Ole Østergaard

2018

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Théry, C., Witwer, K. W., Aikawa, E., Alcaraz, M. J., Anderson, J. D., Andriantsitohaina, R., Antoniou, A., Arab, T., Archer, F., Atkin-Smith, G. K., Ayre, D. C., Bach, J.-M., Bachurski, D., Baharvand, H., Balaj, L., Baldacchino, S., Bauer, N. N., Baxter, A. A., Bebawy, M. & Beckham, C. & 31 others, Bedina Zavec, A., Benmoussa, A., Berardi, A. C., Bergese, P., Bielska, E., Blenkiron, C., Bobis-Wozowicz, S., Boilard, E., Boireau, W., Bongiovanni, A., Borràs, F. E., Bosch, S., Boulanger, C. M., Breakefield, X., Breglio, A. M., Brennan, M. Á., Brigstock, D. R., Brisson, A., Broekman, M. L., Bromberg, J. F., Bryl-Górecka, P., Buch, S., Buck, A. H., Burger, D., Busatto, S., Buschmann, D., Jørgensen, M. M., Jacobsen, S., Nejsum, P., Østergaard, O. & Xu, J., 1 Jan 2018, In: Journal of Extracellular Vesicles. 7, 1, p. 1-47 1535750.

Research output: Contribution to journal › Journal article › Research › peer-review

1914 Citations (Scopus)

75 Downloads (Pure)

2017

A review of studies of the proteomes of circulating microparticles: Key roles for galectin-3-binding protein-expressing microparticles in vascular diseases and systemic lupus erythematosus

Nielsen, C. T., Østergaard, O., Rasmussen, N. S., Jacobsen, S. & Heegaard, N. H. H., 2017, In: Clinical Proteomics. 14, 24 p., 11.

Research output: Contribution to journal › Review › peer-review

15 Citations (Scopus)

49 Downloads (Pure)

Biophysical comparison of diphtheria and tetanus toxins with the formaldehyde-detoxified toxoids, the main components of diphtheria and tetanus vaccines

Alsarraf, H., Dedic, E., Bjerrum, M. J., Østergaard, O., Kristensen, M. P., Petersen, J. W. & Jørgensen, R., 17 Nov 2017, In: Virulence. 8, 8, p. 1880-1889 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Distinct proteome pathology of circulating microparticles in systemic lupus erythematosus

Østergaard, O., Nielsen, C. T., Tanassi, J. T., Iversen, L. V., Jacobsen, S. & Heegaard, N. H. H., 21 Jun 2017, In: Clinical Proteomics. 14, 13 p., 23.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

156 Downloads (Pure)

Paucimannose-Rich N-glycosylation of Spatiotemporally Regulated Human Neutrophil Elastase Modulates Its Immune Functions

Loke, I., Østergaard, O., Heegaard, N. H. H., Packer, N. H. & Thaysen-Andersen, M., Aug 2017, In: Molecular and Cellular Proteomics. 16, 8, p. 1507-1527 21 p.

Research output: Contribution to journal › Journal article › Research › peer-review

27 Citations (Scopus)

2016

A Novel Fic (Filamentation Induced by cAMP) Protein from Clostridium difficile Reveals an Inhibitory Motif-independent Adenylylation/AMPylation Mechanism

Dedic, E., Alsarraf, H., Welner, D. H., Østergaard, O., Klychnikov, O. I., Hensbergen, P. J., Corver, J., van Leeuwen, H. C. & Jørgensen, R., 17 Jun 2016, In: The Journal of Biological Chemistry. 291, 25, p. 13286-13300 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Quantitative Protein Profiling of Chlamydia trachomatis Growth Forms Reveals Defense Strategies Against Tryptophan Starvation

Østergaard, O., Follmann, F., Olsen, A. W., Heegaard, N. H., Andersen, P. & Rosenkrands, I., Dec 2016, In: Molecular and Cellular Proteomics. 15, 12, p. 3540-3550 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

2015

Cross-sectional study of soluble selectins, fractions of circulating microparticles and their relationship to lung and skin involvement in systemic sclerosis

