Behandling af ideopatisk hypereosinofilt syndrom med imatinib

Anne Louise Sørensen; Herdis Larsen

Behandling af ideopatisk hypereosinofilt syndrom med imatinib

Anne Louise Sørensen, Herdis Larsen

Glycomics Program

Abstract

We here report a case of idiopathic hypereosinophilic syndrome with prompt response to treatment with imatinib. The patient presented with chest pain, myalgias, fatigue and weakness. Blood tests and bone marrow examination revealed striking eosinophilia. Clonal or reactive disorders were excluded by a wide range of diagnostic examinations. Treatment with high-dosis corticosteroids and hydroxyurea had little effect. Additional treatment with imatinib resulted in prompt symptomatic improvement and full haematological remission within five days of therapy.
Udgivelsesdato: 2008-Jan-21

Bidragets oversatte titel	Treatment of idiopathic hypereosinophilic syndrome with imatinib
Originalsprog	Dansk
Tidsskrift	Ugeskrift for læger
Vol/bind	170
Udgave nummer	4
Sider (fra-til)	254
ISSN	0041-5782
Status	Udgivet - 2008

Citationsformater

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title = "Behandling af ideopatisk hypereosinofilt syndrom med imatinib",

abstract = "We here report a case of idiopathic hypereosinophilic syndrome with prompt response to treatment with imatinib. The patient presented with chest pain, myalgias, fatigue and weakness. Blood tests and bone marrow examination revealed striking eosinophilia. Clonal or reactive disorders were excluded by a wide range of diagnostic examinations. Treatment with high-dosis corticosteroids and hydroxyurea had little effect. Additional treatment with imatinib resulted in prompt symptomatic improvement and full haematological remission within five days of therapy. Udgivelsesdato: 2008-Jan-21",

author = "S{\o}rensen, {Anne Louise} and Herdis Larsen",

note = "Keywords: Humans; Hypereosinophilic Syndrome; Male; Middle Aged; Piperazines; Protein Kinase Inhibitors; Pyrimidines",

year = "2008",

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TY - JOUR

T1 - Behandling af ideopatisk hypereosinofilt syndrom med imatinib

AU - Sørensen, Anne Louise

AU - Larsen, Herdis

N1 - Keywords: Humans; Hypereosinophilic Syndrome; Male; Middle Aged; Piperazines; Protein Kinase Inhibitors; Pyrimidines

PY - 2008

Y1 - 2008

N2 - We here report a case of idiopathic hypereosinophilic syndrome with prompt response to treatment with imatinib. The patient presented with chest pain, myalgias, fatigue and weakness. Blood tests and bone marrow examination revealed striking eosinophilia. Clonal or reactive disorders were excluded by a wide range of diagnostic examinations. Treatment with high-dosis corticosteroids and hydroxyurea had little effect. Additional treatment with imatinib resulted in prompt symptomatic improvement and full haematological remission within five days of therapy. Udgivelsesdato: 2008-Jan-21

AB - We here report a case of idiopathic hypereosinophilic syndrome with prompt response to treatment with imatinib. The patient presented with chest pain, myalgias, fatigue and weakness. Blood tests and bone marrow examination revealed striking eosinophilia. Clonal or reactive disorders were excluded by a wide range of diagnostic examinations. Treatment with high-dosis corticosteroids and hydroxyurea had little effect. Additional treatment with imatinib resulted in prompt symptomatic improvement and full haematological remission within five days of therapy. Udgivelsesdato: 2008-Jan-21

M3 - Tidsskriftartikel

C2 - 18282461

SN - 0041-5782

VL - 170

SP - 254

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 4

ER -