No photo of Tuomas Oskari Kilpeläinen

Tuomas Oskari Kilpeläinen

PhD

 https://orcid.org/0000-0002-8349-3028
20072020

Research activity per year

Search results

  • 2012

    Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians

    Li, H., Oskari Kilpeläinen, T., Liu, C., Zhu, J., Liu, Y., Hu, C., Yang, Z., Zhang, W., Bao, W., Cha, S.-T., Wu, Y., Yang, T., Sekine, A., Choi, B. Y., Yajnik, C. S., Zhou, D., Takeuchi, F., Yamamoto, K., Chan, J. C. & Mani, K. R. & 45 others, Been, L. F., Imamura, M., Nakashima, E., Lee, N., Fujisawa, T., Karasawa, S., Wen, W., Joglekar, C. V., Lu, W., Chang, Y., Xiang, Y., Gao, Y., Liu, S., Song, Y., Kwak, S. H., Shin, H. D., Park, K., Fall, C. H. D., Kim, J. Y., Sham, P. C., Lam, K. S. L., Zheng, W., Shu, X., Deng, H., Ikegami, H., Krishnaveni, G. V., Sanghera, D. K., Chuang, L., Liu, L., Hu, R., Kim, Y., Daimon, M., Hotta, K., Jia, W., Kooner, J. S., Chambers, J. C., Chandak, G. R., Ma, R. C., Maeda, S., Dorajoo, R., Yokota, M., Takayanagi, R., Kato, N., Lin, X. & Loos, R. J. F., Apr 2012, In: Diabetologia. 55, 4, p. 981-95 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

    141 Citations (Scopus)

  • The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits

    Voight, B. F., Kang, H. M., Ding, J., Palmer, C. D., Sidore, C., Chines, P. S., Burtt, N. P., Fuchsberger, C., Li, Y., Erdmann, J., Frayling, T. M., Heid, I. M., Jackson, A. U., Johnson, T., Oskari Kilpeläinen, T., Lindgren, C. M., Morris, A. P., Prokopenko, I., Randall, J. C. & Saxena, R. & 29 others, Soranzo, N., Speliotes, E. K., Teslovich, T. M., Wheeler, E., Maguire, J., Parkin, M., Potter, S., Rayner, N. W., Robertson, N., Stirrups, K., Winckler, W., Sanna, S., Mulas, A., Nagaraja, R., Cucca, F., Barroso, I., Deloukas, P., Loos, R. J. F., Kathiresan, S., Munroe, P. B., Newton-Cheh, C., Pfeufer, A., Samani, N. J., Schunkert, H., Hirschhorn, J. N., Altshuler, D., McCarthy, M. I., Abecasis, G. R. & Boehnke, M., Aug 2012, In: P L o S Genetics (Online). 8, 8, p. e1002793

    Research output: Contribution to journal › Journal article › Research › peer-review

    372 Citations (Scopus)
  • 2011

    Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

    Oskari Kilpeläinen, T., Zillikens, M. C., Stančákova, A., Finucane, F. M., Ried, J. S., Langenberg, C., Zhang, W., Beckmann, J. S., Luan, J., Vandenput, L., Styrkarsdottir, U., Zhou, Y., Smith, A. V., Zhao, J.-H., Amin, N., Vedantam, S., Shin, S.-Y., Haritunians, T., Fu, M. & Feitosa, M. F. & 97 others, Kumari, M., Halldorsson, B. V., Tikkanen, E., Mangino, M., Hayward, C., Song, C., Arnold, A. M., Aulchenko, Y. S., Oostra, B. A., Campbell, H., Cupples, L. A., Davis, K. E., Döring, A., Eiriksdottir, G., Estrada, K., Fernández-Real, J. M., Garcia, M., Gieger, C., Glazer, N. L., Guiducci, C., Hofman, A., Humphries, S. E., Isomaa, B., Jacobs, L. C., Jula, A., Karasik, D., Karlsson, M. K., Khaw, K.-T., Kim, L. J., Kivimäki, M., Klopp, N., Kühnel, B., Kuusisto, J., Liu, Y., Ljunggren, O., Lorentzon, M., Luben, R. N., McKnight, B., Mellström, D., Mitchell, B. D., Mooser, V., Moreno, J. M., Männistö, S., O'Connell, J. R., Pascoe, L., Peltonen, L., Peral, B., Perola, M., Psaty, B. M., Salomaa, V., Savage, D. B., Semple, R. K., Skaric-Juric, T., Sigurdsson, G., Song, K. S., Spector, T. D., Syvänen, A.-C., Talmud, P. J., Thorleifsson, G., Thorsteinsdottir, U., Uitterlinden, A. G., van Duijn, C. M., Vidal-Puig, A., Wild, S. H., Wright, A. F., Clegg, D. J., Schadt, E., Wilson, J., Rudan, I., Ripatti, S., Borecki, I. B., Shuldiner, A. R., Ingelsson, E., Jansson, J.-O., Kaplan, R. C., Gudnason, V., Harris, T. B., Groop, L., Kiel, D. P., Rivadeneira, F., Walker, M., Barroso, I., Vollenweider, P., Waeber, G., Chambers, J. C., Kooner, J. S., Soranzo, N., Hirschhorn, J. N., Stefansson, K., Wichmann, H.-E., Ohlsson, C., O'Rahilly, S., Wareham, N. J., Speliotes, E. K., Fox, C. S., Laakso, M. & Loos, R. J. F., Aug 2011, In: Nature Genetics. 43, 8, p. 753-60 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

