Ole Mathiesen

Research output

Research output per year 2008 2017 2019

• 30 Journal article
• 6 Review
• 2 Editorial

Research output per year

Research output per year

Search results

• 2019

  Agents intervening against delirium in the intensive care unit (AID-ICU) - Protocol for a randomised placebo-controlled trial of haloperidol in patients with delirium in the ICU

  Andersen-Ranberg, N. C., Poulsen, L. M., Perner, A., Wetterslev, J., Estrup, S., Lange, T., Ebdrup, B. H., Hästbacka, J., Morgan, M. P. G., Citerio, G., Zafrani, L., Caballero, J., Oxenbøll-Collet, M., Weber, S-O., Andreasen, A. S., Bestle, M., Pedersen, H. B. S., Hildebrandt, T., Thee, C., Jensen, T. B., & 3 othersDey, N., Nielsen, L. G. & Mathiesen, O., 1 Nov 2019, In: Acta Anaesthesiologica Scandinavica. 63, 10, p. 1426-1433 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Delirium 100%
  • Haloperidol 95%
  • Intensive Care Units 72%
  • Placebos 60%
  • Randomized Controlled Trials 58%
  3 Citations (Scopus)

• Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours after Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial

  Thybo, K. H., Hägi-Pedersen, D., Dahl, J. B., Wetterslev, J., Nersesjan, M., Jakobsen, J. C., Pedersen, N. A., Overgaard, S., Schrøder, H. M., Schmidt, H., Bjørck, J. G., Skovmand, K., Frederiksen, R., Buus-Nielsen, M., Sørensen, C. V., Kruuse, L. S., Lindholm, P. & Mathiesen, O., 2019, In: JAMA - Journal of the American Medical Association. 321, 6, p. 562-571 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • 4-(5-thioxo-5H-1,2-dithiol-3-yl)-phenyl 2-(4-isobutyphenyl)propanoate 100%
  • Ibuprofen 63%
  • Acetaminophen 57%
  • Arthroplasty 51%
  • Morphine 50%
  36 Citations (Scopus)

• Pain management after total hip arthroplasty at five different Danish hospitals: A prospective, observational cohort study of 501 patients

  Geisler, A., Dahl, J. B., Thybo, K. H., Pedersen, T. H., Jørgensen, M. L., Hansen, D., Schulze, L. K., Persson, E. I. & Mathiesen, O., Aug 2019, In: Acta Anaesthesiologica Scandinavica. 63, 7, p. 923-930 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Pain Management 100%
  • Arthroplasty 94%
  • Hip 81%
  • Observational Studies 77%
  • Cohort Studies 67%
  4 Citations (Scopus)

• Systemic dexmedetomidine is not as efficient as perineural dexmedetomidine in prolonging an ulnar nerve block

  Andersen, J. H., Jaeger, P., Grevstad, U., Estrup, S., Geisler, A., Vilhelmsen, F., Dahl, J. B., Laier, G. H., Ilfeld, B. M. & Mathiesen, O., 1 Mar 2019, In: Regional Anesthesia and Pain Medicine. 44, 3, p. 333-340

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Dexmedetomidine 100%
  • Ulnar Nerve 95%
  • Nerve Block 90%
  • Ropivacaine 64%
  • Joints 6%
  9 Citations (Scopus)
• 2018

  Cognitive Function 3 and 12 Months After ICU Discharge: A Prospective Cohort Study

  Estrup, S., Kjer, C. K. W., Vilhelmsen, F., Poulsen, L. M., Gøgenur, I. & Mathiesen, O., 1 Dec 2018, In: Critical Care Medicine. 46, 12, p. e1121-e1127

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cognition 100%
  • Cohort Studies 86%
  • Prospective Studies 80%
  • Neuropsychological Tests 49%
  • APACHE 13%

• Delirium and effect of circadian light in the intensive care unit: a retrospective cohort study

  Estrup, S., Kjer, C. K. W., Poulsen, L. M., Gøgenur, I. & Mathiesen, O., Mar 2018, In: Acta Anaesthesiologica Scandinavica. 62, 3, p. 367-375

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Delirium 100%
  • Intensive Care Units 72%
  • Light 61%
  • Cohort Studies 59%
  • Retrospective Studies 58%
  9 Citations (Scopus)

• Evolution of bias and sample size in postoperative pain management trials after hip and knee arthroplasty

