Research output per year
Research output per year
Personal profile
Short presentation
My PhD project entitled “Transepithelial Drug Delivery Mechanisms by Peptide Carriers” involves investigation of physio-chemical properties of carrier peptides and the effect hereof on enhancing intestinal insulin delivery. In this context, intermolecular interactions between the carrier peptides and insulin or the cell membrane will be investigated. This work will shed light on the mechanisms of permeation and hereby aid the design of drug delivery systems with tailored physio-chemical properties for therapeutic peptides and proteins.
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Collaborations and top research areas from the last five years
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Research output
- 1 Journal article
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Evaluation of drug permeation under fed state conditions using mucus-covered Caco-2 cell epithelium
Birch, D., Diedrichsen, R. G., Christophersen, P. C., Mu, H. & Nielsen, H. M., 15 Jun 2018, In: European Journal of Pharmaceutical Sciences. 118, p. 144-153Research output: Contribution to journal › Journal article › Research › peer-review
Datasets
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Interaction of peptide-loaded photocatalytic nanoparticles with bacterial membrane components - lipopolysaccharides
Caselli, L. (Creator), Diedrichsen, R. G. (Creator), Martin, M. (Creator), Samantha, M. (Creator), Thomas, S. (Creator), Federica, S. (Creator) & Tanja, T. (Creator), Institut Laue-Langevin (ILL), 2023
DOI: 10.5291/ill-data.9-13-1047, https://doi.ill.fr/10.5291/ILL-DATA.9-13-1047
Dataset
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Investigating structural organization of cell-penetrating peptides and insulin complexes
Morck, N. H. (Creator), Browning, K. (Creator), Hussein, C. (Creator), Diedrichsen, R. G. (Creator), Klodzinska, S. N. (Creator) & Sylvain, P. (Creator), Institut Laue-Langevin (ILL), 2020
DOI: 10.5291/ill-data.9-13-858, https://doi.ill.fr/10.5291/ILL-DATA.9-13-858
Dataset