U-turns and regulatory RNAs

T Franch; K Gerdes

doi:10.1016/S1369-5274(00)00069-2

U-turns and regulatory RNAs

54 Citationer (Scopus)

Abstract

Conventional antisense RNAs, such as those controlling plasmid replication and maintenance, inhibit the function of their target RNAs rapidly and efficiently Novel findings show that a common Ii-turn loop structure mediates fast RNA pairing in the majority of these RNA controlled systems. Usually, an antisense RNA regulates a single, cognate target RNA only. Recent reports, however, show that antisense RNAs can act as promiscuous regulators that control multiple genes in concert to integrate complex physiological responses in Escherichia coli.

Originalsprog	Engelsk
Tidsskrift	Current Opinion in Microbiology
Vol/bind	3
Udgave nummer	2
Sider (fra-til)	159-164
Antal sider	6
ISSN	1369-5274
DOI	https://doi.org/10.1016/S1369-5274(00)00069-2
Status	Udgivet - 2000
Udgivet eksternt	Ja

Adgang til dokumentet

10.1016/S1369-5274(00)00069-2

Citationsformater

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AB - Conventional antisense RNAs, such as those controlling plasmid replication and maintenance, inhibit the function of their target RNAs rapidly and efficiently Novel findings show that a common Ii-turn loop structure mediates fast RNA pairing in the majority of these RNA controlled systems. Usually, an antisense RNA regulates a single, cognate target RNA only. Recent reports, however, show that antisense RNAs can act as promiscuous regulators that control multiple genes in concert to integrate complex physiological responses in Escherichia coli.

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