  Karlsen, A. P. H., Dahl, J. B. & Mathiesen, O., May 2018, In: Acta Anaesthesiologica Scandinavica. 62, 5, p. 666-676 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Knee Replacement Arthroplasties 100%
  • Postoperative Pain 99%
  • Pain Management 99%
  • Sample Size 87%
  • Hip 81%
  5 Citations (Scopus)

• Haloperidol for delirium in critically ill patients - protocol for a systematic review

  Barbateskovic, M., Kraus, S. R., Collet, M. O., Mathiesen, O., Jakobsen, J. C., Perner, A. & Wetterslev, J., May 2018, In: Acta Anaesthesiologica Scandinavica. 62, 5, p. 712-723 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Delirium 100%
  • Haloperidol 95%
  • Critical Illness 81%
  • Systematic Reviews 64%
  • Randomized Controlled Trials 35%
  3 Citations (Scopus)

• Heterogenic control groups in randomized, controlled, analgesic trials of total hip and knee arthroplasty

  Karlsen, A. P., Mathiesen, O. & Dahl, J. B., Mar 2018, In: Minerva Anestesiologica. 84, 3, p. 346-362 17 p.

  Research output: Contribution to journal › Review › peer-review

  • Knee Replacement Arthroplasties 100%
  • Opioid Analgesics 87%
  • Analgesics 84%
  • Hip 81%
  • Randomized Controlled Trials 66%
  4 Citations (Scopus)

• Sensory distribution of the lateral femoral cutaneous nerve block - a randomised, blinded trial

  Nersesjan, M., Hägi-Pedersen, D., Andersen, J. H., Mathiesen, O., Dahl, J. B., Broeng, L. & Thybo, K. H., Jul 2018, In: Acta Anaesthesiologica Scandinavica. 62, 6, p. 863-873 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Femoral Nerve 100%
  • Nerve Block 86%
  • Skin 41%
  • Ropivacaine 32%
  • Temperature 17%
  6 Citations (Scopus)
• 2017

  An urgent call for improved quality of trial design and reporting in postoperative pain research

  Fabritius, M. L., Wetterslev, J., Dahl, J. B. & Mathiesen, O., 1 Jan 2017, In: Acta Anaesthesiologica Scandinavica. 61, 1, p. 8-10 3 p.

  Research output: Contribution to journal › Editorial

  3 Citations (Scopus)

• Benefit and harm of pregabalin in acute pain treatment: a systematic review with meta-analyses and trial sequential analyses

  Fabritius, M. L., Strøm, C., Koyuncu, S., Jæger, P., Petersen, P. L., Geisler, A., Wetterslev, J., Dahl, J. B. & Mathiesen, O., 1 Oct 2017, In: British Journal of Anaesthesia. 119, 4, p. 775-791

  Research output: Contribution to journal › Review › peer-review

  • Pregabalin 100%
  • Acute Pain 78%
  • Meta-Analysis 54%
  • Systematic Reviews 54%
  • Postoperative Pain 24%
  38 Citations (Scopus)

• Clonidine used as a perineural adjuvant to ropivacaine, does not prolong the duration of sensory block when controlling for systemic effects: A paired, blinded, randomized trial in healthy volunteers

  Andersen, J. H., Jaeger, P., Sonne, T. L., Dahl, J. B., Mathiesen, O. & Grevstad, U., Sept 2017, In: PLOS ONE. 12, 9, 12 p., e0181351.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Clonidine 100%
  • Randomized Trial 60%
  • clonidine 59%
  • Ropivacaine 59%
  • adjuvants 47%
  3 Citations (Scopus)

  87 Downloads (Pure)

• Does Dexmedetomidine Have a Perineural Mechanism of Action When Used as an Adjuvant to Ropivacaine? A Paired, Blinded, Randomized Trial in Healthy Volunteers

  Andersen, J. H., Grevstad, U., Siegel, H., Dahl, J. B., Mathiesen, O. & Jaeger, P., Jan 2017, In: Anesthesiology. 126, 1, p. 66-73 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ropivacaine 100%
  • Dexmedetomidine 97%
  • Healthy Volunteers 51%
  • Nerve Block 37%
  • Leg 35%
  30 Citations (Scopus)

• Dose-related beneficial and harmful effects of gabapentin in postoperative pain management: post hoc analyses from a systematic review with meta-analyses and trial sequential analyses

  Fabritius, M. L., Wetterslev, J., Mathiesen, O. & Dahl, J. B., 2017, In: Journal of Pain Research. 2017, 10, p. 2547-2563 17 p.

