TY - JOUR
T1 - Viruses.STRING
T2 - A Virus-Host Protein-Protein Interaction Database
AU - Cook, Helen Victoria
AU - Doncheva, Nadezhda Tsankova
AU - Szklarczyk, Damian
AU - von Mering, Christian
AU - Jensen, Lars Juhl
PY - 2018
Y1 - 2018
N2 - As viruses continue to pose risks to global health, having a better understanding of virus⁻host protein⁻protein interactions aids in the development of treatments and vaccines. Here, we introduce Viruses.STRING, a protein⁻protein interaction database specifically catering to virus⁻virus and virus⁻host interactions. This database combines evidence from experimental and text-mining channels to provide combined probabilities for interactions between viral and host proteins. The database contains 177,425 interactions between 239 viruses and 319 hosts. The database is publicly available at viruses.string-db.org, and the interaction data can also be accessed through the latest version of the Cytoscape STRING app.
AB - As viruses continue to pose risks to global health, having a better understanding of virus⁻host protein⁻protein interactions aids in the development of treatments and vaccines. Here, we introduce Viruses.STRING, a protein⁻protein interaction database specifically catering to virus⁻virus and virus⁻host interactions. This database combines evidence from experimental and text-mining channels to provide combined probabilities for interactions between viral and host proteins. The database contains 177,425 interactions between 239 viruses and 319 hosts. The database is publicly available at viruses.string-db.org, and the interaction data can also be accessed through the latest version of the Cytoscape STRING app.
KW - PPI database
KW - Protein
KW - Protein interactions
KW - Virus bioinformatics
KW - Virus-host interactions
KW - virus bioinformatics
KW - virus-host interactions
KW - protein-protein interactions
U2 - 10.3390/v10100519
DO - 10.3390/v10100519
M3 - Journal article
C2 - 30249048
SN - 1999-4915
VL - 10
SP - 1
EP - 11
JO - Viruses
JF - Viruses
IS - 10
M1 - 519
ER -