Iversen, L. V., Ullman, S., Østergaard, O., Nielsen, C. T., Halberg, P., Karlsmark, T., Heegaard, N. H. H. & Jacobsen, S., 12 Aug 2015, In: BMC Musculoskeletal Disorders. 16, 9 p., 191.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Galectin-3 binding protein links circulating microparticles with electron dense glomerular deposits in lupus nephritis

Nielsen, C. T., Østergaard, O., Rekvig, O. P., Sturfelt, G., Jacobsen, S. & Heegaard, N. H. H., 11 Oct 2015, In: Lupus. 24, 11, p. 1150-60

Research output: Contribution to journal › Journal article › Research › peer-review

38 Citations (Scopus)

Impact of microRNA-130a on the neutrophil proteome

Pedersen, C. C., Refsgaard, J. C., Østergaard, O., Jensen, L. J., Heegaard, N. H. H., Borregaard, N. & Cowland, J. B., 25 Nov 2015, In: B M C Immunology. 16, 10 p., 70.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Important options available--from start to finish--for translating proteomics results to clinical chemistry

Heegaard, N. H. H., Østergaard, O., Bahl, J. M. C., Overgaard, M., Beck, H. C., Rasmussen, L. M. & Larsen, M. R., 1 Feb 2015, In: Proteomics - Clinical Applications. 9, 1-2, p. 235-52 18 p.

Research output: Contribution to journal › Review › peer-review

7 Citations (Scopus)

2014

Filaggrin is a predominant member of the denaturation-resistant nickel-binding proteome of human epidermis

Ross-Hansen, K., Østergaard, O., Tanassi, J. T., Thyssen, J. P., Johansen, J. D., Menné, T. & Heegaard, N. H. H., Apr 2014, In: The Journal of Investigative Dermatology. 134, 4, p. 1164-1166 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

26 Citations (Scopus)

Papillon-Lefèvre syndrome patient reveals species-dependent requirements for neutrophil defenses

Sørensen, O. E., Clemmensen, S. N., Dahl, S. L., Østergaard, O., Heegaard, N. H. H., Glenthøj, A., Nielsen, F. C. & Borregaard, N., 1 Oct 2014, In: The Journal of Clinical Investigation. 124, 10, p. 4539-48 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

104 Citations (Scopus)

Plasma levels of galectin-3-binding protein reflect type I interferon activity and are increased in patients with systemic lupus erythematosus

Nielsen, C. T., Lood, C., Østergaard, O., Iversen, L. V., Voss, A., Bengtsson, A., Jacobsen, S. & Heegaard, N. H. H., 1 Jun 2014, In: Lupus Now. 1, p. 1-8 8 p., e000026.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Protein expression, characterization, crystallization and preliminary X-ray crystallographic analysis of a Fic protein from Clostridium difficile

Welner, D., Dedic, E., van Leeuwen, H. C., Kuijper, E., Bjerrum, M. J., Østergaard, O. & Jørgensen, R., Jun 2014, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 70, p. 827-831 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

2013

A heparin-based method for flow cytometric analysis of microparticles directly from platelet-poor plasma in calcium containing buffer

Iversen, L. V., Ostergaard, O., Nielsen, C., Jacobsen, S. & Heegaard, N. H. H., 28 Feb 2013, In: Journal of Immunological Methods. 388, 1-2, p. 49-59 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Circulating microparticles and plasma levels of soluble E- and P-selectins in patients with systemic sclerosis

Iversen, L., Østergaard, O., Ullman, S., Nielsen, C. T., Halberg, P., Karlsmark, T., Heegaard, N. H. H. & Jacobsen, S., 2013, In: Scandinavian Journal of Rheumatology. 42, 6, p. 473-482 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

Proteome profiling of human neutrophil granule subsets, secretory vesicles, and cell membrane: correlation with transcriptome profiling of neutrophil precursors

Rørvig, S., Østergaard, O., Heegaard, N. H. H. & Borregaard, N., Oct 2013, In: Journal of Leukocyte Biology. 94, 4, p. 711-721 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

133 Citations (Scopus)

Unique Protein Signature of Circulating Microparticles in Systemic Lupus Erythematosus

Østergaard, O., Nielsen, C., Iversen, L. V., Tanassi, J. T., Knudsen, S., Jacobsen, S. & Heegaard, N. H. H., Oct 2013, In: Arthritis & Rheumatism. 65, 10, p. 2680-2690 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