    215 Citations (Scopus)

  • Genome-wide association studies and human population obesity

    Kilpeläinen, T. O. & Loos, R. J., 2011, Obesity before Birth: Maternal and prenatal influences on the offspring. Lustig, R. H. (ed.). New York, USA: Springer, p. 95-112 (Endocrine Updates, Vol. 30).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  • Obesity-susceptibility loci have a limited influence on birth weight: a meta-analysis of up to 28,219 individuals

    Oskari Kilpeläinen, T., den Hoed, M., Ong, K. K., Grøntved, A., Brage, S., Jameson, K., Cooper, C., Khaw, K.-T., Ekelund, U., Wareham, N. J., Loos, R. J. F. & Early Growth Genetics Consortium, 1 Apr 2011, In: American Journal of Clinical Nutrition. 93, 4, p. 851-60 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

    48 Citations (Scopus)

  • Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children

    Oskari Kilpeläinen, T., Qi, L., Brage, S., Sharp, S. J., Sonestedt, E., Demerath, E., Ahmad, T., Mora, S., Kaakinen, M., Sandholt, C. H., Holzapfel, C., Autenrieth, C. S., Hyppönen, E., Cauchi, S., He, M., Kutalik, Z., Kumari, M., Stancáková, A., Meidtner, K. & Balkau, B. & 96 others, Tan, J. T., Mangino, M., Timpson, N. J., Song, Y., Zillikens, M. C., Jablonski, K. A., Garcia, M. E., Johansson, S., Bragg-Gresham, J. L., Wu, Y., van Vliet-Ostaptchouk, J. V., Onland-Moret, N. C., Zimmermann, E., Rivera, N. V., Tanaka, T., Stringham, H. M., Silbernagel, G., Kanoni, S., Feitosa, M. F., Snitker, S., Ruiz, J. R., Metter, J., Larrad, M. T. M., Atalay, M., Hakanen, M., Amin, N., Cavalcanti-Proença, C., Grøntved, A., Hallmans, G., Jansson, J.-O., Kuusisto, J., Kähönen, M., Lutsey, P. L., Nolan, J. J., Palla, L., Pedersen, O., Pérusse, L., Renström, F., Scott, R. A., Shungin, D., Sovio, U., Tammelin, T. H., Rönnemaa, T., Lakka, T. A., Uusitupa, M., Rios, M. S., Ferrucci, L., Bouchard, C., Meirhaeghe, A., Fu, M., Walker, M., Borecki, I. B., Dedoussis, G. V., Fritsche, A., Ohlsson, C., Boehnke, M., Bandinelli, S., van Duijn, C. M., Ebrahim, S., Lawlor, D. A., Gudnason, V., Harris, T. B., Sørensen, T. I. A., Mohlke, K. L., Hofman, A., Uitterlinden, A. G., Tuomilehto, J., Lehtimäki, T., Raitakari, O., Isomaa, B., Njølstad, P. R., Florez, J. C., Liu, S., Ness, A., Spector, T. D., Tai, E. S., Froguel, P., Boeing, H., Laakso, M., Marmot, M., Bergmann, S., Power, C., Khaw, K.-T., Chasman, D., Ridker, P., Hansen, T., Monda, K. L., Illig, T., Järvelin, M.-R., Wareham, N. J., Hu, F. B., Groop, L. C., Orho-Melander, M., Ekelund, U., Franks, P. W. & Loos, R. J. F., 1 Nov 2011, In: P L o S Medicine (Online). 8, 11, p. e1001116

