Anne-Marie Axø Gerdes

Research output

Research output per year 2000 2011 2012 2013 2015 2016 2017 2018 2019

• 92 Journal article
• 2 Book chapter
• 2 Letter
• 2 Review
• 2 More
  • 1 Comment/debate
  • 1 Editorial

Research output per year

Research output per year

Search results

• 2014

  DNA Glycosylases Involved in Base Excision Repair May Be Associated with Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

  Osorio, A., Milne, R. L., Kuchenbaecker, K., Vaclová, T., Pita, G., Alonso, R., Peterlongo, P., Blanco, I., de la Hoya, M., Duran, M., Díez, O., Ramón Y Cajal, T., Konstantopoulou, I., Martínez-Bouzas, C., Andrés Conejero, R., Soucy, P., McGuffog, L., Barrowdale, D., Lee, A., Swe-Brca, & 180 othersArver, B., Rantala, J., Loman, N., Ehrencrona, H., Olopade, O. I., Beattie, M. S., Domchek, S. M., Nathanson, K., Rebbeck, T. R., Arun, B. K., Karlan, B. Y., Walsh, C., Lester, J., John, E. M., Whittemore, A. S., Daly, M. B., Southey, M., Hopper, J., Terry, M. B., Buys, S. S., Janavicius, R., Dorfling, C. M., van Rensburg, E. J., Steele, L., Neuhausen, S. L., Ding, Y. C., Hansen, T. V. O., Jønson, L., Ejlertsen, B., Gerdes, A-M., Infante, M., Herráez, B., Moreno, L. T., Weitzel, J. N., Herzog, J., Weeman, K., Manoukian, S., Peissel, B., Zaffaroni, D., Scuvera, G., Bonanni, B., Mariette, F., Volorio, S., Viel, A., Varesco, L., Papi, L., Ottini, L., Tibiletti, M. G., Radice, P., Yannoukakos, D., Garber, J., Ellis, S., Frost, D., Platte, R., Fineberg, E., Evans, G., Lalloo, F., Izatt, L., Eeles, R., Adlard, J., Davidson, R., Cole, T., Eccles, D., Cook, J., Hodgson, S., Brewer, C., Tischkowitz, M., Douglas, F., Porteous, M., Side, L., Walker, L., Morrison, P., Donaldson, A., Kennedy, J., Foo, C., Godwin, A. K., Schmutzler, R. K., Wappenschmidt, B., Rhiem, K., Engel, C., Meindl, A., Ditsch, N., Arnold, N., Plendl, H. J., Niederacher, D., Sutter, C., Wang-Gohrke, S., Steinemann, D., Preisler-Adams, S., Kast, K., Varon-Mateeva, R., Gehrig, A., Stoppa-Lyonnet, D., Sinilnikova, O. M., Mazoyer, S., Damiola, F., Poppe, B., Claes, K., Piedmonte, M., Tucker, K., Backes, F., Rodríguez, G., Brewster, W., Wakeley, K., Rutherford, T., Caldés, T., Nevanlinna, H., Aittomäki, K., Rookus, M. A., van Os, T. A. M., van der Kolk, L., de Lange, J. L., Meijers-Heijboer, H. E. J., van der Hout, A. H., van Asperen, C. J., Gómez Garcia, E. B., Hoogerbrugge, N., Collée, J. M., van Deurzen, C. H. M., van der Luijt, R. B., Devilee, P., Hebon, Olah, E., Lázaro, C., Teulé, A., Menéndez, M., Jakubowska, A., Cybulski, C., Gronwald, J., Lubinski, J., Durda, K., Jaworska-Bieniek, K., Johannsson, O. T., Maugard, C., Montagna, M., Tognazzo, S., Teixeira, M. R., Healey, S., Investigators, K., Olswold, C., Guidugli, L., Lindor, N., Slager, S., Szabo, C. I., Vijai, J., Robson, M., Kauff, N., Zhang, L., Rau-Murthy, R., Fink-Retter, A., Singer, C. F., Rappaport, C., Geschwantler Kaulich, D., Pfeiler, G., Tea, M-K., Berger, A., Phelan, C. M., Greene, M. H., Mai, P. L., Lejbkowicz, F., Andrulis, I., Mulligan, A. M., Glendon, G., Toland, A. E., Bojesen, A., Pedersen, I. S., Sunde, L., Thomassen, M., Kruse, T. A., Jensen, U. B., Friedman, E., Laitman, Y., Shimon, S. P., Simard, J., Easton, D. F., Offit, K., Couch, F. J., Chenevix-Trench, G., Antoniou, A. C. & Benitez, J., Apr 2014, In: P L o S Genetics. 10, 4, p. 1-12 12 p., e1004256.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • DNA Glycosylases 100%
  • glycosylases 97%
  • cancer risk 78%
  • DNA repair 74%
  • mutation 68%
  28 Citations (Scopus)

• Functional characterization of BRCA1 gene variants by mini-gene splicing assay

  Steffensen, A. Y., Dandanell, M., Jønson, L., Ejlertsen, B., Gerdes, A-M., Nielsen, F. C. & Hansen, T. VO., 1 Dec 2014, In: European Journal of Human Genetics. 22, 12, p. 1362-1368 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • BRCA1 Gene 100%
  • Computer Simulation 51%
  • Genes 29%
  • RNA 25%
  • Genetic Counseling 20%
  39 Citations (Scopus)

• Hereditary breast cancer: clinical, pathological and molecular characteristics

  Larsen, M. J., Thomassen, M., Gerdes, A-M. & Kruse, T. A., 15 Oct 2014, In: Breast Cancer: Basic and Clinical Research. 8, p. 145-155 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Breast Neoplasms 100%
  • Mutation 87%
  • Genetic Background 55%
  • Gene Expression Profiling 53%
  • Patient Selection 45%
  46 Citations (Scopus)

• Is Colorectal Neoplasia Part of the Birt-Hogg-Dub Syndrome?

