Research output per year
Research output per year
Search results
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2019
Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants
Jensen, S. B., Fahnøe, U., Pham, L. V., Serre, S. B. N., Tang, Q., Ghanem, L., Pedersen, M. S., Ramirez, S., Humes, D., Pihl, A. F., Filskov, J., Sølund, C. S., Dietz, J., Fourati, S., Pawlotsky, J. M., Sarrazin, C., Weis, N., Schønning, K., Krarup, H., Bukh, J., & 1 others, Sept 2019, In: Hepatology. 70, 3, p. 771-787 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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HCV genotype 1-6 NS3 residue 80 substitutions impact protease inhibitor activity and promote viral escape
Pham, L. V., Jensen, S. B., Fahnøe, U., Pedersen, M. S., Tang, Q., Ghanem, L., Ramirez, S., Humes, D., Serre, S. B. N., Schønning, K., Bukh, J. & Gottwein, J. M., Mar 2019, In: Journal of Hepatology. 70, 3, p. 388-397Research output: Contribution to journal › Journal article › Research › peer-review
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2018
Current status and future development of infectious cell-culture models for the major genotypes of hepatitis C virus: Essential tools in testing of antivirals and emerging vaccine strategies
Ramirez, S. & Bukh, J., 2018, In: Antiviral Research. 158, p. 264-287 24 p.Research output: Contribution to journal › Review › peer-review
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Efficacy of NS5A Inhibitors Against Hepatitis C Virus Genotypes 1–7 and Escape Variants
Gottwein, J. M., Pham, L. V., Mikkelsen, L. S., Ghanem, L., Ramirez, S., Scheel, T. K. H., Carlsen, T. H. R. & Bukh, J., Apr 2018, In: Gastroenterology. 154, 5, p. 1435-1448 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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HCV Genotype 6a Escape from and Resistance to Velpatasvir, Pibrentasvir, and Sofosbuvir in Robust Infectious Cell Culture Models
Pham, L., Ramirez Almeida, S., Gottwein, J. M., Fahnøe, U., Li, Y., Pedersen, J. & Bukh, J., Jun 2018, In: Gastroenterology. 154, 8, p. 2194-2208.e12Research output: Contribution to journal › Journal article › Research › peer-review
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Recombinant hepatitis C virus genotype 5a infectious cell culture systems expressing minimal JFH1 NS5B sequences permit polymerase inhibitor studies
Humes, D., Ramirez, S., Jensen, T. B., Li, Y. P., Gottwein, J. M. & Bukh, J., 2018, In: Virology. 522, p. 177-192 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ribavirin-induced mutagenesis across the complete open reading frame of hepatitis C virus genotypes 1a and 3a
Mejer, N., Fahnøe, U., Galli, A., Ramirez, S., Benfield, T. & Bukh, J., 2018, In: Journal of General Virology. 99, 8, p. 1066-1077 12 p., 001095.Research output: Contribution to journal › Journal article › Research › peer-review
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2017
Efficient hepatitis c virus genotype 1b core-NS5A recombinants permit efficacy testing of protease and NS5A inhibitors
Pham, L. V., Ramirez Almeida, S., Carlsen, T. H. R., Li, Y-P., Gottwein, J. M. & Bukh, J., 2017, In: Antimicrobial Agents and Chemotherapy. 61, 6, 19 p., e00037-17.Research output: Contribution to journal › Journal article › Research › peer-review
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2016
Robust HCV Genotype 3a Infectious Cell Culture System Permits Identification of Escape Variants With Resistance to Sofosbuvir
Ramirez Almeida, S., Mikkelsen, L. S., Gottwein, J. M. & Bukh, J., Nov 2016, In: Gastroenterology. 151, 5, p. 973-985.e2Research output: Contribution to journal › Journal article › Research › peer-review
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2015
Efficient infectious cell culture systems of the hepatitis C virus (HCV) prototype strains HCV-1 and H77
Li, Y-P., Ramirez, S., Mikkelsen, L. & Bukh, J., Jan 2015, In: Journal of Virology. 89, 1, p. 811-23 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Substitutions at NS3 Residue 155, 156, or 168 of Hepatitis C Virus Genotypes 2 to 6 Induce Complex Patterns of Protease Inhibitor Resistance
Jensen, S. B., Serre, S. B. N., Humes, D. G., Ramirez Almeida, S., Li, Y-P., Bukh, J. & Gottwein, J. M., 1 Dec 2015, In: Antimicrobial Agents and Chemotherapy. 59, 12, p. 7426-7436 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2014
Nationwide experience of treatment with protease inhibitors in chronic hepatitis C patients in denmark: identification of viral resistance mutations
Sølund, C., Krarup, H., Ramirez, S., Thielsen, P., Røge, B. T., Lunding, S., Barfod, T. S., Madsen, L. G., Tarp, B., Christensen, P. B., Gerstoft, J., Laursen, A. L., Bukh, J., Weis, N. & DANHEP Group, 1 Dec 2014, In: PLOS ONE. 9, 12, p. 1-20 20 p., e113034.Research output: Contribution to journal › Journal article › Research › peer-review