
T1 - Biosynthesis of glucosinolates - gene discovery and beyond
AU - Sønderby, Ida Elken
AU - Geu Flores, Fernando
AU - Halkier, Barbara Ann
PY - 2010/5
Y1 - 2010/5
N2 - Glucosinolates are sulfur-rich secondary metabolites characteristic of the Brassicales order with important biological and economic roles in plant defense and human nutrition. Application of systems biology tools continues to identify genes involved in the biosynthesis of glucosinolates. Recent progress includes genes in all three phases of the pathway, i.e. side-chain elongation of precursor amino acids, formation of the core glucosinolate structure and side-chain decoration. Major breakthroughs include the ability to produce glucosinolates in Nicotiana benthamiana, the finding that specific glucosinolates play a key role in Arabidopsis innate immune response, and a better understanding of the link between primary sulfur metabolism and glucosinolate biosynthesis.
AB - Glucosinolates are sulfur-rich secondary metabolites characteristic of the Brassicales order with important biological and economic roles in plant defense and human nutrition. Application of systems biology tools continues to identify genes involved in the biosynthesis of glucosinolates. Recent progress includes genes in all three phases of the pathway, i.e. side-chain elongation of precursor amino acids, formation of the core glucosinolate structure and side-chain decoration. Major breakthroughs include the ability to produce glucosinolates in Nicotiana benthamiana, the finding that specific glucosinolates play a key role in Arabidopsis innate immune response, and a better understanding of the link between primary sulfur metabolism and glucosinolate biosynthesis.
U2 - 10.1016/j.tplants.2010.02.005
DO - 10.1016/j.tplants.2010.02.005
M3 - Journal article
SN - 1360-1385
VL - 15
SP - 283
EP - 290
JO - Trends in Plant Science
JF - Trends in Plant Science
IS - 5
ER -