  Research output: Contribution to journal › Review › peer-review

  • Gabapentin 100%
  • Postoperative Pain 80%
  • Pain Management 80%
  • Meta-Analysis 59%
  • Systematic Reviews 58%
  11 Citations (Scopus)

  44 Downloads (Pure)

• Follow-up after intensive care treatment: a questionnaire survey of intensive care aftercare in Denmark

  Kjer, C. K. W., Estrup, S., Poulsen, L. M. & Mathiesen, O., Sept 2017, In: Acta Anaesthesiologica Scandinavica. 61, 8, p. 925-934

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Aftercare 100%
  • Denmark 90%
  • Critical Care 74%
  • Intensive Care Units 70%
  • Therapeutics 13%
  10 Citations (Scopus)

• Gabapentin in procedure-specific postoperative pain management: preplanned subgroup analyses from a systematic review with meta-analyses and trial sequential analyses

  Fabritius, M. L., Geisler, A., Petersen, P. L., Wetterslev, J., Mathiesen, O. & Dahl, J. B., 21 Jun 2017, In: B M C Anesthesiology. 17, 20 p., 85.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Gabapentin 100%
  • Postoperative Pain 80%
  • Pain Management 80%
  • Meta-Analysis 59%
  • Systematic Reviews 58%
  15 Citations (Scopus)

  77 Downloads (Pure)

• Improving Neuromuscular Monitoring and Reducing Residual Neuromuscular Blockade With E-Learning: Protocol for the Multicenter Interrupted Time Series INVERT Study

  Thomsen, J. L. D., Mathiesen, O., Hägi-Pedersen, D., Skovgaard, L. T., Østergaard, D., Engbaek, J. & Gätke, M. R., Oct 2017, In: J M I R Research Protocols. 6, 10, 8 p., e192.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Delayed Emergence from Anesthesia 100%
  • Neuromuscular Monitoring 99%
  • Interrupted Time Series Analysis 86%
  • Learning 45%
  • Hospital Anesthesia Department 27%
  61 Downloads (Pure)

• Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial

  Nielsen, R. V., Fomsgaard, J. S., Siegel, H., Martusevicius, R., Nikolajsen, L., Dahl, J. B. & Mathiesen, O., Mar 2017, In: Pain. 158, 3, p. 463-470 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Spinal Fusion 100%
  • Ketamine 90%
  • Chronic Pain 74%
  • Opioid Analgesics 72%
  • Morphine 51%
  60 Citations (Scopus)

• Low degree of satisfactory individual pain relief in post-operative pain trials

  Geisler, A., Dahl, J. B., Karlsen, A. P. H., Persson, E. & Mathiesen, O., 1 Jan 2017, In: Acta Anaesthesiologica Scandinavica. 61, 1, p. 83-90 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Pain 100%
  • Analgesics 33%
  • Meta-Analysis 28%
  • Pragmatic Clinical Trials 27%
  • Randomized Controlled Trials 25%
  6 Citations (Scopus)

• PANSAID - PAracetamol and NSAID in combination: study protocol for a randomised trial

  Thybo, K. H., Hägi-Pedersen, D., Wetterslev, J., Dahl, J. B., Schrøder, H. M., Bülow, H. H., Bjørck, J. G. & Mathiesen, O., 10 Jan 2017, In: Trials. 18, 10 p., 11.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Non-Steroidal Anti-Inflammatory Agents 100%
  • Acetaminophen 97%
  • Ibuprofen 54%
  • Arthroplasty 26%
  • Hip 22%
  6 Citations (Scopus)

  57 Downloads (Pure)

• PANSAID-PAracetamol and NSAID in combination: detailed statistical analysis plan for a randomised, blinded, parallel, four-group multicentre clinical trial

  Thybo, K. H., Jakobsen, J. C., Hägi-Pedersen, D., Pedersen, N. A., Dahl, J. B., Schrøder, H. M., Bülow, H. H., Bjørck, J. G., Overgaard, S., Mathiesen, O. & Wetterslev, J., 10 Oct 2017, In: Trials. 18, 7 p., 465.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Non-Steroidal Anti-Inflammatory Agents 100%
  • Acetaminophen 97%
  • Multicenter Studies 80%
  • Ibuprofen 65%
  • Clinical Trials 60%
  5 Citations (Scopus)

  54 Downloads (Pure)

• Postoperative pain treatment after total knee arthroplasty: A systematic review

  Karlsen, A. P. H., Wetterslev, M., Hansen, S. E., Hansen, M. S., Mathiesen, O. & Dahl, J. B., Mar 2017, In: PloS one. 12, 3, 53 p., e0173107.

