Jakob Grunnet Knudsen

2019

Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production

Knudsen, J. G., Hamilton, A., Ramracheya, R., Tarasov, A. I., Brereton, M., Haythorne, E., Chibalina, M. V., Spégel, P., Mulder, H., Zhang, Q., Ashcroft, F. M., Adam, J. & Rorsman, P., 5 Feb 2019, In: Cell Metabolism. 29, 2, p. 430-442, e1-e4

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

2 Downloads (Pure)

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion

Vergari, E., Knudsen, J. G., Ramracheya, R., Salehi, A., Zhang, Q., Adam, J., Asterholm, I. W., Benrick, A., Briant, L. J. B., Chibalina, M. V., Gribble, F. M., Hamilton, A., Hastoy, B., Reimann, F., Rorsman, N. J. G., Spiliotis, I. I., Tarasov, A., Wu, Y., Ashcroft, F. M. & Rorsman, P., 1 Dec 2019, In: Nature Communications. 10, 11 p., 139.

Research output: Contribution to journal › Journal article › Research › peer-review

49 Citations (Scopus)

β Cell Dysfunction in Type 2 Diabetes: Drained of Energy?

Knudsen, J. G. & Rorsman, P., 8 Jan 2019, In: Cell Metabolism. 29, 1, p. 1-2 2 p.

Research output: Contribution to journal › Editorial › peer-review

3 Citations (Scopus)

2018

Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca²⁺ Mobilization From Acidic Stores in Pancreatic α-Cells

Hamilton, A., Zhang, Q., Salehi, A., Willems, M., Knudsen, J. G., Ringgaard, A. K., Chapman, C. E., Gonzalez-Alvarez, A., Surdo, N. C., Zaccolo, M., Basco, D., Johnson, P. R. V., Ramracheya, R., Rutter, G. A., Galione, A., Rorsman, P. & Tarasov, A. I., 1 Jun 2018, In: Diabetes. 67, 6, p. 1128-1139

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

CPT1a-Dependent Long-Chain Fatty Acid Oxidation Contributes to Maintaining Glucagon Secretion from Pancreatic Islets

Briant, L. J. B., Dodd, M. S., Chibalina, M. V., Rorsman, N. J. G., Johnson, P. R. V., Carmeliet, P., Rorsman, P. & Knudsen, J. G., 12 Jun 2018, In: Cell Reports. 23, 11, p. 3300-3311 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

2 Downloads (Pure)

Impact of fasting followed by short-term exposure to interleukin-6 on cytochrome P450 mRNA in mice

Rasmussen, M. K., Bertholdt, L., Gudiksen, A., Pilegaard, H. & Knudsen, J. G., 5 Jan 2018, In: Toxicology Letters. 282, p. 93-99 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Skeletal Muscle Interleukin-6 Regulates Hepatic Cytochrome P450 Expression: Effects of 16-Week High-Fat Diet and Exercise

Knudsen, J. G., Bertholdt, L., Gudiksen, A., Gerbal-Chaloin, S. & Rasmussen, M. K., 1 Mar 2018, In: Toxicological Sciences. 162, 1, p. 309-317 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

2017

Lack of skeletal muscle IL-6 influences hepatic glucose metabolism in mice during prolonged exercise

Bertholdt, L., Gudiksen, A., Schwartz, C. L., Knudsen, J. G. & Pilegaard, H., 7 Apr 2017, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 312, 4, p. R626-R636 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Skeletal muscle IL-6 regulates muscle substrate utilization and adipose tissue metabolism during recovery from an acute bout of exercise

Knudsen, J. G., Gudiksen, A., Bertholdt, L., Overby, P., Villesen, I., Schwartz, C. L. & Pilegaard, H., 18 Dec 2017, In: PLoS ONE. 12, 12, 19 p., e0189301.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

129 Downloads (Pure)

2016

Lack of skeletal muscle IL-6 affects pyruvate dehydrogenase activity at rest and during prolonged exercise

Gudiksen, A., Schwartz, C. L., Bertholdt, L., Joensen, E., Knudsen, J. G. & Pilegaard, H., Jun 2016, In: P L o S One. 11, 6, 17 p., e0156460.

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

67 Downloads (Pure)

Skeletal muscle IL-6 and regulation of liver metabolism during high-fat diet and exercise training

Knudsen, J. G., Joensen, E., Bertholdt, L., Jessen, H., van Hauen, L., Hidalgo, J. & Pilegaard, H., 1 May 2016, In: Physiological Reports. 4, 9, 9 p., e12788.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

83 Downloads (Pure)

2015

Exercise-induced regulation of key factors in substrate choice and gluconeogenesis in mouse liver

Knudsen, J. G., Biensø, R. S., Hassing, H. A., Jakobsen, A. H. & Pilegaard, H., 1 May 2015, In: Molecular and Cellular Biochemistry. 403, 1-2, p. 209-217 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Skeletal muscle interleukin-6 regulates metabolic factors in iWAT during HFD and exercise training

Knudsen, J. G., Bertholdt, L., Joensen, E., Lassen, S. B., Hidalgo, J. & Pilegaard, H., 1 Aug 2015, In: Obesity. 23, 8, p. 1616-1624 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

2014

Effects of IL-6 on pyruvate dehydrogenase regulation in mouse skeletal muscle

Biensø, R. S., Knudsen, J. G., Brandt, N., Pedersen, P. A. & Pilegaard, H., Aug 2014, In: Pflügers Archiv - European Journal of Physiology. 466, 8, p. 1647-1657 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

793 Downloads (Pure)

Role of IL-6 in exercise training- and cold-induced UCP1 expression in subcutaneous white adipose tissue

Knudsen, J. G., Murholm, M., Carey, A. L., Biensø, R. S., Basse, A. L., Allen, T. L., Hidalgo, J., Kingwell, B. A., Febbraio, M. A., Hansen, J. B. & Pilegaard, H., 8 Jan 2014, In: P L o S One. 9, 1, 8 p., e84910.

Research output: Contribution to journal › Journal article › Research › peer-review

109 Citations (Scopus)

1402 Downloads (Pure)

Skeletal Muscle Derived IL-6 in Liver and Adipose Tissue Metabolism

Knudsen, J. G., 2014, Department of Biology, Faculty of Science, University of Copenhagen.

Research output: Book/Report › Ph.D. thesis

2013

PGC-1α Is Required for Exercise- and Exercise Training-Induced UCP1 Up-Regulation in Mouse White Adipose Tissue.

Jørgensen, S. R., Grunnet Knudsen, J., Leick, L., Lundgaard, A., Munk Nielsen, M. & Pilegaard, H., 22 May 2013, In: PloS one. 8, 5, p. 1-6 6 p., e64123.

Research output: Contribution to journal › Journal article › Research › peer-review

46 Citations (Scopus)

838 Downloads (Pure)

2010

PGC-1α is required for AICAR induced expression of GLUT4 and mitochondrial proteins in mouse skeletal muscle

Leick, L., Fentz, J., Biensø, R. S., Knudsen, J. G., Jeppesen, J., Kiens, B., Wojtaszewski, J. & Pilegaard, H., Sept 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 3, p. E456-E465 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

69 Citations (Scopus)

Jakob Grunnet Knudsen

Research output

Search results