Betydning af sædcellens epigenetik for befrugtning og fosterudvikling

Translated title of the contribution: The importance of sperm epigenetics for conception and embryology

Marte Saupstad, Emil Andersen, Romain Barrès

    Abstract

    The epigenetic signature of spermatozoa is important for spermatogenesis, fertilisation and embryogenesis. New research indicates, that the epigenetic signature of spermatozoa can be altered following environmental changes, and that epigenetic patterns are heritable and can affect offspring health. Epigenetic markers of sperm correlate with the fertility status of men. These markers are not yet sufficiently integrated in the clinic to increase prediction of infertility, but there is a possibility, that the markers will play an important role in the future diagnosis of infertility.

    Translated title of the contributionThe importance of sperm epigenetics for conception and embryology
    Original languageDanish
    Article numberV02180152
    JournalUgeskrift for Laeger
    Volume180
    Pages (from-to)2-5
    ISSN0041-5782
    Publication statusPublished - 2018

    Fingerprint

    Dive into the research topics of 'The importance of sperm epigenetics for conception and embryology'. Together they form a unique fingerprint.

    Cite this