Erika Villanueva - Research output - University of Copenhagen Research Portal

Research activity per year

7 Journal article
1 Poster

8 results

2018

ANTIBODIES INHIBIT CELL TO CELL TRANSMISSION OF MUTANT HTT
Bartl, S., Oueslati, A., Southwell, A. L., Parth, M., Salhat, N., Siddu, A., Burkert, M., Pankevych, H., David, L., Villanueva, E. B., Xie, Y., Dal Cengio, L., Ko, S., Hayden, M. R., Cicchetti, F. & Smrzka, O. W., Sept 2018, p. A91-A91.
Research output: Contribution to conference › Poster › Research
HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo
Ehrnhoefer, D. E., Southwell, A. L., Sivasubramanian, M., Qiu, X., Villanueva, E. B., Xie, Y., Waltl, S., Anderson, L., Fazeli, A., Casal, L., Felczak, B., Tsang, M. & Hayden, M. R., 15 Jan 2018, In: Human Molecular Genetics. 27, 2, p. 239-253 15 p.
Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus)
Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease
Southwell, A. L., Kordasiewicz, H. B., Langbehn, D., Skotte, N. H., Parsons, M. P., Villanueva, E. B., Caron, N. S., Østergaard, M. E., Anderson, L. M., Xie, Y., Cengio, L. D., Findlay-Black, H., Doty, C. N., Fitsimmons, B., Swayze, E. E., Seth, P. P., Raymond, L. A., Frank Bennett, C. & Hayden, M. R., 2018, In: Science Translational Medicine. 10, 461, p. 1-12 eaar3959.
Research output: Contribution to journal › Journal article › Research › peer-review
44 Citations (Scopus)
2017
A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles
Southwell, A. L., Skotte, N. H., Villanueva, E. B., Østergaard, M. E., Gu, X., Kordasiewicz, H. B., Kay, C., Cheung, D., Xie, Y., Waltl, S., Dal Cengio, L., Findlay-Black, H., Doty, C. N., Petoukhov, E., Iworima, D., Slama, R., Ooi, J., Pouladi, M. A., Yang, X. W., Swayze, E. E., & 2 othersSeth, P. P. & Hayden, M. R., 15 Mar 2017, In: Human Molecular Genetics. 26, 6, p. 1115-1132 18 p.
Research output: Contribution to journal › Journal article › Research › peer-review
11 Citations (Scopus)
2014
In vivo evaluation of candidate allele-specific mutant huntingtin gene silencing antisense oligonucleotides
Southwell, A. L., Skotte, N. H., Kordasiewicz, H. B., Østergaard, M. E., Watt, A. T., Carroll, J. B., Doty, C. N., Villanueva, E. B., Petoukhov, E., Vaid, K., Xie, Y., Freier, S. M., Swayze, E. E., Seth, P. P., Bennett, C. F. & Hayden, M. R., 11 Dec 2014, In: Molecular Therapy. 22, 12, p. 2093-106 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
82 Citations (Scopus)
2013
A fully humanized transgenic mouse model of Huntington disease
Southwell, A. L., Warby, S. C., Carroll, J. B., Doty, C. N., Skotte, N. H., Zhang, W., Villanueva, E. B., Kovalik, V., Xie, Y., Pouladi, M. A., Collins, J. A., Yang, X. W., Franciosi, S. & Hayden, M. R., 1 Jan 2013, In: Human Molecular Genetics. 22, 1, p. 18-34 17 p.
Research output: Contribution to journal › Journal article › Research › peer-review
48 Citations (Scopus)
Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS
Østergaard, M. E., Southwell, A. L., Kordasiewicz, H., Watt, A. T., Skotte, N. H., Doty, C. N., Vaid, K., Villanueva, E. B., Swayze, E. E., Bennett, C. F., Hayden, M. R. & Seth, P. P., Nov 2013, In: Nucleic Acids Research. 41, 21, p. 9634-50 17 p.
Research output: Contribution to journal › Journal article › Research › peer-review
105 Citations (Scopus)
2012
Secreted phospholipase A2 group IIA is a neurotoxin released by stimulated human glial cells
Villanueva, E. B., Little, J. P., Lambeau, G. & Klegeris, A., Apr 2012, In: Molecular and Cellular Neuroscience.
Research output: Contribution to journal › Journal article › Research › peer-review
12 Citations (Scopus)