  Boman, P. S., Ousager, L. B., Friis-Hansen, L., Hansen, T. V. O., Broesby-Olsen, S. & Gerdes, A-M. A., 2014, In: Journal of Gastroenterology and Hepatology Research. 3, 4, p. 1039-1042 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Prophylactic total gastrectomy in hereditary diffuse gastric cancer: identification of two novel CDH1 gene mutations-a clinical observational study

  Bardram, L., Hansen, T. V. O., Gerdes, A-M., Timshel, S., Friis-Hansen, L. & Federspiel, B., Jun 2014, In: Familial Cancer. 13, 2, p. 231-242 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Gastrectomy 100%
  • Stomach Neoplasms 83%
  • Observational Studies 75%
  • Clinical Studies 67%
  • Mutation 54%
  20 Citations (Scopus)

• RNA profiling reveals familial aggregation of molecular subtypes in non-BRCA1/2 breast cancer families

  Larsen, M. J., Thomassen, M., Tan, Q., Lænkholm, A-V., Bak, M., Sørensen, K. P., Andersen, M. K., Kruse, T. A. & Gerdes, A-M., 31 Jan 2014, In: B M C Medical Genomics. 7, p. 9

  Research output: Contribution to journal › Journal article › Research › peer-review

  • RNA 100%
  • Breast Neoplasms 92%
  • Neoplasms 21%
  • Biopsy 13%
  • Phenotype 13%
  12 Citations (Scopus)
• 2013

  A BAP1 Mutation in a Danish Family Predisposes to Uveal Melanoma and Other Cancers

  Aoude, L. G., Wadt, K., Bojesen, A., Cr�ger, D. G., Borg, A., Trent, J. M., Brown, K. M., Gerdes, A-M., Jönsson, G. & Hayward, N. K., Aug 2013, In: P L o S One. 8, 8, p. 1-5 5 p., e72144.

  Research output: Contribution to journal › Journal article › Research › peer-review

  47 Citations (Scopus)

• Classifications within molecular subtypes enables identification of BRCA1/BRCA2 mutation carriers by RNA tumor profiling

  Larsen, M. J., Kruse, T. A., Tan, Q., Lænkholm, A-V., Bak, M., Lykkesfeldt, A. E., Sørensen, K. P., Hansen, T. V. O., Ejlertsen, B., Gerdes, A-M. & Thomassen, M., 21 May 2013, In: P L o S One. 8, 5, 12 p., e64268.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Profiling 100%
  • RNA 85%
  • Tumor 75%
  • tumor 74%
  • Tumors 72%
  59 Citations (Scopus)

• Functional examination of MLH1, MSH2, and MSH6 intronic mutations identified in Danish colorectal cancer patients

  Petersen, S. M., Dandanell, M., Rasmussen, L. J., Gerdes, A-M., Krogh, L. N., Bernstein, I., Okkels, H., Wikman, F., Nielsen, F. C. & Hansen, T. V. O., 3 Oct 2013, In: BMC Medical Genetics. 14, p. 103

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Colorectal Neoplasms 100%
  • Mutation 70%
  • Computer Simulation 44%
  • Hereditary Nonpolyposis Colorectal Neoplasms 41%
  • Frameshift Mutation 19%
  16 Citations (Scopus)

• Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk

  Couch, F. J., Gerdes, A-M. A., Nielsen, F. C. & al., E., Mar 2013, In: P L o S Genetics. 9, 3, p. 1-21 21 p., e1003212.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • ovarian neoplasms 100%
  • genome-wide association study 80%
  • cancer risk 79%
  • breast neoplasms 79%
  • Genome-Wide Association Study 72%
  195 Citations (Scopus)

• Genomsekventering – klinisk anvendelse

  Translated title of the contribution: Genome sequencing--clinical useHertz, J. M., Gerdes, A-M., Grønskov, K., Thomassen, M. & Vogel, I., 18 Mar 2013, In: Ugeskrift for Laeger. 175, 12, p. 818 1 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  1 Citation (Scopus)

• Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

  Bojesen, S. E., Pooley, K. A., Johnatty, S. E., Beesley, J., Michailidou, K., Tyrer, J. P., Edwards, S. L., Pickett, H. A., Shen, H. C., Smart, C. E., Hillman, K. M., Mai, P. L., Lawrenson, K., Stutz, M. D., Lu, Y., Karevan, R., Woods, N., Johnston, R. L., French, J. D., Chen, X., & 31 othersWeischer, M., Nielsen, S. F., Maranian, M. J., Ghoussaini, M., Ahmed, S., Baynes, C., Bolla, M. K., Wang, Q., Dennis, J., McGuffog, L., Barrowdale, D., Lee, A. R., Healey, S., Lush, M., Tessier, D. C., Vincent, D., Bacot, F., Vergote, I., Lambrechts, S., Despierre, E., Risch, H. A., González-Neira, A., Rossing, M. A., Pita, G., Doherty, J. A., Alvarez, N., Nordestgaard, B. G., Engelholm, S. A., Høgdall, C. K., Gerdes, A-M. & Australian Cancer Study, Apr 2013, In: Nature Genetics. 45, 4, p. 371-84, 384e1-2

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Telomere 100%
  • Ovarian Neoplasms 82%
  • Single Nucleotide Polymorphism 76%
  • Breast Neoplasms 58%
  • Alleles 53%
  393 Citations (Scopus)

