Basement membrane heparan sulfate proteoglycan from the L2 rat yolk sac carcinoma.

TY - JOUR

T1 - Basement membrane heparan sulfate proteoglycan from the L2 rat yolk sac carcinoma.

AU - Fenger, M

AU - Wewer, U

AU - Albrechtsen, R

N1 - Keywords: Amino Acids; Animals; Basement Membrane; Dysgerminoma; Glycosaminoglycans; Heparan Sulfate Proteoglycans; Heparitin Sulfate; Hexosamines; Proteochondroitin Sulfates; Proteoglycans; Rats

PY - 1984

Y1 - 1984

N2 - Heparan sulfate proteoglycan from the L2 rat yolk sac carcinoma has been purified and partially characterized. The proteoglycan has an apparent Mr of 750 000, 35% of which represents the core protein. The core protein seems to be homogeneous, whereas the heparan sulfate chains are heterogeneous with an Mr of about 50 000-70 000, with 30% of the glucosamine being N-sulfated. Antibodies raised against the core protein of the heparan sulfate proteoglycan reacted with basement membranes of various rat and human tissue.

AB - Heparan sulfate proteoglycan from the L2 rat yolk sac carcinoma has been purified and partially characterized. The proteoglycan has an apparent Mr of 750 000, 35% of which represents the core protein. The core protein seems to be homogeneous, whereas the heparan sulfate chains are heterogeneous with an Mr of about 50 000-70 000, with 30% of the glucosamine being N-sulfated. Antibodies raised against the core protein of the heparan sulfate proteoglycan reacted with basement membranes of various rat and human tissue.

M3 - Journal article

C2 - 6235128

SN - 0014-5793

VL - 173

SP - 75

EP - 79

JO - F E B S Letters

JF - F E B S Letters

IS - 1

ER -