Behandling af ideopatisk hypereosinofilt syndrom med imatinib

Anne Louise Sørensen; Herdis Larsen

Behandling af ideopatisk hypereosinofilt syndrom med imatinib

Translated title of the contribution: Treatment of idiopathic hypereosinophilic syndrome with imatinib

Anne Louise Sørensen, Herdis Larsen

Glycomics Program

Abstract

We here report a case of idiopathic hypereosinophilic syndrome with prompt response to treatment with imatinib. The patient presented with chest pain, myalgias, fatigue and weakness. Blood tests and bone marrow examination revealed striking eosinophilia. Clonal or reactive disorders were excluded by a wide range of diagnostic examinations. Treatment with high-dosis corticosteroids and hydroxyurea had little effect. Additional treatment with imatinib resulted in prompt symptomatic improvement and full haematological remission within five days of therapy.
Udgivelsesdato: 2008-Jan-21

Translated title of the contribution	Treatment of idiopathic hypereosinophilic syndrome with imatinib
Original language	Danish
Journal	Ugeskrift for læger
Volume	170
Issue number	4
Pages (from-to)	254
ISSN	0041-5782
Publication status	Published - 2008

Cite this

@article{107475802c1411df8ed1000ea68e967b,

title = "Behandling af ideopatisk hypereosinofilt syndrom med imatinib",

abstract = "We here report a case of idiopathic hypereosinophilic syndrome with prompt response to treatment with imatinib. The patient presented with chest pain, myalgias, fatigue and weakness. Blood tests and bone marrow examination revealed striking eosinophilia. Clonal or reactive disorders were excluded by a wide range of diagnostic examinations. Treatment with high-dosis corticosteroids and hydroxyurea had little effect. Additional treatment with imatinib resulted in prompt symptomatic improvement and full haematological remission within five days of therapy. Udgivelsesdato: 2008-Jan-21",

author = "S{\o}rensen, {Anne Louise} and Herdis Larsen",

note = "Keywords: Humans; Hypereosinophilic Syndrome; Male; Middle Aged; Piperazines; Protein Kinase Inhibitors; Pyrimidines",

year = "2008",

language = "Dansk",

volume = "170",

pages = "254",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "4",

}

TY - JOUR

T1 - Behandling af ideopatisk hypereosinofilt syndrom med imatinib

AU - Sørensen, Anne Louise

AU - Larsen, Herdis

N1 - Keywords: Humans; Hypereosinophilic Syndrome; Male; Middle Aged; Piperazines; Protein Kinase Inhibitors; Pyrimidines

PY - 2008

Y1 - 2008

N2 - We here report a case of idiopathic hypereosinophilic syndrome with prompt response to treatment with imatinib. The patient presented with chest pain, myalgias, fatigue and weakness. Blood tests and bone marrow examination revealed striking eosinophilia. Clonal or reactive disorders were excluded by a wide range of diagnostic examinations. Treatment with high-dosis corticosteroids and hydroxyurea had little effect. Additional treatment with imatinib resulted in prompt symptomatic improvement and full haematological remission within five days of therapy. Udgivelsesdato: 2008-Jan-21

AB - We here report a case of idiopathic hypereosinophilic syndrome with prompt response to treatment with imatinib. The patient presented with chest pain, myalgias, fatigue and weakness. Blood tests and bone marrow examination revealed striking eosinophilia. Clonal or reactive disorders were excluded by a wide range of diagnostic examinations. Treatment with high-dosis corticosteroids and hydroxyurea had little effect. Additional treatment with imatinib resulted in prompt symptomatic improvement and full haematological remission within five days of therapy. Udgivelsesdato: 2008-Jan-21

M3 - Tidsskriftartikel

C2 - 18282461

SN - 0041-5782

VL - 170

SP - 254

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 4

ER -