An introduction to peptide nucleic acid

P E Nielsen; M Egholm

An introduction to peptide nucleic acid

Transcription, RNA, and Gene Medicine Program

226 Citations (Scopus)

Abstract

Peptide Nucleic Acid (PNA) is a powerful new biomolecular tool with a wide range of important applications. PNA mimics the behaviour of DNA and binds complementary nucleic acid strands. The unique chemical, physical and biological properties of PNA have been exploited to produce powerful biomolecular tools, antisense and antigene agents, molecular probes and biosensors.

Original language	English
Journal	Current Issues in Molecular Biology
Volume	1
Issue number	1-2
Pages (from-to)	89-104
Number of pages	16
ISSN	1467-3037
Publication status	Published - 1999

Keywords

DNA
DNA Probes
Molecular Structure
Nucleic Acid Conformation
Peptide Nucleic Acids
Temperature

Cite this

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AB - Peptide Nucleic Acid (PNA) is a powerful new biomolecular tool with a wide range of important applications. PNA mimics the behaviour of DNA and binds complementary nucleic acid strands. The unique chemical, physical and biological properties of PNA have been exploited to produce powerful biomolecular tools, antisense and antigene agents, molecular probes and biosensors.

KW - DNA

KW - DNA Probes

KW - Molecular Structure

KW - Nucleic Acid Conformation

KW - Peptide Nucleic Acids

KW - Temperature

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M3 - Review

C2 - 11475704

SN - 1467-3037

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EP - 104

JO - Current Issues in Molecular Biology

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An introduction to peptide nucleic acid

Abstract

Keywords

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