Betydning af sædcellens epigenetik for befrugtning og fosterudvikling

Marte Saupstad, Emil Andersen, Romain Barrès

    Abstract

    The epigenetic signature of spermatozoa is important for spermatogenesis, fertilisation and embryogenesis. New research indicates, that the epigenetic signature of spermatozoa can be altered following environmental changes, and that epigenetic patterns are heritable and can affect offspring health. Epigenetic markers of sperm correlate with the fertility status of men. These markers are not yet sufficiently integrated in the clinic to increase prediction of infertility, but there is a possibility, that the markers will play an important role in the future diagnosis of infertility.

    Bidragets oversatte titelThe importance of sperm epigenetics for conception and embryology
    OriginalsprogDansk
    ArtikelnummerV02180152
    TidsskriftUgeskrift for Laeger
    Vol/bind180
    Sider (fra-til)2-5
    ISSN0041-5782
    StatusUdgivet - 2018

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