  Research output: Contribution to journal › Review › peer-review

  • Postoperative Pain 100%
  • Analgesics 86%
  • Arthroplasty 73%
  • systematic review 67%
  • knees 61%
  58 Citations (Scopus)

  171 Downloads (Pure)
• 2016

  Gabapentin for post-operative pain management - a systematic review with meta-analyses and trial sequential analyses

  Fabritius, M. L., Geisler, A., Petersen, P. L., Nikolajsen, L., Hansen, M. S., Kontinen, V., Hamunen, K., Dahl, J. B., Wetterslev, J. & Mathiesen, O., Oct 2016, In: Acta Anaesthesiologica Scandinavica. 60, 9, p. 1188-1208 21 p.

  Research output: Contribution to journal › Review › peer-review

  • Gabapentin 100%
  • Pain Management 80%
  • Meta-Analysis 59%
  • Systematic Reviews 58%
  • Non-Narcotic Analgesics 32%
  55 Citations (Scopus)

• Lateral femoral cutaneous nerve block after total hip arthroplasty: a randomised trial

  Thybo, K. H., Mathiesen, O., Dahl, J. B., Schmidt, H. & Hägi-Pedersen, D., Oct 2016, In: Acta Anaesthesiologica Scandinavica. 60, 9, p. 1297-305 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Femoral Nerve 100%
  • Nerve Block 86%
  • Arthroplasty 71%
  • Hip 62%
  • Skin 41%
  15 Citations (Scopus)

• Post-operative analgesia: focus has been on benefit - are we forgetting the harm?

  Fabritius, M. L., Mathiesen, O., Wetterslev, J. & Dahl, J. B., 1 Aug 2016, In: Acta Anaesthesiologica Scandinavica. 60, 7, p. 839-41 3 p.

  Research output: Contribution to journal › Editorial

  8 Citations (Scopus)

• The effect of chlorzoxazone on acute pain after spine surgery: A randomized, blinded trial

  Nielsen, R. V., Fomsgaard, J. S., Siegel, M. H., Martusevicius, R., Mathiesen, O. & Dahl, J. B., 1 Sept 2016, In: Acta Anaesthesiologica Scandinavica. 60, 8, p. 1152-60 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Chlorzoxazone 100%
  • Acute Pain 65%
  • Spine 47%
  • Pain 22%
  • Placebos 21%
  5 Citations (Scopus)

• The effect of preoperative dexamethasone on pain 1 year after lumbar disc surgery: a follow-up study

  Nielsen, R. V., Fomsgaard, J., Mathiesen, O. & Dahl, J. B., 16 Nov 2016, In: B M C Anesthesiology. 16, 9 p., 112.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Dexamethasone 100%
  • Pain 62%
  • Placebos 53%
  • Diskectomy 38%
  • Leg 38%
  4 Citations (Scopus)

• Transversus abdominis plane block after laparoscopic colonic resection in cancer patients: A randomised clinical trial

  Torup, H., Hansen, E. G., Bøgeskov, M. B., Rosenberg, J., Mitchell, A. U., Petersen, P. L., Mathiesen, O., Dahl, J. B. & Møller, A. M., Oct 2016, In: European Journal of Anaesthesiology. 33, 10, p. 725-30 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Abdominal Muscles 100%
  • Randomized Controlled Trials 54%
  • Ibuprofen 38%
  • Acetaminophen 34%
  • Placebos 33%
  17 Citations (Scopus)
• 2015

  Effect of Adductor Canal Block Versus Femoral Nerve Block on Quadriceps Strength, Mobilization, and Pain After Total Knee Arthroplasty: A Randomized, Blinded Study

  Grevstad, J. U., Mathiesen, O., Valentiner, L. R. S., Jaeger, P., Hilsted, K. L. & Dahl, J. B., Jan 2015, In: Regional Anesthesia and Pain Medicine. 40, 1, p. 3-10 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Femoral Nerve 100%
  • Nerve Block 86%
  • Knee Replacement Arthroplasties 76%
  • Pain 43%
  • Ropivacaine 32%
  105 Citations (Scopus)

