A novel class of nucleolar RNAs from Tetrahymena

TY - JOUR

T1 - A novel class of nucleolar RNAs from Tetrahymena

AU - Nielsen, Henrik

AU - Orum, H

AU - Engberg, J

N1 - Keywords: Animals; Base Sequence; Cell Nucleolus; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Protozoan; RNA, Small Nuclear; Tetrahymena thermophila

PY - 1992

Y1 - 1992

N2 - We describe a family of at least four nucleolar RNAs (snoRNAs) from the ciliate, Tetrahymena. The snoRNAs are 120-140 nucleotides long, moderately AU-rich and contain no modified nucleotides. Their 5' ends are blocked by a cap of unknown nature. The snoRNAs can be folded into similar secondary structures consisting of two hairpins separated by a single-stranded AU-rich spacer. The sequences and secondary structures show no extensive sequence or secondary structure resemblance to any other small RNAs in the public databases.

AB - We describe a family of at least four nucleolar RNAs (snoRNAs) from the ciliate, Tetrahymena. The snoRNAs are 120-140 nucleotides long, moderately AU-rich and contain no modified nucleotides. Their 5' ends are blocked by a cap of unknown nature. The snoRNAs can be folded into similar secondary structures consisting of two hairpins separated by a single-stranded AU-rich spacer. The sequences and secondary structures show no extensive sequence or secondary structure resemblance to any other small RNAs in the public databases.

M3 - Journal article

C2 - 1644191

SN - 0014-5793

VL - 307

SP - 337

EP - 342

JO - F E B S Letters

JF - F E B S Letters

IS - 3

ER -