    Research output: Contribution to journal › Journal article › Research › peer-review

    354 Citations (Scopus)
  • 2010

    Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    Speliotes, E. K., Willer, C. J., Berndt, S. I., Monda, K. L., Thorleifsson, G., Jackson, A. U., Allen, H. L., Lindgren, C. M., Luan, J., Mägi, R., Randall, J. C., Vedantam, S., Winkler, T. W., Lu, Q., Workalemahu, T., Heid, I. M., Steinthorsdottir, V., Stringham, H. M., Weedon, M. N. & Wheeler, E. & 31 others, Wood, A. R., Ferreira, T., Weyant, R. J., Segrè, A. V., Estrada, K., Liang, L., Nemesh, J., Park, J.-H., Gustafsson, S., Oskari Kilpeläinen, T., Yang, J., Bouatia-Naji, N., Esko, T., Feitosa, M. F., Kutalik, Z., Mangino, M., Raychaudhuri, S., Scherag, A., Smith, A. V., Welch, R., Zhao, J. H., Aben, K. K., Absher, D. M., Amin, N., Dixon, A. L., Gjesing, A. P., Jørgensen, T., Witte, D. R., Hansen, T., Pedersen, O. & MAGIC, 1 Nov 2010, In: Nature Genetics. 42, 11, p. 937-48 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

