A DNA based five-state switch with programmed reversibility

Jonathan Burns; Søren Preus; Daniel Singleton; Eugen Stulz

doi:10.1039/c2cc35799b

A DNA based five-state switch with programmed reversibility

Jonathan Burns, Søren Preus, Daniel Singleton, Eugen Stulz

Department of Chemistry

11 Citations (Scopus)

Abstract

A programmable switch based on a DNA hairpin loop is functionalised with a rigid or flexible porphyrin or FAM and TAMRA FRET pair, which provides insight into the restructuring of the hairpin as well as porphyrin–porphyrin coupling. The switch contains five discrete states which can be accessed independently and followed by real-time spectroscopy, opening the way to a quinary computing code.

Original language	English
Journal	Chemical Communications
Volume	48
Issue number	90
Pages (from-to)	11088-11090
Number of pages	3
ISSN	1359-7345
DOIs	https://doi.org/10.1039/c2cc35799b
Publication status	Published - 17 Oct 2012

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abstract = "A programmable switch based on a DNA hairpin loop is functionalised with a rigid or flexible porphyrin or FAM and TAMRA FRET pair, which provides insight into the restructuring of the hairpin as well as porphyrin–porphyrin coupling. The switch contains five discrete states which can be accessed independently and followed by real-time spectroscopy, opening the way to a quinary computing code.",

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AU - Singleton, Daniel

AU - Stulz, Eugen

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DO - 10.1039/c2cc35799b

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JO - Chemical Communications

JF - Chemical Communications

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A DNA based five-state switch with programmed reversibility

Abstract

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