73 Citations (Scopus)

2012

Increased IgG on cell-derived plasma microparticles in systemic lupus erythematosus is associated with autoantibodies and complement activation

Nielsen, C. T., Østergaard, O., Stener, L., Iversen, L. V., Truedsson, L., Gullstrand, B., Jacobsen, S. & Heegaard, N. H. H., Apr 2012, In: Arthritis & Rheumatism. 64, 4, p. 1227-36 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

125 Citations (Scopus)

Quantitative proteome profiling of normal human circulating microparticles

Østergaard, O., Nielsen, C. T., Iversen, L. V., Jacobsen, S., Tanassi, J. T. & Heegaard, N. H. H., 6 Apr 2012, In: Journal of Proteome Research. 11, 4, p. 2154-63 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

37 Citations (Scopus)

2011

Alpha-1-antitrypsin is produced by human neutrophil granulocytes and their precursors and liberated during granule exocytosis

Clemmensen, S. N., Jacobsen, L. C., Rørvig, S., Askaa, B., Christenson, K., Iversen, M., Jørgensen, M. H., Larsen, M. T., van Deurs, B., Østergaard, O., Heegaard, N. H., Cowland, J. B. & Borregaard, N., 1 Jun 2011, In: European Journal of Haematology. 86, 6, p. 517-30 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

42 Citations (Scopus)

Distinct features of circulating microparticles and their relationship to clinical manifestations in systemic lupus erythematosus

Nielsen, C. T., Østergaard, O., Johnsen, C., Jacobsen, S. & Heegaard, N. H. H., Oct 2011, In: Arthritis & Rheumatism. 63, 10, p. 3067-77 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

92 Citations (Scopus)

2009

Integration of the barley genetic and seed proteome maps for chromosome 1H, 2H, 3H, 5H and 7H

Finnie, C., Bagge, M., Steenholdt, T., Østergaard, O., Bak-Jensen, K. S., Backes, G. M., Jensen, A., Giese, N. H., Larsen, J., Roepstorff, P. & Svensson, B., 2009, In: Functional & Integrative Genomics. 9, 1, p. 135-143 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

2007

Lysine 58-cleaved beta2-microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis-related amyloidosis

Giorgetti, S., Stoppini, M., Tennent, G. A., Relini, A., Marchese, L., Raimondi, S., Monti, M., Marini, S., Østergaard, O., Heegaard, N. H. H., Pucci, P., Esposito, G., Merlini, G. & Bellotti, V., Feb 2007, In: Protein Science. 16, 2, p. 343-9 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

Spatio-temporal profiling and degradation of alpha-amylase isozymes during barley seed germination

Bak-Jensen, K. S., Laugesen, S., Ostergaard, O., Finnie, C., Roepstorff, P. & Svensson, B., May 2007, In: F E B S Journal. 274, 10, p. 2552-65 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

39 Citations (Scopus)

2004

Aspects of the barley seed proteome during development and germination

Finnie, C., Maeda, K., ØStergaard, O., Bak-Jensen, K. S., Larsen, J. & Svensson, B., Jun 2004, In: Biochemical Society Transactions. 32, Pt3, p. 517-9 3 p.

Research output: Contribution to journal › Review › peer-review

57 Citations (Scopus)

Proteome analysis of barley seeds: Identification of major proteins from two-dimensional gels (pI 4-7)

Østergaard, O., Finnie, C. S., Laugesen, S., Roepstorff, P. & Svensson, B., 2004, In: Proteomics. 4, p. 2437-2447 11 p., https://doi.org/10.1002/pmic.200300753.

Research output: Contribution to journal › Journal article › Research › peer-review

115 Citations (Scopus)

2003

Identification, cloning and characterization of two thioredoxin h isoforms, HvTrxh1 and HvTrxh2, from the barley seed proteome

Maeda, K., Finnie, C., ØStergaard, O. & Svensson, B., Jun 2003, In: European Journal of Biochemistry. 270, 12, p. 2633-43 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

50 Citations (Scopus)

2002

Initial proteome analysis of mature barley seeds and malt

Østergaard, O., Melchior, S., Roepstorff, P. & Svensson, B., Jun 2002, In: Proteomics. 2, 6, p. 733-9 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

91 Citations (Scopus)

Ole Østergaard

Research output

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