    2060 Citations (Scopus)

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    Lango Allen, H., Estrada, K., Lettre, G., Berndt, S. I., Weedon, M. N., Rivadeneira, F., Willer, C. J., Jackson, A. U., Vedantam, S., Raychaudhuri, S., Ferreira, T., Wood, A. R., Weyant, R. J., Segrè, A. V., Speliotes, E. K., Wheeler, E., Soranzo, N., Park, J.-H., Yang, J. & Gudbjartsson, D. & 273 others, Heard-Costa, N. L., Randall, J. C., Qi, L., Vernon Smith, A., Mägi, R., Pastinen, T., Liang, L., Heid, I. M., Luan, J., Thorleifsson, G., Winkler, T. W., Goddard, M. E., Sin Lo, K., Palmer, C., Workalemahu, T., Aulchenko, Y. S., Johansson, A., Zillikens, M. C., Feitosa, M. F., Esko, T., Johnson, T., Ketkar, S., Kraft, P., Mangino, M., Prokopenko, I., Absher, D., Albrecht, E., Ernst, F., Glazer, N. L., Hayward, C., Hottenga, J.-J., Jacobs, K. B., Knowles, J. W., Kutalik, Z., Monda, K. L., Polasek, O., Preuss, M., Rayner, N. W., Robertson, N. R., Steinthorsdottir, V., Tyrer, J. P., Voight, B. F., Wiklund, F., Xu, J., Zhao, J. H., Nyholt, D. R., Pellikka, N., Perola, M., Perry, J. R. B., Surakka, I., Tammesoo, M.-L., Altmaier, E. L., Amin, N., Aspelund, T., Bhangale, T., Boucher, G., Chasman, D. I., Chen, C., Coin, L., Cooper, M. N., Dixon, A. L., Gibson, Q., Grundberg, E., Hao, K., Juhani Junttila, M., Kaplan, L. M., Kettunen, J., König, I. R., Kwan, T., Lawrence, R. W., Levinson, D. F., Lorentzon, M., McKnight, B., Morris, A. P., Müller, M., Suh Ngwa, J., Purcell, S., Rafelt, S., Salem, R. M., Salvi, E., Sanna, S., Shi, J., Sovio, U., Thompson, J. R., Turchin, M. C., Vandenput, L., Verlaan, D. J., Vitart, V., White, C. C., Ziegler, A., Almgren, P., Balmforth, A. J., Campbell, H., Citterio, L., De Grandi, A., Dominiczak, A., Duan, J., Elliott, P., Elosua, R., Eriksson, J. G., Freimer, N. B., Geus, E. J. C., Glorioso, N., Haiqing, S., Hartikainen, A.-L., Havulinna, A. S., Hicks, A. A., Hui, J., Igl, W., Illig, T., Jula, A., Kajantie, E., Oskari Kilpeläinen, T., Koiranen, M., Kolcic, I., Koskinen, S., Kovacs, P., Laitinen, J., Liu, J., Lokki, M.-L., Marusic, A., Maschio, A., Meitinger, T., Mulas, A., Paré, G., Parker, A. N., Peden, J. F., Petersmann, A., Pichler, I., Pietiläinen, K. H., Pouta, A., Ridderstråle, M., Rotter, J. I., Sambrook, J. G., Sanders, A. R., Schmidt, C. O., Sinisalo, J., Smit, J. H., Stringham, H. M., Bragi Walters, G., Widen, E., Wild, S. H., Willemsen, G., Zagato, L., Zgaga, L., Zitting, P., Alavere, H., Farrall, M., McArdle, W. L., Nelis, M., Peters, M. J., Ripatti, S., van Meurs, J. B. J., Aben, K. K., Ardlie, K. G., Beckmann, J. S., Beilby, J. P., Bergman, R. N., Bergmann, S., Collins, F. S., Cusi, D., den Heijer, M., Eiriksdottir, G., Gejman, P. V., Hall, A. S., Hamsten, A., Huikuri, H. V., Iribarren, C., Kähönen, M., Kaprio, J., Kathiresan, S., Kiemeney, L., Kocher, T., Launer, L. J., Lehtimäki, T., Melander, O., Mosley, T. H., Musk, A. W., Nieminen, M. S., O'Donnell, C. J., Ohlsson, C., Oostra, B., Palmer, L. J., Raitakari, O., Ridker, P. M., Rioux, J. D., Rissanen, A., Rivolta, C., Schunkert, H., Shuldiner, A. R., Siscovick, D. S., Stumvoll, M., Tönjes, A., Tuomilehto, J., van Ommen, G.-J., Viikari, J., Heath, A. C., Martin, N. G., Montgomery, G. W., Province, M. A., Kayser, M., Arnold, A. M., Atwood, L. D., Boerwinkle, E., Chanock, S. J., Deloukas, P., Gieger, C., Grönberg, H., Hall, P., Hattersley, A. T., Hengstenberg, C., Hoffman, W., Lathrop, G. M., Salomaa, V., Schreiber, S., Uda, M., Waterworth, D., Wright, A. F., Assimes, T. L., Barroso, I., Hofman, A., Mohlke, K. L., Boomsma, D. I., Caulfield, M. J., Cupples, L. A., Erdmann, J., Fox, C. S., Gudnason, V., Gyllensten, U., Harris, T. B., Hayes, R. B., Jarvelin, M.-R., Mooser, V., Munroe, P. B., Ouwehand, W. H., Penninx, B. W., Pramstaller, P. P., Quertermous, T., Rudan, I., Samani, N. J., Spector, T. D., Völzke, H., Watkins, H., Wilson, J., Groop, L. C., Haritunians, T., Hu, F. B., Kaplan, R. C., Metspalu, A., North, K. E., Schlessinger, D., Wareham, N. J., Hunter, D. J., O'Connell, J. R., Strachan, D. P., Wichmann, H.-E., Borecki, I. B., van Duijn, C. M., Schadt, E. E., Thorsteinsdottir, U., Peltonen, L., Uitterlinden, A. G., Visscher, P. M., Chatterjee, N., Loos, R. J. F., Boehnke, M., McCarthy, M. I., Ingelsson, E., Lindgren, C. M., Abecasis, G. R., Stefansson, K., Frayling, T. M. & Hirschhorn, J. N., 14 Oct 2010, In: Nature. 467, 7317, p. 832-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

    1376 Citations (Scopus)

  • Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

    Heid, I. M., Jackson, A. U., Randall, J. C., Winkler, T. W., Qi, L., Steinthorsdottir, V., Thorleifsson, G., Zillikens, M. C., Speliotes, E. K., Mägi, R., Workalemahu, T., White, C. C., Bouatia-Naji, N., Harris, T. B., Berndt, S. I., Ingelsson, E., Willer, C. J., Weedon, M. N., Luan, J. & Vedantam, S. & 31 others, Esko, T., Oskari Kilpeläinen, T., Kutalik, Z., Li, S., Monda, K. L., Dixon, A. L., Holmes, C. C., Kaplan, L. M., Liang, L., Min, J. L., Moffatt, M. F., Molony, C., Nicholson, G., Schadt, E. E., Zondervan, K. T., Feitosa, M. F., Ferreira, T., Allen, H. L., Weyant, R. J., Wheeler, E., Wood, A. R., Estrada, K., Goddard, M. E., Lettre, G., Mangino, M., Gjesing, A. P., Witte, D. R., Hansen, T., Jørgensen, T., Pedersen, O. & MAGIC, 1 Nov 2010, In: Nature Genetics. 42, 11, p. 949-60 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

