Application of interpretable artificial neural networks to early monoclonal antibodies development

Lorenzo Gentiluomo; Dierk Roessner; Dillen Augustijn; Hristo Svilenov; Alina Kulakova; Sujata Mahapatra; Gerhard Winter; Werner Streicher; Åsmund Rinnan; Günther H. J. Peters; Pernille Harris; Wolfgang Friess

doi:10.1016/j.ejpb.2019.05.017

Application of interpretable artificial neural networks to early monoclonal antibodies development

Lorenzo Gentiluomo, Dierk Roessner, Dillen Augustijn, Hristo Svilenov, Alina Kulakova, Sujata Mahapatra, Gerhard Winter, Werner Streicher, Åsmund Rinnan, Günther H. J. Peters, Pernille Harris, Wolfgang Friess

Food Analytics and Biotechnology

18 Citations (Scopus)

Original language	English
Journal	European Journal of Pharmaceutics and Biopharmaceutics
Volume	141
Pages (from-to)	81-89
ISSN	0939-6411
DOIs	https://doi.org/10.1016/j.ejpb.2019.05.017
Publication status	Published - Aug 2019

Keywords

Neural network(s)
Machine learning
Protein aggregation
Protein formulation
Monoclonal antibody
Stability

Access to Document

10.1016/j.ejpb.2019.05.017

Cite this

Gentiluomo, L., Roessner, D., Augustijn, D., Svilenov, H., Kulakova, A., Mahapatra, S., Winter, G., Streicher, W., Rinnan, Å., Peters, G. H. J., Harris, P., & Friess, W. (2019). Application of interpretable artificial neural networks to early monoclonal antibodies development. European Journal of Pharmaceutics and Biopharmaceutics, 141, 81-89. https://doi.org/10.1016/j.ejpb.2019.05.017

Gentiluomo, L, Roessner, D, Augustijn, D, Svilenov, H, Kulakova, A, Mahapatra, S, Winter, G, Streicher, W, Rinnan, Å, Peters, GHJ, Harris, P & Friess, W 2019, 'Application of interpretable artificial neural networks to early monoclonal antibodies development', European Journal of Pharmaceutics and Biopharmaceutics, vol. 141, pp. 81-89. https://doi.org/10.1016/j.ejpb.2019.05.017

@article{5cb4cef50a8442cabcbf6ac61c67a925,

title = "Application of interpretable artificial neural networks to early monoclonal antibodies development",

keywords = "Neural network(s), Machine learning, Protein aggregation, Protein formulation, Monoclonal antibody, Stability",

author = "Lorenzo Gentiluomo and Dierk Roessner and Dillen Augustijn and Hristo Svilenov and Alina Kulakova and Sujata Mahapatra and Gerhard Winter and Werner Streicher and {\AA}smund Rinnan and Peters, {G{\"u}nther H. J.} and Pernille Harris and Wolfgang Friess",

year = "2019",

month = aug,

doi = "10.1016/j.ejpb.2019.05.017",

language = "English",

volume = "141",

pages = "81--89",

journal = "European Journal of Pharmaceutics and Biopharmaceutics",

issn = "0939-6411",

publisher = "Elsevier",

}

TY - JOUR

T1 - Application of interpretable artificial neural networks to early monoclonal antibodies development

AU - Gentiluomo, Lorenzo

AU - Roessner, Dierk

AU - Augustijn, Dillen

AU - Svilenov, Hristo

AU - Kulakova, Alina

AU - Mahapatra, Sujata

AU - Winter, Gerhard

AU - Streicher, Werner

AU - Rinnan, Åsmund

AU - Peters, Günther H. J.

AU - Harris, Pernille

AU - Friess, Wolfgang

PY - 2019/8

Y1 - 2019/8

KW - Neural network(s)

KW - Machine learning

KW - Protein aggregation

KW - Protein formulation

KW - Monoclonal antibody

KW - Stability

U2 - 10.1016/j.ejpb.2019.05.017

DO - 10.1016/j.ejpb.2019.05.017

M3 - Journal article

C2 - 31112768

SN - 0939-6411

VL - 141

SP - 81

EP - 89

JO - European Journal of Pharmaceutics and Biopharmaceutics

JF - European Journal of Pharmaceutics and Biopharmaceutics

ER -

Application of interpretable artificial neural networks to early monoclonal antibodies development

Keywords

Access to Document

Fingerprint

Cite this