Abstract
Heparan sulfate proteoglycan from the L2 rat yolk sac carcinoma has been purified and partially characterized. The proteoglycan has an apparent Mr of 750 000, 35% of which represents the core protein. The core protein seems to be homogeneous, whereas the heparan sulfate chains are heterogeneous with an Mr of about 50 000-70 000, with 30% of the glucosamine being N-sulfated. Antibodies raised against the core protein of the heparan sulfate proteoglycan reacted with basement membranes of various rat and human tissue.
| Original language | English |
|---|---|
| Journal | FEBS Letters |
| Volume | 173 |
| Issue number | 1 |
| Pages (from-to) | 75-9 |
| Number of pages | 4 |
| ISSN | 0014-5793 |
| Publication status | Published - 1984 |