A DNA based five-state switch with programmed reversibility

Jonathan Burns; Søren Preus; Daniel Singleton; Eugen Stulz

doi:10.1039/c2cc35799b

A DNA based five-state switch with programmed reversibility

Jonathan Burns, Søren Preus, Daniel Singleton, Eugen Stulz

Kemisk Institut

11 Citationer (Scopus)

Abstract

A programmable switch based on a DNA hairpin loop is functionalised with a rigid or flexible porphyrin or FAM and TAMRA FRET pair, which provides insight into the restructuring of the hairpin as well as porphyrin–porphyrin coupling. The switch contains five discrete states which can be accessed independently and followed by real-time spectroscopy, opening the way to a quinary computing code.

Originalsprog	Engelsk
Tidsskrift	Chemical Communications
Vol/bind	48
Udgave nummer	90
Sider (fra-til)	11088-11090
Antal sider	3
ISSN	1359-7345
DOI	https://doi.org/10.1039/c2cc35799b
Status	Udgivet - 17 okt. 2012

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10.1039/c2cc35799b

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abstract = "A programmable switch based on a DNA hairpin loop is functionalised with a rigid or flexible porphyrin or FAM and TAMRA FRET pair, which provides insight into the restructuring of the hairpin as well as porphyrin–porphyrin coupling. The switch contains five discrete states which can be accessed independently and followed by real-time spectroscopy, opening the way to a quinary computing code.",

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AU - Burns, Jonathan

AU - Preus, Søren

AU - Singleton, Daniel

AU - Stulz, Eugen

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N2 - A programmable switch based on a DNA hairpin loop is functionalised with a rigid or flexible porphyrin or FAM and TAMRA FRET pair, which provides insight into the restructuring of the hairpin as well as porphyrin–porphyrin coupling. The switch contains five discrete states which can be accessed independently and followed by real-time spectroscopy, opening the way to a quinary computing code.

AB - A programmable switch based on a DNA hairpin loop is functionalised with a rigid or flexible porphyrin or FAM and TAMRA FRET pair, which provides insight into the restructuring of the hairpin as well as porphyrin–porphyrin coupling. The switch contains five discrete states which can be accessed independently and followed by real-time spectroscopy, opening the way to a quinary computing code.

U2 - 10.1039/c2cc35799b

DO - 10.1039/c2cc35799b

M3 - Journal article

SN - 1359-7345

VL - 48

SP - 11088

EP - 11090

JO - Chemical Communications

JF - Chemical Communications

IS - 90

ER -

A DNA based five-state switch with programmed reversibility

Abstract

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