Analysis of biostructural changes, dynamics, and interactions - Small-angle X-ray scattering to the rescue

Bente Vestergaard

doi:10.1016/j.abb.2016.02.029

Analysis of biostructural changes, dynamics, and interactions - Small-angle X-ray scattering to the rescue

Bente Vestergaard

18 Citations (Scopus)

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Abstract

Solution small angle X-ray scattering from biological macromolecules (BioSAXS) plays an increasingly important role in biostructural research. The analysis of complex protein mixtures, dynamic equilibriums, intrinsic disorder and evolving structural processes is facilitated by SAXS data, either in stand-alone applications, or with SAXS taking a prominent role in hybrid biostructural analysis. This is not the least due to the significant advances in both hardware and software that have taken place in particular at the large-scale facilities. Here, recent developments and the future potential of BioSAXS are reviewed, exemplified by numerous examples of elegant applications to challenging systems.

Original language	English
Journal	Archives of Biochemistry and Biophysics
Volume	602
Pages (from-to)	69-79
Number of pages	11
ISSN	0003-9861
DOIs	https://doi.org/10.1016/j.abb.2016.02.029
Publication status	Published - 15 Jul 2016

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10.1016/j.abb.2016.02.029

1-s2.0-S0003986116300480-mainFinal published version, 1.59 MBLicence: CC BY

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Analysis of biostructural changes, dynamics, and interactions - Small-angle X-ray scattering to the rescue

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