Abstract
The afferent endocrine factors that control eating can be separated into different categories. One obvious categorization is by the time course of their effects, with long-term factors that signal adiposity and short-term factors that operate within the time frame of single meals. The second obvious categorization is by the origin of the endocrine signalling molecules. The level of knowledge concerning the physiological mechanisms and relevance of the hormones that are implicated in the control of eating is clearly different. With the accumulating knowledge about the hormones' actions, various criteria have been developed for when the effect of a hormone can be considered 'physiologic'. This chapter treats the hormones separately and categorizes them by origin. It discusses ALL hormones that are implicated in eating control such as Gastrointestinal (GI) hormone and glucagon-like peptide-1, and focuses on particular examples. Finally, the chapter reviews some of the principal evidence supporting a role of leptin as an adiposity signal.
| Original language | English |
|---|---|
| Title of host publication | Neuroendocrinology of Appetite |
| Editors | Suzanne L. Dickson, Julian G. Mercer |
| Number of pages | 31 |
| Publisher | Wiley-Blackwell |
| Publication date | 22 Aug 2016 |
| Pages | 24-54 |
| Chapter | 2 |
| ISBN (Print) | 9781118839324 |
| ISBN (Electronic) | 9781118839317 |
| DOIs | |
| Publication status | Published - 22 Aug 2016 |
Keywords
- Afferent endocrine factors
- Gastrointestinal hormone
- Glucagon-like peptide-1
- Overeating control
- Peptide tyrosine tyrosine