    660 Citations (Scopus)

  • The rs1800629 polymorphism in the TNF gene interacts with physical activity on the changes in C-reactive protein levels in the Finnish Diabetes Prevention Study

    Oskari Kilpeläinen, T., Laaksonen, D. E., Lakka, T. A., Herder, C., Koenig, W., Lindström, J., Eriksson, J. G., Uusitupa, M., Kolb, H., Laakso, M., Tuomilehto, J. & Finnish Diabetes Prevention Study, Nov 2010, In: Experimental and Clinical Endocrinology and Diabetes. 118, 10, p. 757-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

    12 Citations (Scopus)

  • Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

    Elks, C. E., Perry, J. R. B., Sulem, P., Chasman, D. I., Franceschini, N., He, C., Lunetta, K. L., Visser, J. A., Byrne, E. M., Cousminer, D. L., Gudbjartsson, D. F., Esko, T., Feenstra, B., Hottenga, J.-J., Koller, D. L., Kutalik, Z., Lin, P., Mangino, M., Marongiu, M. & McArdle, P. F. & 31 others, Smith, A. V., Stolk, L., van Wingerden, S. H., Zhao, J. H., Albrecht, E., Corre, T., Ingelsson, E., Hayward, C., Magnusson, P. K. E., Smith, E. N., Ulivi, S., Warrington, N. M., Zgaga, L., Alavere, H., Amin, N., Aspelund, T., Bandinelli, S., Barroso, I., Berenson, G. S., Bergmann, S., Blackburn, H., Boerwinkle, E., Buring, J. E., Busonero, F., Campbell, H., Chanock, S. J., Chen, W., Cornelis, M. C., Couper, D., Oskari Kilpeläinen, T. & GIANT Consortium, 1 Dec 2010, In: Nature Genetics. 42, 12, p. 1077-85 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

    356 Citations (Scopus)
  • 2009

    Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study

    Oskari Kilpeläinen, T., Bingham, S. A., Khaw, K.-T., Wareham, N. J. & Loos, R. J. F., 15 Sept 2009, In: Human Molecular Genetics. 18, 18, p. 3496-501 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

    53 Citations (Scopus)
  • 2008

    Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome: The Finnish Diabetes Prevention Study

    Oskari Kilpeläinen, T., Lakka, T. A., Laaksonen, D. E., Mager, U., Salopuro, T., Kubaszek, A., Todorova, B., Laukkanen, O., Lindström, J., Eriksson, J. G., Hämäläinen, H., Aunola, S., Ilanne-Parikka, P., Keinänen-Kiukaanniemi, S., Tuomilehto, J., Laakso, M., Uusitupa, M. & Finnish Diabetes Prevention Study Group, Mar 2008, In: Metabolism. 57, 3, p. 428-36 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

    34 Citations (Scopus)

  • SNPs in PPARG associate with type 2 diabetes and interact with physical activity

    Oskari Kilpeläinen, T., Lakka, T. A., Laaksonen, D. E., Lindström, J., Eriksson, J. G., Valle, T. T., Hämäläinen, H., Ilanne-Parikka, P., Keinänen-Kiukaanniemi, S., Lindi, V., Tuomilehto, J., Uusitupa, M. & Laakso, M., Jan 2008, In: Medicine and Science in Sports and Exercise. 40, 1, p. 25-33 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

    34 Citations (Scopus)
  • 2007

    Epidemiological studies of exercise in diabetes prevention

    Hu, G., Lakka, T. A., Oskari Kilpeläinen, T. & Tuomilehto, J., Jun 2007, In: Applied Physiology, Nutrition and Metabolism. 32, 3, p. 583-95 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

    50 Citations (Scopus)

  • Physical activity modifies the effect of SNPs in the SLC2A2 (GLUT2) and ABCC8 (SUR1) genes on the risk of developing type 2 diabetes

    Oskari Kilpeläinen, T., Lakka, T. A., Laaksonen, D. E., Laukkanen, O., Lindström, J., Eriksson, J. G., Valle, T. T., Hämäläinen, H., Aunola, S., Ilanne-Parikka, P., Keinänen-Kiukaanniemi, S., Tuomilehto, J., Uusitupa, M., Laakso, M. & Finnish Diabetes Prevention Study Group, 22 Oct 2007, In: Physiological Genomics. 31, 2, p. 264-72 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

    33 Citations (Scopus)