• Tamoxifen and Risk of Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

  Phillips, K-A., Milne, R. L., Rookus, M. A., Daly, M. B., Antoniou, A. C., Peock, S., Frost, D., Easton, D. F., Ellis, S., Friedlander, M. L., Buys, S. S., Andrieu, N., Noguès, C., Stoppa-Lyonnet, D., Bonadona, V., Pujol, P., McLachlan, S. A., John, E. M., Hooning, M. J., Seynaeve, C., & 16 othersTollenaar, R. A. E. M., Goldgar, D. E., Terry, M. B., Caldes, T., Weideman, P. C., Andrulis, I. L., Singer, C. F., Birch, K., Simard, J., Southey, M. C., Olsson, H. L., Jakubowska, A., Olah, E., Gerdes, A-M., Foretova, L. & Hopper, J. L., 1 Sept 2013, In: Journal of Clinical Oncology. 31, 25, p. 3091-3099 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Tamoxifen 100%
  • Breast Neoplasms 60%
  • Mutation 52%
  • Unilateral Breast Neoplasms 15%
  • Familial Breast Cancer 15%
  130 Citations (Scopus)

• Von Hippel-Lindau disease (vHL)

  Binderup, M. L. M., Bisgaard, S. M. L., Harbud, V., Møller, H. U., Gimsing, S., Friis-Hansen, L., Hansen, T. V. O., Bagi, P., Knigge, U., Kosteljanetz, M., Bøgeskov, L., Thomsen, C., Gerdes, A-M., Ousager, L. B. & Sunde, L., Dec 2013, In: Danish Medical Journal. 60, 12, p. B4763

  Research output: Contribution to journal › Journal article › Research › peer-review

  • von Hippel-Lindau Disease 100%
  • Islet cell tumor syndrome 14%
  • Normetanephrine 13%
  • Metanephrine 12%
  • Hemangioblastoma 12%
  49 Citations (Scopus)
• 2012

  A cryptic BAP1 splice mutation in a family with uveal and cutaneous melanoma, and paraganglioma.

  Wadt, K., Choi, J., Chung, J. Y., Kiilgaard, J. F., Heegaard, S., Drzewiecki, K. T. M., Trent, J. M., Hewitt, S. M., Hayward, N. K., Gerdes, A-M. A. & Brown, K. M., Nov 2012, In: Pigment Cell & Melanoma Research. 25, 6, p. 815-818 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • BRCA1 Protein 100%
  • Uveal melanoma 88%
  • Paraganglioma 85%
  • Mutation 56%
  • Melanoma 55%
  86 Citations (Scopus)

• A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers

  Ding, Y. C., McGuffog, L., Healey, S., Friedman, E., Laitman, Y., Paluch-Shimon, S., Kaufman, B., Liljegren, A., Lindblom, A., Olsson, H., Kristoffersson, U., Stenmark-Askmalm, M., Melin, B., Domchek, S. M., Nathanson, K. L., Rebbeck, T. R., Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., & 31 othersGronwald, J., Huzarski, T., Cybulski, C., Byrski, T., Osorio, A., Cajal, T. R., Stavropoulou, A. V., Benítez, J., Hamann, U., Rookus, M., Aalfs, C. M., de Lange, J. L., Meijers-Heijboer, H. E. J., Oosterwijk, J. C., van Asperen, C. J., Gómez García, E. B., Hoogerbrugge, N., Jager, A., van der Luijt, R. B., Easton, D. F., Peock, S., Frost, D., Ellis, S. D., Platte, R., Fineberg, E., Evans, D. G., Lalloo, F., Izatt, L., Eeles, R., Gerdes, A-M. & SWE-BRCA, Aug 2012, In: Cancer Epidemiology, Biomarkers & Prevention. 21, 8, p. 1362-70 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Insulin Receptor Substrate Proteins 100%
  • Ovarian Neoplasms 70%
  • Breast Neoplasms 49%
  • Mutation 43%
  • Confidence Intervals 16%
  17 Citations (Scopus)

• Awareness of endometrial cancer risk and compliance with screening in hereditary nonpolyposis colorectal cancer

  Ketabi, Z., Mosgaard, B. J., Gerdes, A-M., Ladelund, S. & Bernstein, I. T., Nov 2012, In: Obstetrics and Gynecology. 120, 5, p. 1005-12 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Hereditary Nonpolyposis Colorectal Neoplasms 100%
  • Endometrial Neoplasms 78%
  • Logistic Models 22%
  • Genetic Counseling 9%
  • Denmark 8%
  15 Citations (Scopus)

• Cancergenetik - arvelig disposition for cancer

  Gerdes, A-M. A., 2012, Medicinsk genetik. Nørby, S. & Jensen, P. K. A. (eds.). 2 ed. København, p. 231-254

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

• Clinical genetics in Denmark

  Gerdes, A-M. A., 2012, In: BSHG News. 46, p. 61-62

  Research output: Contribution to journal › Journal article › Research

• Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers

  Antoniou, A. C., Kuchenbaecker, K. B., Soucy, P., Beesley, J., Chen, X., McGuffog, L., Lee, A. R., Barrowdale, D., Healey, S., Sinilnikova, O. M., Caligo, M. A., Loman, N., Harbst, K., Lindblom, A., Arver, B., Rosenquist, R., Karlsson, P. W., Nathanson, K., Domchek, S., Rebbeck, T., & 31 othersJakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Złowowcka-Perłowska, E., Osorio, A., Durán, M., Andrés, R., Benítez, J., Hamann, U., Hogervorst, F. B., van Os, T. A., Verhoef, S., Meijers-Heijboer, H. E. J., Wijnen, J., Gómez Garcia, E. B., Ligtenberg, M. J., Kriege, M., Collée, J. M., Ausems, M. G. E. M., Oosterwijk, J. C., Peock, S., Frost, D., Ellis, S. D., Platte, R., Fineberg, E., Evans, D. G., Lalloo, F., Nielsen, F. C., Gerdes, A-M. & CIMBA, SWE-BRCA, 20 Feb 2012, In: Breast Cancer Research (Online Edition). 14, 1, p. R33

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Breast Neoplasms 100%
  • Mutation 87%
  • Single Nucleotide Polymorphism 58%
  • Estrogen Receptors 32%
  • Alleles 25%
  65 Citations (Scopus)

• Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

  Couch, F. J., Gaudet, M. M., Antoniou, A. C., Ramus, S. J., Kuchenbaecker, K. B., Soucy, P., Beesley, J., Chen, X., Wang, X., Kirchhoff, T., McGuffog, L., Barrowdale, D., Lee, A. R., Healey, S., Sinilnikova, O. M., Andrulis, I. L., Ozcelik, H., Mulligan, A. M., Thomassen, M., Gerdes, A-M., & 31 othersJensen, U. B., Skytte, A-B., Kruse, T. A., Caligo, M. A., von Wachenfeldt, A., Barbany-Bustinza, G., Loman, N., Soller, M., Ehrencrona, H., Karlsson, P. W., Nathanson, K. L., Rebbeck, T. R., Domchek, S. M., Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Zlowocka, E., Huzarski, T., Byrski, T., Gronwald, J., Cybulski, C., Górski, B., Osorio, A., Durán, M., Tejada, M. I., Benitez, J., Hamann, U., Hogervorst, F. B. L., Nielsen, F. C. & OCGN, Apr 2012, In: Cancer Epidemiology, Biomarkers & Prevention. 21, 4, p. 645-57 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Estrogen Receptors 100%
  • Ovarian Neoplasms 97%
  • Breast Neoplasms 68%
  • Mutation 59%
  • Confidence Intervals 31%
  39 Citations (Scopus)

• Genetiske fund giver nye muligheder for udredning af arveligt malignt melanom

  Translated title of the contribution: The genes disposing to malignant melanoma--a systematic reviewWadt, K. A. W., Drzewiecki, K. T. & Gerdes, A-M. A., 2012, In: Ugeskrift for Laeger. 174, 8, p. 493-7 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Melanoma 100%
  • Systematic Reviews 88%
  • Genes 48%
  • Genetic Counseling 21%
  • Denmark 21%

• Is the SPINK1 variant p.N34S overrepresented in patients with acute pancreatitis?

  Jøergensen, M. T., Brusgaard, K., Novovic, S., Andersen, A. M., Hansen, M. B., Gerdes, A-M. & de Muckadell, O. B. S., Mar 2012, In: European Journal of Gastroenterology and Hepatology. 24, 3, p. 309-15 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Kazal Pancreatic Trypsin Inhibitor 100%
  • Pancreatitis 61%
  • Mutation 14%
  • Meta-Analysis 14%
  • Trypsinogen 9%
  5 Citations (Scopus)

• Klinisk genetik

  Skovby, F., Gerdes, A-M. A. & Hertz, J. M., 2012, Basisbog i diagnostiske fag. Thomsen, H. S. (ed.). 1 ed. København, p. 167-196

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

• Long-term effect of resistant starch on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial

  Mathers, J. C., Movahedi, M., Macrae, F., Mecklin, J-P., Moeslein, G., Olschwang, S., Eccles, D., Evans, G., Maher, E. R., Bertario, L., Bisgaard, S. M. L., Dunlop, M., Ho, J. W., Hodgson, S., Lindblom, A., Lubinski, J., Morrison, P. J., Murday, V., Ramesar, R., Side, L., & 14 othersScott, R. J., Thomas, H. J., Vasen, H., Gerdes, A-M., Barker, G., Crawford, G., Elliott, F., Pylvanainen, K., Wijnen, J., Fodde, R., Lynch, H., Bishop, D. T., Burn, J. & on behalf of the CAPP2 Investigators, Dec 2012, In: The Lancet Oncology. 13, 12, p. 1242-1249 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Starch 100%
  • Colorectal Neoplasms 70%
  • Randomized Controlled Trials 59%
  • Neoplasms 28%
  • Placebos 23%
  68 Citations (Scopus)

• Multiple self-healing squamous epithelioma er en arvelig tilstand med selvhelende hudkræft

  Translated title of the contribution: Multiple self-healing squamous epithelioma is an inherited self-healing skin cancer conditionBroesby-Olsen, S., Frandsen, S. K., Thomassen, M., Brandrup, F. & Gerdes, A-M., 23 Apr 2012, In: Ugeskrift for Laeger. 174, 17, p. 1149-51 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Keratoacanthoma familial 100%
  • Skin Neoplasms 49%
  • Transforming Growth Factor-beta Type I Receptor 22%
  • Genetic Background 16%
  • Neoplasms 15%

• Novel germline c-MET mutation in a family with hereditary papillary renal carcinoma

  Wadt, K., Gerdes, A-M., Hansen, T. V. O., Toft, B. G., Friis-Hansen, L. & Andersen, M. K., Sept 2012, In: Familial Cancer. 11, 3, p. 535-7 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Sporadic Papillary renal cell carcinoma 100%
  • Papillary Carcinoma 61%
  • Kidney Neoplasms 37%
  • Missense Mutation 34%
  • Renal Cell Carcinoma 32%
  10 Citations (Scopus)

• Ny genteknologisk diagnostik af familiær gastrointestinal stromal tumor

  Translated title of the contribution: A new genetic diagnosis of familiar gastrointestinal stromal tumourWadt, K., Andersen, M. K., Hansen, T. V. O. & Gerdes, A-M., 2012, In: Ugeskrift for Laeger. 174, 21, p. 1462-4 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Gastrointestinal Stromal Tumors 100%
  • Mutation 34%
  • Interstitial Cells of Cajal 29%
  • Germ-Line Mutation 23%
  • Hyperplasia 18%
  5 Citations (Scopus)

• Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers

  Ramus, S. J., Antoniou, A. C., Kuchenbaecker, K. B., Soucy, P., Beesley, J., Chen, X., McGuffog, L., Sinilnikova, O. M., Healey, S., Barrowdale, D., Lee, A. R., Thomassen, M., Gerdes, A-M., Kruse, T. A., Jensen, U. B., Skytte, A-B., Caligo, M. A., Liljegren, A., Lindblom, A., Olsson, H., & 31 othersKristoffersson, U., Stenmark-Askmalm, M., Melin, B., Domchek, S. M., Nathanson, K. L., Rebbeck, T. R., Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Złowocka, E., Gronwald, J., Huzarski, T., Byrski, T., Cybulski, C., Toloczko-Grabarek, A., Osorio, A., Benitez, J., Duran, M., Tejada, M-I., Hamann, U., Rookus, M., van Leeuwen, F. E., Aalfs, C. M., Meijers-Heijboer, H. E. J., van Asperen, C. J., van Roozendaal, K. E. P., Hoogerbrugge, N., Collée, J. M., Kriege, M. & SWE-BRCA, 1 Apr 2012, In: Human Mutation. 33, 4, p. 690-702 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ovarian Neoplasms 100%
  • Alleles 80%
  • Mutation 61%
  • Germ-Line Mutation 15%
  • Genome-Wide Association Study 14%
  28 Citations (Scopus)

• Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

  Mavaddat, N., Barrowdale, D., Andrulis, I. L., Domchek, S. M., Eccles, D., Nevanlinna, H., Ramus, S. J., Spurdle, A., Robson, M., Sherman, M., Mulligan, A. M., Couch, F. J., Engel, C., McGuffog, L., Healey, S., Sinilnikova, O. M., Southey, M. C., Terry, M. B., Goldgar, D., O'Malley, F., & 31 othersJohn, E. M., Janavicius, R., Tihomirova, L., Hansen, T. V. O., Nielsen, F. C., Osorio, A., Stavropoulou, A., Benítez, J., Manoukian, S., Peissel, B., Barile, M., Volorio, S., Pasini, B., Dolcetti, R., Putignano, A. L., Ottini, L., Radice, P., Hamann, U., Rashid, M. U., Hogervorst, F. B., Kriege, M., van der Luijt, R. B., Peock, S., Frost, D., Evans, D. G., Brewer, C., Walker, L., Rogers, M. T., Side, L. E., Gerdes, A-M. & for HEBON, Jan 2012, In: Cancer Epidemiology, Biomarkers & Prevention. 21, 1, p. 134-147 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Estrogen Receptors 100%
  • Ovarian Neoplasms 97%
  • Research Personnel 74%
  • Breast Neoplasms 68%
  • Pathology 67%
  338 Citations (Scopus)
• 2011

  A BRCA2 mutation incorrectly mapped in the original BRCA2 reference sequence, is a common West Danish founder mutation disrupting mRNA splicing

  Thomassen, M., Pedersen, I. S., Vogel, I., Hansen, T. V. O., Brasch-Andersen, C., Brasen, C. L., Crüger, D., Sunde, L. E. M., Nielsen, F. C., Jensen, U. B., Bisgaard, M. L., Borg, A., Gerdes, A-M. & Kruse, T. A., 1 Jul 2011, In: Breast Cancer Research and Treatment. 128, 1, p. 179-85 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Messenger RNA 100%
  • Mutation 98%
  • Denmark 46%
  • Ovarian Neoplasms 39%
  • Breast Neoplasms 27%
  4 Citations (Scopus)

• A putative Lynch syndrome family carrying MSH2 and MSH6 variants of uncertain significance-functional analysis reveals the pathogenic one

  Kantelinen, J., Hansen, T. V. O., Kansikas, M., Krogh, L. N., Korhonen, M. K., Ollila, S., Nyström, M., Gerdes, A-M. & Kariola, R., Sept 2011, In: Familial Cancer. 10, 3, p. 515-20 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Hereditary Nonpolyposis Colorectal Neoplasms 100%
  • DNA Mismatch Repair 72%
  • Mutation 25%
  • Colorectal Neoplasms 24%
  • Genes 18%
  2 Citations (Scopus)

• Arvelige cancersyndromer

  Translated title of the contribution: [Hereditary cancer syndromes]Gerdes, A-M. A., Aug 2011, In: Ugeskrift for Laeger. 173, 34, p. 2035-8 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Hereditary Neoplastic Syndromes 100%
  • Germ-Line Mutation 25%
  • Mutation 24%
  • High-Throughput Nucleotide Sequencing 21%
  • Genes 17%

• Biomedical informatics as support to individual healthcare in hereditary colon cancer: the Danish HNPCC system

  Bernstein, I. T., Lindorff-Larsen, K., Timshel, S., Brandt, C., Dinesen, B., Fenger, M., Gerdes, A-M. A., Iversen, L. H., Madsen, M. R., Okkels, H., Sunde, L. E. M., Rahr, H., Wikman, F. P. & Rossing, N. N., May 2011, In: Human Mutation. 32, 5, p. 551-6 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Informatics 100%
  • Colonic Neoplasms 71%
  • Delivery of Health Care 48%
  • Databases 47%
  • Communication 23%
  9 Citations (Scopus)

• Breast cancer after bilateral risk-reducing mastectomy

  Skytte, A-B., Crüger, D. G., Gerster, M., Laenkholm, A-V., Lang, C., Brøndum-Nielsen, K., Andersen, M. K., Sunde, L. E. M., Kølvraa, S. & Gerdes, A-M., May 2011, In: Clinical Genetics. 79, 5, p. 431-7 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Mastectomy 100%
  • Breast Neoplasms 57%
  • Salpingo-oophorectomy 29%
  • Mutation 25%
  • Genetic Counseling 24%
  37 Citations (Scopus)

• Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers

  Antoniou, A. C., Kartsonaki, C., Sinilnikova, O. M., Soucy, P., McGuffog, L., Healey, S., Lee, A. R., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Cattaneo, E., Barile, M., Pensotti, V., Pasini, B., Dolcetti, R., Giannini, G., Putignano, A. L., Varesco, L., Radice, P., & 31 othersMai, P. L., Greene, M. H., Andrulis, I. L., Glendon, G., Ozcelik, H., Thomassen, M., Gerdes, A-M., Kruse, T. A., Birk Jensen, U., Crüger, D. G., Caligo, M. A., Laitman, Y., Milgrom, R., Kaufman, B., Paluch-Shimon, S., Friedman, E., Loman, N., Harbst, K., Lindblom, A., Arver, B., Ehrencrona, H., Melin, B., Nathanson, K. L., Domchek, S. M., Rebbeck, T., Jakubowska, A., Lubinski, J., Gronwald, J., Huzarski, T., Byrski, T. & SWE-BRCA, 1 Aug 2011, In: Human Molecular Genetics. 20, 16, p. 3304-21 18 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Alleles 100%
  • Breast Neoplasms 87%
  • Single Nucleotide Polymorphism 80%
  • Mutation 76%
  • Confidence Intervals 40%
  56 Citations (Scopus)

• Common breast cancer susceptibility alleles are associated with tumor subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2

  Mulligan, A. M., Couch, F. J., Barrowdale, D., Domchek, S. M., Eccles, D., Nevanlinna, H., Ramus, S. J., Robson, M., Sherman, M., Spurdle, A. B., Wappenschmidt, B., Lee, A. R., McGuffog, L., Healey, S., Sinilnikova, O. M., Janavicius, R., Hansen, T. V. O., Nielsen, F. C., Ejlertsen, B., Osorio, A., & 169 othersMunoz-Repeto, I., Duran, M., Godino, J., Pertesi, M., Benitez, J., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Cattaneo, E., Bonanni, B., Viel, A., Pasini, B., Papi, L., Ottini, L., Savarese, A., Bernard, L., Radice, P., Hamann, U., Verheus, M., Meijers-Heijboer, H. E., Wijnen, J., Gomez Garcia, E. B., Nelen, M. R., Kets, C. M., Seynaeve, C., Tilanus-Linthorst, M. M., van der Luijt, R. B., van Os, T., Rookus, M., Frost, D., Jones, J. L., Evans, D. G., Lalloo, F., Eeles, R., Izatt, L., Adlard, J., Davidson, R., Cook, J., Donaldson, A., Dorkins, H., Gregory, H., Eason, J., Houghton, C., Barwell, J., Side, L. E., McCann, E., Murray, A., Peock, S., Godwin, A., Schmutzler, R. K., Rhiem, K., Engel, C., Meindl, A., Ruehl, I., Arnold, N., Niederacher, D., Sutter, C., Deissler, H., Gadzicki, D., Kast, K., Preisler-Adams, S., Varon-Mateeva, R., Schoenbuchner, I., Fiebig, B., Heinritz, W., Schafer, D., Gevensleben, H., Caux-Moncoutier, V., Fassy-Colcombet, M., Cornelis, F., Mazoyer, S., Leone, M., Boutry-Kryza, N., Hardouin, A., Berthet, P., Muller, D., Fricker, J-P., Mortemousque, I., Pujol, P., Coupier, I., Lebrun, M., Kientz, C., Longy, M., Sevenet, N., Stoppa-Lyonnet, D., Isaacs, C., Caldes, T., de Al Hoya, M., Heikkinen, T., Aittomaki, K., Blanco, I., Lazaro, C., Barkardottir, R. B., Soucy, P., Dumont, M., Simard, J., Montagna, M., Tognazzo, S., D'Andrea, E., Fox, S., Yan, M., Rebbeck, T. R., Olopade, O. I., Weitzel, J. N., Lynch, H. T., Ganz, P. A., Tomlinson, G. E., Wang, X., Fredericksen, Z., Pankratz, V. S., Lindor, N. M., Szabo, C., Offit, K., Sakr, R., Gaudet, M., Bhatia, J., Kauff, N., Singer, C. F., Tea, M-K., Gschwantler-Kaulich, D., Fink-Retter, A., Mai, P. L., Greene, M. H., Imyanitov, E., O'Malley, F. P., Ozcelik, H., Glendon, G., Toland, A. E., Gerdes, A-M., Thomassen, M., Kruse, T. A., Birk Jensen, U., Skytte, A-B., Caligo, M. A., Soller, M., Henriksson, K., von Wachenfeldt, A., Arver, B., Stenmark-Askmalm, M., Karlsson, P. W., Ding, Y. C., Neuhausen, S. L., Beattie, M., Pharoah, P. D., Moysich, K. B., Nathanson, K. L., Karlan, B. Y., Gross, J., John, E. M., Daly, M. B., Buys, S. M., Southey, M. C., Hopper, J. L., Terry, M. B., Chung, W., Miron, A. F., Goldgar, D., Chenevix-Trench, G., Easton, D. F., Andrulis, I. L., Antoniou, A. C., Family Registry, B. C., Embrace, Collaborators, G. S., Hebon, Network, O. C. G., Swe-Brca & Cimba, 2 Nov 2011, In: Breast Cancer Research (Online Edition). 13, 6, p. R110

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Estrogens 100%
  • Alleles 97%
  • Research Personnel 93%
  • Breast Neoplasms 85%
  • Mutation 74%
  53 Citations (Scopus)

• Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers

  Cox, D. G., Simard, J., Sinnett, D., Hamdi, Y., Soucy, P., Ouimet, M., Barjhoux, L., Verny-Pierre, C., McGuffog, L., Healey, S., Szabo, C., Greene, M. H., Mai, P. L., Andrulis, I. L., Thomassen, M., Gerdes, A-M., Caligo, M. A., Friedman, E., Laitman, Y., Kaufman, B., & 31 othersPaluch, S. S., Borg, Å., Karlsson, P. W., Askmalm, M. S., Bustinza, G. B., Nathanson, K. L., Domchek, S. M., Rebbeck, T. R., Benítez, J., Hamann, U., Rookus, M. A., van den Ouweland, A. M. W., Ausems, M. G. E. M., Aalfs, C. M., van Asperen, C. J., Devilee, P., Gille, H. J. J. P., Peock, S., Frost, D., Evans, D. G., Eeles, R., Izatt, L., Adlard, J., Paterson, J., Eason, J., Godwin, A. K., Remon, M-A., Moncoutier, V., Gauthier-Villars, M., Lasset, C. & Ontario Cancer Genetics Network, 1 Dec 2011, In: Human Molecular Genetics. 20, 23, p. 4732-47 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Alleles 100%
  • Breast Neoplasms 87%
  • Mutation 76%
  • BRCA1 Gene 74%
  • Haplotypes 51%
  21 Citations (Scopus)

• Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers

  Ramus, S. J., Kartsonaki, C., Gayther, S. A., Pharoah, P. D. P., Sinilnikova, O. M., Beesley, J., Chen, X., McGuffog, L., Healey, S., Couch, F. J., Wang, X., Fredericksen, Z., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Roversi, G., Barile, M., Viel, A., Allavena, A., & 31 othersOttini, L., Papi, L., Gismondi, V., Capra, F., Radice, P., Greene, M. H., Mai, P. L., Andrulis, I. L., Glendon, G., Ozcelik, H., Thomassen, M., Gerdes, A-M., Kruse, T. A., Cruger, D., Jensen, U. B., Caligo, M. A., Olsson, H., Kristoffersson, U., Lindblom, A., Arver, B., Karlsson, P. W., Stenmark Askmalm, M., Borg, A., Neuhausen, S. L., Ding, Y. C., Nathanson, K. L., Domchek, S. M., Hansen, T. V. O., Jønson, L., Ejlertsen, B. & OCGN, 19 Jan 2011, In: National Cancer Institute. Journal (Print). 103, 2, p. 105-16 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Genetic Variation 100%
  • Ovarian Neoplasms 94%
  • Mutation 57%
  • Single Nucleotide Polymorphism 34%
  • Alleles 30%
  34 Citations (Scopus)

• International distribution and age estimation of the Portuguese BRCA2 c.156_157insAlu founder mutation

  Peixoto, A., Santos, C., Pinheiro, M., Pinto, P., Soares, M. J., Rocha, P., Gusmão, L., Amorim, A., van der Hout, A., Gerdes, A-M., Thomassen, M., Kruse, T. A., Cruger, D., Sunde, L. E. M., Bignon, Y-J., Uhrhammer, N., Cornil, L., Rouleau, E., Lidereau, R., Yannoukakos, D., & 47 othersPertesi, M., Narod, S., Royer, R., Costa, M. M., Lazaro, C., Feliubadaló, L., Graña, B., Blanco, I., de la Hoya, M., Caldés, T., Maillet, P., Benais-Pont, G., Pardo, B., Laitman, Y., Friedman, E., Velasco, E. A., Durán, M., Miramar, M-D., Valle, A. R., Calvo, M-T., Vega, A., Blanco, A., Diez, O., Gutiérrez-Enríquez, S., Balmaña, J., ramon cajal, T., Alonso, C., Baiget, M., Foulkes, W., Tischkowitz, M., Kyle, R., Sabbaghian, N., Ashton-Prolla, P., Ewald, I. P., Rajkumar, T., Mota-Vieira, L., Giannini, G., Gulino, A., Achatz, M. I., Carraro, D. M., de Paillerets, B. B., Remenieras, A., Benson, C., Casadei, S., King, M-C., Teugels, E. & Teixeira, M. R., Jun 2011, In: Breast Cancer Research and Treatment. 127, 3, p. 671-9 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Age Distribution 100%
  • Mutation 50%
  • Ovarian Neoplasms 46%
  • Breast Neoplasms 41%
  • Portugal 31%
  21 Citations (Scopus)

• Intragenic duplication: a novel mutational mechanism in hereditary pancreatitis

  Joergensen, M. T., Geisz, A., Brusgaard, K., Schaffalitzky de Muckadell, O. B., Hegyi, P., Gerdes, A-M. A. & Sahin-Tóth, M., May 2011, In: Pancreas. 40, 4, p. 540-6 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Hereditary pancreatitis 100%
  • Trypsinogen 90%
  • Cathepsin B 22%
  • Trisomy Chromosome 9 15%
  • trypsinogen activation peptide 15%
  13 Citations (Scopus)

• Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial

  Burn, J., Gerdes, A-M., Macrae, F., Mecklin, J-P., Moeslein, G., Olschwang, S., Eccles, D., Evans, D. G., Maher, E. R., Bertario, L., Bisgaard, S. M. L., Dunlop, M. G., Ho, J. W. C., Hodgson, S. V., Lindblom, A., Lubinski, J., Morrison, P. J., Murday, V., Ramesar, R., Side, L., & 14 othersScott, R. J., Thomas, H. J. W., Vasen, H. F., Barker, G., Crawford, G., Elliott, F., Movahedi, M., Pylvanainen, K., Wijnen, J. T., Fodde, R., Lynch, H. T., Mathers, J. C., Bishop, D. T. & CAPP2 Investigators, 2011, In: Lancet. 378, 9809, p. 2081-7 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Aspirin 100%
  • Colorectal Neoplasms 86%
  • Randomized Controlled Trials 73%
  • Placebos 37%
  • Starch 35%
  665 Citations (Scopus)

• Multiple self-healing squamous epithelioma is caused by a disease-specific spectrum of mutations in TGFBR1

