Analysis of biostructural changes, dynamics, and interactions - Small-angle X-ray scattering to the rescue

Bente Vestergaard

doi:10.1016/j.abb.2016.02.029

Analysis of biostructural changes, dynamics, and interactions - Small-angle X-ray scattering to the rescue

Bente Vestergaard

18 Citationer (Scopus)

84 Downloads (Pure)

Abstract

Solution small angle X-ray scattering from biological macromolecules (BioSAXS) plays an increasingly important role in biostructural research. The analysis of complex protein mixtures, dynamic equilibriums, intrinsic disorder and evolving structural processes is facilitated by SAXS data, either in stand-alone applications, or with SAXS taking a prominent role in hybrid biostructural analysis. This is not the least due to the significant advances in both hardware and software that have taken place in particular at the large-scale facilities. Here, recent developments and the future potential of BioSAXS are reviewed, exemplified by numerous examples of elegant applications to challenging systems.

Originalsprog	Engelsk
Tidsskrift	Archives of Biochemistry and Biophysics
Vol/bind	602
Sider (fra-til)	69-79
Antal sider	11
ISSN	0003-9861
DOI	https://doi.org/10.1016/j.abb.2016.02.029
Status	Udgivet - 15 jul. 2016

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10.1016/j.abb.2016.02.029

1-s2.0-S0003986116300480-mainForlagets udgivne version, 1,59 MBLicens: CC BY

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Analysis of biostructural changes, dynamics, and interactions - Small-angle X-ray scattering to the rescue

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