• Postoperative pain treatment after total hip arthroplasty: a systematic review

  Højer Karlsen, A. P., Geisler, A., Petersen, P. L., Mathiesen, O. & Dahl, J. B., Jan 2015, In: Pain. 156, 1, p. 8-30 23 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Postoperative Pain 100%
  • Arthroplasty 93%
  • Lumbosacral Plexus 88%
  • Analgesics 85%
  • Hip 81%
  77 Citations (Scopus)

• Preoperative dexamethasone reduces acute but not sustained pain after lumbar disk surgery: a randomized, blinded, placebo-controlled trial

  Nielsen, R. V., Siegel, H., Fomsgaard, J. S., Andersen, J. D. H., Martusevicius, R., Mathiesen, O. & Dahl, J. B., Dec 2015, In: Pain. 156, 12, p. 2538-44 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Dexamethasone 100%
  • Placebos 74%
  • Acute Pain 66%
  • Pain 62%
  • Vomiting 40%
  21 Citations (Scopus)
• 2013

  Adductor canal block versus femoral nerve block for analgesia after total knee arthroplasty: A Randomized, Double-blind Study

  Jaeger, P., Zaric, D., Fomsgaard, J. S., Hilsted, K. L., Bjerregaard, J., Gyrn, J., Mathiesen, O., Larsen, T. & Dahl, J. B., Nov 2013, In: Regional Anesthesia and Pain Medicine. 38, 6, p. 526-532 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Femoral Nerve 100%
  • Nerve Block 86%
  • Muscle Strength 76%
  • Knee Replacement Arthroplasties 76%
  • Double-Blind Method 73%
  207 Citations (Scopus)

• Bilateral transversus abdominis plane (TAP) block with 24 hours ropivacaine infusion via TAP catheters: A randomized trial in healthy volunteers

  Petersen, P. L., Hilsted, K. L., Dahl, J. B. & Mathiesen, O., 10 Oct 2013, In: B M C Anesthesiology. 13, October, p. 1-5 5 p., 30.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ropivacaine 100%
  • Abdominal Muscles 93%
  • Catheters 60%
  • Healthy Volunteers 51%
  • Pain Threshold 18%
  18 Citations (Scopus)
• 2010

  An expert opinion on postoperative pain management, with special reference to new developments

  Dahl, J. B., Mathiesen, O. & Kehlet, H., 1 Oct 2010, In: Expert Opinion on Pharmacotherapy. 11, 15, p. 2459-70 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Expert Testimony 100%
  • Postoperative Pain 96%
  • Pain Management 96%
  • Analgesics 82%
  • Pregabalin 32%
  37 Citations (Scopus)

• Multimodal analgesia with gabapentin, ketamine and dexamethasone in combination with paracetamol and ketorolac after hip arthroplasty: a preliminary study

  Rasmussen, M., Mathiesen, O., Dierking, G., Christensen, B. V., Hilsted, K. L., Larsen, T. K., Dahl, J. B., Christensen, B. V. & Larsen, T. K., 1 Apr 2010, In: European Journal of Anaesthesiology. 27, 4, p. 324-30 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ketorolac 100%
  • Gabapentin 90%
  • Ketamine 79%
  • Acetaminophen 76%
  • Arthroplasty 68%
  46 Citations (Scopus)

• The transversus abdominis plane block: a valuable option for postoperative analgesia? A topical review

  Petersen, P. L., Mathiesen, O., Torup, H. & Dahl, J. B., May 2010, In: Acta Anaesthesiologica Scandinavica. 54, 5, p. 529-35 7 p.

  Research output: Contribution to journal › Review › peer-review

  • Abdominal Muscles 100%
  • Analgesia 75%
  • Abdominal Wall 29%
  • Opioid Analgesics 24%
  • Pain 23%
  191 Citations (Scopus)
• 2008

  Pregabalin and dexamethasone for postoperative pain control: a randomized controlled study in hip arthroplasty

  Mathiesen, O., Jacobsen, L. S., Holm, H. E., Randall, S., Adamiec-Malmstroem, L., Graungaard, B. K., Holst, P. E., Hilsted, K. L. & Dahl, J. B., 2008, In: British Journal of Anaesthesia. 101, 4, p. 535-541 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  151 Citations (Scopus)