Research output per year
Research output per year
Personal profile
CV
September 2016- : Assistant Professor, CNS Drug Delivery & Barrier Modelling, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen
April 2015-August 2016: Postdoc, Section for Biologics, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen
April 2011-March 2015: PhD fellow, Section for Biologics, Department of Pharmacy & the Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen (8 months maternity leave)
March 2010-March 2011: Scientific assistant, Group of Developmental Neurobiology, Max Delbrück Center for Molecular Medicine, Berlin,
February 2009-March 2010: Master’s student, Group of Developmental Neurobiology, Max Delbrück Center for Molecular Medicine, Berlin
Primary fields of research
My main focus is delivery of therapeutic peptides and proteins across biological barriers mediated by carrier peptides, such as cell penetrating peptides (CPPs) and tight junction modulating peptides (TJMPs).
This includes subprojects investigating 1) the effect of covalent conjugation of the carrier peptide to the therapeutic peptide or protein, 2) intermolecular interactions controlling carrier peptide-therapeutic peptide/protein nanocomplexation, and 3) mechanistic understanding of cellular events leading to delivery across biological barriers.
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Dive into the research topics where Mie Kristensen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Two-photon fluorescence imaging: a platform to investigate cell-penetrating peptides and liposome-based nanocarriers for drug delivery across the heterogeneous BBB in vivo
Kucharz, K., Kristensen, K., Kristensen, M., Lund, M., Andresen, T., Brodin, B. & Lauritzen, M., 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, p. 60 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Cellular effects and delivery propensity of penetratin is influenced by conjugation to parathyroid hormone fragment 1-34 in synergy with pH
Kristensen, M., Nielsen, L. H., Zor, K., Boisen, A., Christensen, M. V., Berthelsen, J. & Nielsen, H. M., 21 Feb 2018, In: Bioconjugate Chemistry. 29, 2, p. 371-381Research output: Contribution to journal › Journal article › Research › peer-review
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Routes for drug translocation across the blood-brain barrier: Exploiting peptides as delivery vectors
Kristensen, M. & Brodin, B., Sept 2017, In: Journal of Pharmaceutical Sciences. 106, 9, p. 2326-2334Research output: Contribution to journal › Review › peer-review
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Applications and Challenges for Use of Cell-Penetrating Peptides as Delivery Vectors for Peptide and Protein Cargos
Kristensen, M., Birch, D. & Mørck Nielsen, H., 30 Jan 2016, In: International Journal of Molecular Sciences . 17, 2, p. 1-17 17 p., 185.Research output: Contribution to journal › Review › peer-review
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Cell-Penetrating Peptides as Carriers for Oral Delivery of Biopharmaceuticals
Kristensen, M. & Nielsen, H. M., 1 Feb 2016, In: Basic & Clinical Pharmacology & Toxicology Online. 118, 2, p. 99-106 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cell-penetrating peptides as tools to enhance non-injectable delivery of biopharmaceuticals
Kristensen, M. & Nielsen, H. M., 2 Apr 2016, In: Tissue Barriers. 4, 2, 15 p., e1178369.Research output: Contribution to journal › Review › peer-review
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Carrier peptide-mediated transepithelial permeation of biopharmaceuticals: Effect of co-administration versus direct conjugation
Kristensen, M. & Nielsen, H. M., 2015.Research output: Contribution to conference › Poster › Research › peer-review
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Cell-penetrating peptides as carriers for transepithelial drug delivery in vitro
Rønholt, S., Kristensen, M. & Nielsen, H. M., 2015, Cell-penetrating peptides : Methods and Protocols. Langel, Ü. (ed.). Vol. 1324. p. 261-277 17 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Activities
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Benzon Symposium 63 – New Paradigms of Protein Engineering
Mie Kristensen (Participant)
2017 → …Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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20th Symposium on Signal Transduction at the Blood-Brain Barrier
Mie Kristensen (Participant)
2017 → …Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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19th Symposium in Signal Transduction
Mie Kristensen (Participant)
2016 → …Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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Cold Spring Harbor
Mie Kristensen (Participant)
2016 → …Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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Crossing Biological Barriers
Mie Kristensen (Participant)
9 Nov 2015 → 11 Nov 2015Activity: Participating in or organising an event types › Organisation of and participation in conference
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Annual Controlled Release Society meeting
Mie Kristensen (Participant)
26 Jul 2015 → 29 Jul 2015Activity: Participating in or organising an event types › Organisation of and participation in conference
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From Cell-Penetrating Peptides to Nanoparticles for Cellular Delivery
Mie Kristensen (Participant)
1 Jul 2015 → 3 Jul 2015Activity: Participating in or organising an event types › Organisation of and participation in conference
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Electron Microscopy
Mie Kristensen (Participant)
2014 → …Activity: Participating in or organising an event types › Participation in workshop, seminar, course