  Goudie, D. R., D'Alessandro, M., Merriman, B., Lee, H., Szeverényi, I., Avery, S., O'Connor, B. D., Nelson, S. F., Coats, S. E., Stewart, A., Christie, L., Pichert, G., Friedel, J., Hayes, I., Burrows, N., Whittaker, S., Gerdes, A-M. A., Broesby-Olsen, S., Ferguson-Smith, M. A., Verma, C., & 3 othersLunny, D. P., Reversade, B. & Lane, E. B., Feb 2011, In: Nature Genetics. 43, 4, p. 365-9 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Keratoacanthoma familial 100%
  • Transforming Growth Factor-beta Type I Receptor 66%
  • Mutation 26%
  • Chromosomes, Human, Pair 9 12%
  • Loss of Function Mutation 10%
  113 Citations (Scopus)

• Screening of 1331 Danish breast and/or ovarian cancer families identified 40 novel BRCA1 and BRCA2 mutations

  Hansen, T. V. O., Jønson, L., Steffensen, A. Y., Andersen, M. K., Kjaergaard, S., Gerdes, A-M., Ejlertsen, B. & Nielsen, F. C., Jun 2011, In: Familial Cancer. 10, 2, p. 207-12 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ovarian Neoplasms 100%
  • Missense Mutation 75%
  • Breast Neoplasms 70%
  • Mutation 61%
  • Computer Simulation 34%
  4 Citations (Scopus)
• 2010

  A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

  Antoniou, A. C., Wang, X., Fredericksen, Z. S., McGuffog, L., Tarrell, R., Sinilnikova, O. M., Healey, S., Morrison, J., Kartsonaki, C., Lesnick, T., Ghoussaini, M., Barrowdale, D., Peock, S., Cook, M., Oliver, C., Frost, D., Eccles, D., Evans, D. G., Eeles, R., Izatt, L., & 31 othersChu, C., Douglas, F., Paterson, J., Stoppa-Lyonnet, D., Houdayer, C., Mazoyer, S., Giraud, S., Lasset, C., Remenieras, A., Caron, O., Hardouin, A., Berthet, P., Hogervorst, F. B. L., Rookus, M. A., Jager, A., van den Ouweland, A., Hoogerbrugge, N., van der Luijt, R. B., Meijers-Heijboer, H., Gómez García, E. B., Devilee, P., Vreeswijk, M. P. G., Lubinski, J., Jakubowska, A., Gronwald, J., Huzarski, T., Byrski, T., Gerdes, A-M., Hansen, T. V. O., Nielsen, F. C. & EMBRACE, 1 Oct 2010, In: Nature Genetics. 42, 10, p. 885-92 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Hormones 100%
  • Breast Neoplasms 90%
  • Mutation 79%
  • Single Nucleotide Polymorphism 79%
  • Population 55%
  253 Citations (Scopus)

• Identification of a Danish breast/ovarian cancer family double heterozygote for BRCA1 and BRCA2 mutations

  Steffensen, A. Y., Jønson, L., Ejlertsen, B., Gerdes, A-M., Nielsen, F. C. & Hansen, T. V. O., 1 Sept 2010, In: Familial Cancer. 9, 3, p. 283-7 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Heterozygote 100%
  • Ovarian Neoplasms 85%
  • Breast Neoplasms 59%
  • Mutation 52%
  • Exons 17%
  13 Citations (Scopus)

• Medullary thyroid cancer: RET testing of an archival material

  Godballe, C., Jørgensen, G., Gerdes, A-M. A., Krogdahl, A. S., Tybjaerg-Hansen, A. & Nielsen, F. C., 1 Apr 2010, In: European Archives of Oto-Rhino-Laryngology. 267, 4, p. 613-7 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Materials Testing 100%
  • Medullary Thyroid cancer 92%
  • Mutation 17%
  • Proto-Oncogenes 12%
  • DNA 11%
  7 Citations (Scopus)

• Risk-reducing mastectomy and salpingo-oophorectomy in unaffected BRCA mutation carriers: uptake and timing

  Skytte, A-B., Gerdes, A-M. A., Andersen, M. K., Sunde, L., Brøndum-Nielsen, K., Waldstrøm, M., Kølvraa, S., Crüger, D., Skytte, A-B., Gerdes, A-M., Andersen, M. K., Sunde, L., Brøndum-Nielsen, K., Waldstrøm, M., Kølvraa, S. & Crüger, D., 1 Apr 2010, In: Clinical Genetics. 77, 4, p. 342-9 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Salpingo-oophorectomy 100%
  • Mastectomy 85%
  • Mutation 43%
  • Prophylactic Mastectomy 29%
  • Risk Management 21%
  75 Citations (Scopus)
• 2009

  Functional characterization of rare missense mutations in MLH1 and MSH2 identified in Danish colorectal cancer patients

  Christensen, L. L., Kariola, R., Korhonen, M. K., Wikman, F. P., Sunde, L., Gerdes, A-M., Okkels, H., Brandt, C. A., Bernstein, I., Hansen, T. V. O., Hagemann-Madsen, R., Andersen, C. L., Nyström, M., Ørntoft, T. F., Christensen, L., Kariola, R., Korhonen, M., Wikman, F., Sunde, L., Gerdes, A-M., & 8 othersOkkels, H., Brandt, C., Bernstein, I., Hansen, T., Hagemann-Madsen, R., Andersen, C., Nyström, M. & Orntoft, T., 2009, In: Familial Cancer. 8, 4, p. 489-500 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Missense Mutation 100%
  • Colorectal Neoplasms 76%
  • Proteins 31%
  • Mutation 24%
  • Virulence 18%
  8 Citations (Scopus)
• 2000

  Frequent disruption of the RB1 pathway in diffuse large B cell lymphoma: prognostic significance of E2F-1 and p16INK4A

  Møller, M. B., Kania, P. W., Ino, Y., Gerdes, A. M., Nielsen, O., Louis, D. N., Skjødt, K. & Pedersen, N. T., May 2000, In: Leukemia. 14, 5, p. 898-904 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cyclin D3 100%
  • Lymphoma, Large B-Cell, Diffuse 75%
  • Lymphoma 44%
  • Cyclin D1 14%
  • Tumor Suppressor Genes 13%
  57 Citations (Scopus)